Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cysteine proteinase

Gene
N/A
Organism
Spirometra erinaceieuropaei (Tapeworm) (Spirometra erinacei)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiI29.003.

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine proteinaseImported
OrganismiSpirometra erinaceieuropaei (Tapeworm) (Spirometra erinacei)Imported
Taxonomic identifieri99802 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesCestodaEucestodaDiphyllobothriideaDiphyllobothriidaeSpirometra

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919UniRule annotationAdd
BLAST
Chaini20 – 336317UniRule annotationPRO_5005735284Add
BLAST

Structurei

3D structure databases

SMRiO02586. Positions 121-336.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 9261Inhibitor_I29InterPro annotationAdd
BLAST
Domaini121 – 335215Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O02586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFVIYVAFL FLLLTVCRGS TESETYVRRE LWKAWKLAFK KEYFSSEEEL
60 70 80 90 100
HRKRAFFNNL DFIIRHNQRY YQQLESYAVR LNDFSDLTPG EFAERYLCLR
110 120 130 140 150
GIVLTKLRRK EAVSVPLKEN LPDSVNWRER GAVTSVKNQG QCGSCWSFSA
160 170 180 190 200
NGAIEGAIQI KTGALRSLSE QQLMDCSWDY GNQGCNGGLM PQAFQYAQRY
210 220 230 240 250
GVEAEVDYRY TERDGVCRYR QDLVVANVTG YAELPEGDEG GLQRAVATIG
260 270 280 290 300
PISVGIDAAD PGFMSYSHGV FVSKTCSPYA IDHGVLVVGY GAENGDAYWL
310 320 330
VKNSWGSSWG EDGYLKMARN RNNMCGIASM ASYPTV
Length:336
Mass (Da):37,872
Last modified:July 1, 1997 - v1
Checksum:i7072283F52C0FFDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63670 mRNA. Translation: BAA09820.1.
D63671 Genomic DNA. Translation: BAA09821.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D63670 mRNA. Translation: BAA09820.1.
D63671 Genomic DNA. Translation: BAA09821.1.

3D structure databases

SMRiO02586. Positions 121-336.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI29.003.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiPF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
[Graphical view]
PROSITEiPS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning and expression of the gene encoding a cysteine proteinase of spirometra erinacei."
    Liu D., Kato H., Nakamura T., Sugane K.
    Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Molecular cloning and expression of the gene encoding a cysteine proteinase of Spirometra erinacei."
    Liu D.W., Kato H., Nakamura T., Sugane K.
    Mol. Biochem. Parasitol. 76:11-21(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO02586_SPIER
AccessioniPrimary (citable) accession number: O02586
Secondary accession number(s): O02585
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.