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Protein
Submitted name:

CaLPain family

Gene

clp-8

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei130PROSITE-ProRule annotation1
Active sitei278PROSITE-ProRule annotation1
Active sitei298PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteasePROSITE-ProRule annotation

Protein family/group databases

MEROPSiC02.A08

Names & Taxonomyi

Protein namesi
Submitted name:
CaLPain familyImported
Gene namesi
Name:clp-8Imported
ORF Names:CELE_F44F1.3Imported, F44F1.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF44F1.3 ; CE36160 ; WBGene00009695 ; clp-8

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiO02260

Expressioni

Gene expression databases

BgeeiWBGene00009695

Interactioni

Protein-protein interaction databases

STRINGi6239.F44F1.3

Structurei

3D structure databases

ProteinModelPortaliO02260
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 352Calpain catalyticInterPro annotationAdd BLAST296

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0045 Eukaryota
ENOG410XP0B LUCA
GeneTreeiENSGT00750000117668
InParanoidiO02260
OMAiHENEKEA
OrthoDBiEOG091G02OL
PhylomeDBiO02260

Family and domain databases

CDDicd00044 CysPc, 1 hit
InterProiView protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR038765 Papain_like_cys_pep_sf
IPR001300 Peptidase_C2_calpain_cat
PfamiView protein in Pfam
PF00648 Peptidase_C2, 1 hit
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00230 CysPc, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit

Sequencei

Sequence statusi: Complete.

O02260-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSPQEEELL ELIEKYNEDK YCTNMNWTIF LGDHENEKEA NEKFKSILED
60 70 80 90 100
CQRSKSAFID KEFPHEPKSY MTFDEQSKVY GKYESWKTWL FPKIWRRITP
110 120 130 140 150
PSTDVSSSLS VYNPLTFTAY EVFQRKVGDC GLVAALSAIS TKPEVIMNIF
160 170 180 190 200
DSLQLSKYGV YKVKLFVDGQ WKTIIIDDYF PYTTDGIRIG ATSGYQIWAA
210 220 230 240 250
LIEKALVKEC GNYKGIHGFQ SLSAFSALTG SPVLLIPVAK MFNNLRKYWK
260 270 280 290 300
TLMEFRNNQY PMACGTLNRE VNGILPQHAY TIMDIVERDG HKLLLLRNPS
310 320 330 340 350
GGSVWTRNWS KEWEWWPENM KDLLEGMIRG SFWISWDDFL NVFCSIYVCR
360 370 380 390 400
HRSNWFAYYA KLVLKYPEDD AFPAIDIKVT EKCMVCISAV DDWISREVLL
410 420 430 440 450
KTVEFQMPKY VQRYSWIAVH KINGIFSDNK KVVACEIIND STQDIDLEPG
460 470 480 490 500
IYTITVIYLN DWSLDKRDIS IHSSRPISVN EGFSRTRKDS VHIKYIVDKF
510 520 530 540 550
GQEIVKEQKD KMSIKKYTDN NFTFIAVVAW NFTYDQFLHA HLRYSITDEQ
560 570 580 590 600
FVSRSLEDKQ TVDVIPPRRH QVLVVINLEA MPEIVDFPID IDYKLSKDVD
610 620 630 640
ATINGIKRGC HLPEISSSRF LEYVHREEII SLDDFIPEIE VLSKLN
Length:646
Mass (Da):75,294
Last modified:July 5, 2004 - v3
Checksum:iBAC35540A68F78CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB03101.3
PIRiT22177
RefSeqiNP_493327.2, NM_060926.2
UniGeneiCel.18718

Genome annotation databases

EnsemblMetazoaiF44F1.3; F44F1.3; WBGene00009695
GeneIDi185746
KEGGicel:CELE_F44F1.3
UCSCiF44F1.3 c. elegans

Entry informationi

Entry nameiO02260_CAEEL
AccessioniPrimary (citable) accession number: O02260
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 122 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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