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Protein

Nuclear hormone receptor family member nhr-136

Gene

nhr-136

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi50 – 129Nuclear receptorPROSITE-ProRule annotationAdd BLAST80
Zinc fingeri53 – 73NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri89 – 112NR C4-typePROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-136
Gene namesi
Name:nhr-136
ORF Names:C13C4.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC13C4.3; CE39470; WBGene00003726; nhr-136.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000538041 – 435Nuclear hormone receptor family member nhr-136Add BLAST435

Proteomic databases

PaxDbiO01930.

Expressioni

Gene expression databases

BgeeiWBGene00003726.

Structurei

3D structure databases

ProteinModelPortaliO01930.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri53 – 73NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri89 – 112NR C4-typePROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410K8AN. Eukaryota.
ENOG4110KJ3. LUCA.
GeneTreeiENSGT00530000064480.
HOGENOMiHOG000280716.
InParanoidiO01930.
OMAiCLLNYGS.
OrthoDBiEOG091G08CY.
PhylomeDBiO01930.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O01930-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPDFITVPS TSEKCLSPEL LLPNMDENLE DSKPSSLKYQ KAMMSRGTCP
60 70 80 90 100
SNCKVCRHSA TGYHYDVPSC NGCKTFFRRS ILDGRKYTCL KMRKCLSGTE
110 120 130 140 150
PVDLSRRMCR ACRFEKCVEA GMNPSAIQAD MKTTDGELLR KEIMIKQKTA
160 170 180 190 200
VDFLNTPQVI MSFEDKVQGI IGKLTVMELK IEPLYTGGLP PGNRDIRKLD
210 220 230 240 250
ELIDAPLILS YDEIPNLKYC PSVDELTGEI KPSGACYIHC GYLASIEYSK
260 270 280 290 300
MFDFAHKIDV ASKATLIKHA TIMCADIMTA FFSYYQRKSD RLIHPNGMFA
310 320 330 340 350
GPPKYRYGEA GTKYQASMQR TLATVLRHEL NRIEYMLLKA IVLCNPAVSS
360 370 380 390 400
LSISVQQIIG KEREEYVRTL LTYCLLNYGS VHGPSRFSAL LAIMSVLESQ
410 420 430
QKNAKDFHLL AKATILKDAV RYTRISNLYE QIMES
Length:435
Mass (Da):49,080
Last modified:May 30, 2006 - v2
Checksum:iD63CB2980EA33A60
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z92825 Genomic DNA. Translation: CAB07314.2.
PIRiT19235.
RefSeqiNP_506039.2. NM_073638.3.
UniGeneiCel.24860.

Genome annotation databases

EnsemblMetazoaiC13C4.3; C13C4.3; WBGene00003726.
GeneIDi182566.
KEGGicel:CELE_C13C4.3.
UCSCiC13C4.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z92825 Genomic DNA. Translation: CAB07314.2.
PIRiT19235.
RefSeqiNP_506039.2. NM_073638.3.
UniGeneiCel.24860.

3D structure databases

ProteinModelPortaliO01930.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiO01930.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC13C4.3; C13C4.3; WBGene00003726.
GeneIDi182566.
KEGGicel:CELE_C13C4.3.
UCSCiC13C4.3. c. elegans.

Organism-specific databases

CTDi182566.
WormBaseiC13C4.3; CE39470; WBGene00003726; nhr-136.

Phylogenomic databases

eggNOGiENOG410K8AN. Eukaryota.
ENOG4110KJ3. LUCA.
GeneTreeiENSGT00530000064480.
HOGENOMiHOG000280716.
InParanoidiO01930.
OMAiCLLNYGS.
OrthoDBiEOG091G08CY.
PhylomeDBiO01930.

Miscellaneous databases

PROiO01930.

Gene expression databases

BgeeiWBGene00003726.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNH136_CAEEL
AccessioniPrimary (citable) accession number: O01930
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: May 30, 2006
Last modified: November 2, 2016
This is version 116 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.