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O02389 (TPM_CHLNI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 24, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Subunit structure

Homodimer By similarity.

Domain

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similarities

Belongs to the tropomyosin family.

Ontologies

Keywords
   DomainCoiled coil
Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Tropomyosin
PRO_0000205664

Regions

Coiled coil1 – 284284 By similarity

Sequences

Sequence LengthMass (Da)Tools
O02389 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 4E5C2EC80517791E

FASTA28432,542
        10         20         30         40         50         60 
MDAIKKKMQA MKVDRENAQD LAEQMEQKLK DTETAKAKLE EDFNDLQKKL TTTENNFDVA 

        70         80         90        100        110        120 
NEQLQEANTK LENSDKQITQ LESDVGALQR RLQLLEEDFE RSEEKLATTT EKLEEASKAA 

       130        140        150        160        170        180 
DESERNRKVL EGRSNTAEER IDVLEKQLET AKNVATDADQ KFDEAARKLA ITEVDLERAE 

       190        200        210        220        230        240 
TRLEAADAKV HELEEELTVV GANIKTLQVQ NDQASQREDS YEETIRDLSK NLKDAETRAT 

       250        260        270        280 
EAERQLTKLQ KEVDRLEDEL LAEKERYKAI SDELDQTFAE IAGY 

« Hide

References

[1]"Chlamys nipponensis mRNA for tropomyosin, complete cds."
Nishita K., Inoue A., Ojima T.
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB021681 mRNA. Translation: BAA36219.1.

3D structure databases

ProteinModelPortalO02389.
SMRO02389. Positions 1-282.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO02389.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR000533. Tropomyosin.
[Graphical view]
PfamPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSPR00194. TROPOMYOSIN.
PROSITEPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPM_CHLNI
AccessionPrimary (citable) accession number: O02389
Entry history
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: July 1, 1997
Last modified: July 24, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families