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Protein
Submitted name:

SUCcinyl-CoA Ligase, alpha subunit

Gene

sucl-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei278 – 2781Tele-phosphohistidine intermediateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-CEL-71403. Citric acid cycle (TCA cycle).

Names & Taxonomyi

Protein namesi
Submitted name:
SUCcinyl-CoA Ligase, alpha subunitImported
Gene namesi
Name:sucl-2Imported
ORF Names:CELE_F23H11.3Imported, F23H11.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF23H11.3; CE09611; WBGene00017759; sucl-2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO02642.
PaxDbiO02642.

Interactioni

Protein-protein interaction databases

DIPiDIP-25090N.
MINTiMINT-1087292.
STRINGi6239.F23H11.3.1.

Structurei

3D structure databases

ProteinModelPortaliO02642.
SMRiO02642. Positions 22-317.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 12697CoA_bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the succinate/malate CoA ligase alpha subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1255. Eukaryota.
COG0074. LUCA.
GeneTreeiENSGT00530000063275.
HOGENOMiHOG000239685.
InParanoidiO02642.
KOiK01899.
OMAiGDCKIGI.
OrthoDBiEOG74BJSG.
PhylomeDBiO02642.

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O02642-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTLASAAR AATRAAVTRS VYNDTRNNLM INKSTKVIVQ GFTGRQGTFH
60 70 80 90 100
SKQMLEYNTN LVGGVSPNKA GQTHLGLPVF GSVAEAKDRT GADATVIYVP
110 120 130 140 150
AAGAARAIHE AMDAEIGLIV AITEGIPQQD MVRVKNRLLK QNKSRLLGPN
160 170 180 190 200
CPGIIASGDC KIGIMPGHIH KKGCIGIVSR SGTLTYEAVH QTTTVGLGQT
210 220 230 240 250
RCIGIGGDPF NGTNFIDCLE VFLEDEQTKG IILIGEIGGQ AEEQAAEFLK
260 270 280 290 300
SRNSGSNAKP VVSFIAGVTA PPGRRMGHAG AIIAGGKGTA GDKIEALRNA
310 320
NVVVTDSPAK LGVAMQKALL G
Length:321
Mass (Da):33,366
Last modified:July 1, 1997 - v1
Checksum:iFBE0AEEA412EF4F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD69944.1.
PIRiT34065.
RefSeqiNP_497288.1. NM_064887.5.
UniGeneiCel.37553.

Genome annotation databases

EnsemblMetazoaiF23H11.3.1; F23H11.3.1; WBGene00017759.
F23H11.3.2; F23H11.3.2; WBGene00017759.
GeneIDi175252.
KEGGicel:CELE_F23H11.3.
UCSCiF23H11.3.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD69944.1.
PIRiT34065.
RefSeqiNP_497288.1. NM_064887.5.
UniGeneiCel.37553.

3D structure databases

ProteinModelPortaliO02642.
SMRiO02642. Positions 22-317.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-25090N.
MINTiMINT-1087292.
STRINGi6239.F23H11.3.1.

Proteomic databases

EPDiO02642.
PaxDbiO02642.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF23H11.3.1; F23H11.3.1; WBGene00017759.
F23H11.3.2; F23H11.3.2; WBGene00017759.
GeneIDi175252.
KEGGicel:CELE_F23H11.3.
UCSCiF23H11.3.1. c. elegans.

Organism-specific databases

CTDi175252.
WormBaseiF23H11.3; CE09611; WBGene00017759; sucl-2.

Phylogenomic databases

eggNOGiKOG1255. Eukaryota.
COG0074. LUCA.
GeneTreeiENSGT00530000063275.
HOGENOMiHOG000239685.
InParanoidiO02642.
KOiK01899.
OMAiGDCKIGI.
OrthoDBiEOG74BJSG.
PhylomeDBiO02642.

Enzyme and pathway databases

ReactomeiR-CEL-71403. Citric acid cycle (TCA cycle).

Family and domain databases

Gene3Di3.40.50.261. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 1 hit.
[Graphical view]
PIRSFiPIRSF001553. SucCS_alpha. 1 hit.
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF52210. SSF52210. 1 hit.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS01216. SUCCINYL_COA_LIG_1. 1 hit.
PS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO02642_CAEEL
AccessioniPrimary (citable) accession number: O02642
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: July 6, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.