Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O02609 (PGK_OXYNO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK
OrganismOxytricha nova
Taxonomic identifier200597 [NCBI]
Taxonomic lineageEukaryotaAlveolataCiliophoraIntramacronucleataSpirotricheaStichotrichiaSporadotrichidaOxytrichidaeStylonychinaeSterkiella

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 419419Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145857

Regions

Nucleotide binding373 – 3764ATP By similarity
Region25 – 273Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1231Substrate By similarity
Binding site1701Substrate By similarity
Binding site2191ATP By similarity
Binding site3131ATP; via carbonyl oxygen By similarity
Binding site3441ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
O02609 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 83B999ECD3B99C7C

FASTA41945,166
        10         20         30         40         50         60 
MLSKKLAIDH IPHLIKGKRV LMRVDFNVPI KEGKIKDLTR IQGALPSINY CLENGAESVV 

        70         80         90        100        110        120 
LMSHLGRPDG QRVEKHSLKP VLPAIEDLLK KKVQFLDDCV GSEVERECKS ASKGKVILLE 

       130        140        150        160        170        180 
NLRFHLAEEG KGVINGEKVK ATKEDIAAFR KSLTSLGELY VNDGFGTAHR AHSSMVGVNV 

       190        200        210        220        230        240 
DTRAAGFLLK KELQYFSKIL ETPERPLTVV MGGAKVADKI QLIMKLLELA DELIIGGGMA 

       250        260        270        280        290        300 
FTFNKVLDGS NIGKSLFDQE GAKIVPDIIK KAKERGVKIH LPVDAVAADK FEESAATQLV 

       310        320        330        340        350        360 
DLKTGAIPDG WMGLDIGPKT IEQNSRVILR AKTVFWNGPQ GVFEMAPFSK GSLSMLDDII 

       370        380        390        400        410 
KATQTGATSV AGGGDTVSLL GKVKGTTDKF SHVSTGGGAS LELLQGKQLP GVVALSDRQ 

« Hide

References

[1]Pearlman R.E.
Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF001848 Genomic DNA. Translation: AAB58240.1.

3D structure databases

ProteinModelPortalO02609.
SMRO02609. Positions 2-417.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO02609.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_OXYNO
AccessionPrimary (citable) accession number: O02609
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways