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Protein

Fatty acid-binding protein homolog 6

Gene

lbp-6

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei110 – 1101Fatty acidBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

Lipid-binding

Enzyme and pathway databases

ReactomeiR-CEL-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.
R-CEL-2453902. The canonical retinoid cycle in rods (twilight vision).
R-CEL-5362517. Signaling by Retinoic Acid.
R-CEL-5365859. RA biosynthesis pathway.
R-CEL-975634. Retinoid metabolism and transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein homolog 6
Gene namesi
Name:lbp-6
ORF Names:W02D3.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiW02D3.5; CE14426; WBGene00002258; lbp-6.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 135135Fatty acid-binding protein homolog 6PRO_0000067424Add
BLAST

Proteomic databases

EPDiO01812.
PaxDbiO01812.

2D gel databases

World-2DPAGE0020:O01812.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
lap-1P346292EBI-327961,EBI-332157

Protein-protein interaction databases

BioGridi37838. 3 interactions.
DIPiDIP-27012N.
IntActiO01812. 2 interactions.
MINTiMINT-1053545.
STRINGi6239.W02D3.5.2.

Structurei

3D structure databases

ProteinModelPortaliO01812.
SMRiO01812. Positions 5-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1323Fatty acid bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
InParanoidiO01812.
OMAiPDDRHVK.
PhylomeDBiO01812.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O01812-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEFVGRWK LIHSENFEEY MKEVGVGLIT RKAAANLKPT LEIKVEGDLW
60 70 80 90 100
YSNQYSTFKN TTLSFKLGQE FDETTPDGRT VKSVVNFENG KFIHIQKKIK
110 120 130
DSDKESIITR WLEGDKLITT LESGSVVSRR EYVRE
Length:135
Mass (Da):15,641
Last modified:July 1, 1997 - v1
Checksum:iD84E71652EBE83C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081084 Genomic DNA. Translation: CCD68988.1.
PIRiT15205.
RefSeqiNP_491926.1. NM_059525.4.
UniGeneiCel.30369.

Genome annotation databases

EnsemblMetazoaiW02D3.5; W02D3.5; WBGene00002258.
GeneIDi172390.
KEGGicel:CELE_W02D3.5.
UCSCiW02D3.5.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081084 Genomic DNA. Translation: CCD68988.1.
PIRiT15205.
RefSeqiNP_491926.1. NM_059525.4.
UniGeneiCel.30369.

3D structure databases

ProteinModelPortaliO01812.
SMRiO01812. Positions 5-134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi37838. 3 interactions.
DIPiDIP-27012N.
IntActiO01812. 2 interactions.
MINTiMINT-1053545.
STRINGi6239.W02D3.5.2.

2D gel databases

World-2DPAGE0020:O01812.

Proteomic databases

EPDiO01812.
PaxDbiO01812.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW02D3.5; W02D3.5; WBGene00002258.
GeneIDi172390.
KEGGicel:CELE_W02D3.5.
UCSCiW02D3.5.3. c. elegans.

Organism-specific databases

CTDi172390.
WormBaseiW02D3.5; CE14426; WBGene00002258; lbp-6.

Phylogenomic databases

eggNOGiKOG4015. Eukaryota.
ENOG4111US8. LUCA.
GeneTreeiENSGT00760000118898.
HOGENOMiHOG000004829.
InParanoidiO01812.
OMAiPDDRHVK.
PhylomeDBiO01812.

Enzyme and pathway databases

ReactomeiR-CEL-163560. Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.
R-CEL-2453902. The canonical retinoid cycle in rods (twilight vision).
R-CEL-5362517. Signaling by Retinoic Acid.
R-CEL-5365859. RA biosynthesis pathway.
R-CEL-975634. Retinoid metabolism and transport.

Miscellaneous databases

PROiO01812.

Family and domain databases

Gene3Di2.40.128.20. 1 hit.
InterProiIPR012674. Calycin.
IPR011038. Calycin-like.
IPR000463. Fatty_acid-bd.
IPR031259. iLBP.
IPR000566. Lipocln_cytosolic_FA-bd_dom.
[Graphical view]
PANTHERiPTHR11955. PTHR11955. 1 hit.
PfamiPF00061. Lipocalin. 1 hit.
[Graphical view]
PRINTSiPR00178. FATTYACIDBP.
SUPFAMiSSF50814. SSF50814. 1 hit.
PROSITEiPS00214. FABP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiFABP6_CAEEL
AccessioniPrimary (citable) accession number: O01812
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: July 1, 1997
Last modified: June 8, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.