Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mite group 2 allergen Tyr p 2

Gene
N/A
Organism
Tyrophagus putrescentiae (Mold mite) (Acarus putrescentiae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite group 2 allergen Tyr p 2
Alternative name(s):
Allergen: Typ p 2
OrganismiTyrophagus putrescentiae (Mold mite) (Acarus putrescentiae)
Taxonomic identifieri59818 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataAcaroideaAcaridaeTyrophaginaeTyrophagus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3511. Tyr p 2.0101.
657. Tyr p 2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 151 PublicationAdd BLAST15
ChainiPRO_000001986516 – 141Mite group 2 allergen Tyr p 2Add BLAST126

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi23 ↔ 132By similarity
Disulfide bondi36 ↔ 41By similarity
Disulfide bondi87 ↔ 92By similarity
Glycosylationi103N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliO02380.
SMRiO02380.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NPC2 family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR014756. Ig_E-set.
IPR003172. ML_dom.
PfamiView protein in Pfam
PF02221. E1_DerP2_DerF2. 1 hit.
SMARTiView protein in SMART
SM00737. ML. 1 hit.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O02380-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFLILFALV AVAAAGQVKF TDCGKKEIAS VAVDGCEGDL CVIHKSKPVH
60 70 80 90 100
VIAEFTANQD TCKIEVKVTG QLNGLEVPIP GIETDGCKVL KCPLKKGTKY
110 120 130 140
TMNYSVNVPS VVPNIKTVVK LLATGEHGVL ACGAVNTDVK P
Length:141
Mass (Da):14,852
Last modified:July 1, 1997 - v1
Checksum:i38EF9520010A04C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12690 mRNA. Translation: CAA73221.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiALL2_TYRPU
AccessioniPrimary (citable) accession number: O02380
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: May 10, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families