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Protein

Tropomyosin

Gene
N/A
Organism
Chlamys nipponensis akazara (Akazara scallop) (Japanese scallop)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Names & Taxonomyi

Protein namesi
Recommended name:
Tropomyosin
OrganismiChlamys nipponensis akazara (Akazara scallop) (Japanese scallop)
Taxonomic identifieri6571 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaPectinoidaPectinoideaPectinidaeChlamys

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284TropomyosinPRO_0000205664Add
BLAST

Proteomic databases

PRIDEiO02389.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO02389.
SMRiO02389. Positions 1-282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili1 – 284284By similarityAdd
BLAST

Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similaritiesi

Belongs to the tropomyosin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O02389-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMQA MKVDRENAQD LAEQMEQKLK DTETAKAKLE EDFNDLQKKL
60 70 80 90 100
TTTENNFDVA NEQLQEANTK LENSDKQITQ LESDVGALQR RLQLLEEDFE
110 120 130 140 150
RSEEKLATTT EKLEEASKAA DESERNRKVL EGRSNTAEER IDVLEKQLET
160 170 180 190 200
AKNVATDADQ KFDEAARKLA ITEVDLERAE TRLEAADAKV HELEEELTVV
210 220 230 240 250
GANIKTLQVQ NDQASQREDS YEETIRDLSK NLKDAETRAT EAERQLTKLQ
260 270 280
KEVDRLEDEL LAEKERYKAI SDELDQTFAE IAGY
Length:284
Mass (Da):32,542
Last modified:July 1, 1997 - v1
Checksum:i4E5C2EC80517791E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB021681 mRNA. Translation: BAA36219.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB021681 mRNA. Translation: BAA36219.1.

3D structure databases

ProteinModelPortaliO02389.
SMRiO02389. Positions 1-282.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO02389.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Chlamys nipponensis mRNA for tropomyosin, complete cds."
    Nishita K., Inoue A., Ojima T.
    Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiTPM_CHLNI
AccessioniPrimary (citable) accession number: O02389
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: July 1, 1997
Last modified: October 1, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.