O02389 (TPM_CHLNI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Tropomyosin
Organism	Chlamys nipponensis akazara (Akazara scallop) (Japanese scallop)
Taxonomic identifier	6571 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Bivalvia › Pteriomorphia › Pectinoida › Pectinoidea › Pectinidae › Chlamys › Chlamys nipponensis

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
Subunit structure	Homodimer By similarity.
Domain	The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
Sequence similarities	Belongs to the tropomyosin family.

Ontologies

Keywords
Domain	Coiled coil Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	Tropomyosin		PRO_0000205664
Regions
	Coiled coil	1 – 284	284	By similarity

Sequences

	Sequence		Length	Mass (Da)
	O02389 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: 4E5C2EC80517791E	FASTA	284	32,542
	10 20 30 40 50 60 MDAIKKKMQA MKVDRENAQD LAEQMEQKLK DTETAKAKLE EDFNDLQKKL TTTENNFDVA 70 80 90 100 110 120 NEQLQEANTK LENSDKQITQ LESDVGALQR RLQLLEEDFE RSEEKLATTT EKLEEASKAA 130 140 150 160 170 180 DESERNRKVL EGRSNTAEER IDVLEKQLET AKNVATDADQ KFDEAARKLA ITEVDLERAE 190 200 210 220 230 240 TRLEAADAKV HELEEELTVV GANIKTLQVQ NDQASQREDS YEETIRDLSK NLKDAETRAT 250 260 270 280 EAERQLTKLQ KEVDRLEDEL LAEKERYKAI SDELDQTFAE IAGY

References

[1]	"Chlamys nipponensis mRNA for tropomyosin, complete cds." Nishita K., Inoue A., Ojima T. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB021681 mRNA. Translation: BAA36219.1.
3D structure databases
ProteinModelPortal	O02389.
SMR	O02389. Positions 1-282.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR000533. Tropomyosin. [Graphical view]
Pfam	PF00261. Tropomyosin. 1 hit. [Graphical view]
PRINTS	PR00194. TROPOMYOSIN.
PROSITE	PS00326. TROPOMYOSIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TPM_CHLNI

Accession

Primary (citable) accession number: O02389

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 16, 2004
Last sequence update:	July 1, 1997
Last modified:	October 3, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)