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Protein
Submitted name:

AdaPtin, Mu/medium chain (Clathrin associated complex)

Gene

apm-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • apical protein localization Source: WormBase
  • innate immune response Source: WormBase
  • intracellular protein transport Source: InterPro
  • vesicle-mediated transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Enzyme and pathway databases

ReactomeiR-CEL-432720. Lysosome Vesicle Biogenesis.
R-CEL-432722. Golgi Associated Vesicle Biogenesis.
R-CEL-6798695. Neutrophil degranulation.
SignaLinkiO01755.

Names & Taxonomyi

Protein namesi
Submitted name:
AdaPtin, Mu/medium chain (Clathrin associated complex)Imported
Gene namesi
Name:apm-1Imported
ORF Names:CELE_F55A12.7Imported, F55A12.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF55A12.7; CE30145; WBGene00000150; apm-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO01755.
PaxDbiO01755.
PeptideAtlasiO01755.

Expressioni

Gene expression databases

BgeeiWBGene00000150.

Interactioni

Protein-protein interaction databases

STRINGi6239.F55A12.7.

Structurei

3D structure databases

ProteinModelPortaliO01755.
SMRiO01755.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 424MHD (mu homology)InterPro annotationAdd BLAST259

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
GeneTreeiENSGT00530000062779.
HOGENOMiHOG000173247.
InParanoidiO01755.
KOiK12393.
OMAiFITQQGN.
OrthoDBiEOG091G06XI.
PhylomeDBiO01755.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O01755-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSISGLFILD LKGNVVISRN YRGDVDMSCI EKFMPLLVEK EDEGSASPVL
60 70 80 90 100
VHQGISYTYI KYMNVYLVTI SKKNTNVILV LSALYKIVEV FCEYFKTLEE
110 120 130 140 150
EAVRDNFVII YELFDEMLDF GYPQTTESKI LQEFITQQGN RLETVRPPMA
160 170 180 190 200
VTNAVSWRSE GIKYRKNEVF LDVIESVNML ANAQGTVLRS EIVGSIRFRV
210 220 230 240 250
VLSGMPELRL GLNDKVFFQQ SGASSRRGNS GKGVELEDIK FHQCVRLSRF
260 270 280 290 300
DSERTISFIP PDGEFELMSY RLTTQVKPLI WVEAAVERHA HSRVEYMVKA
310 320 330 340 350
KSQFKRQSVA NHVEVIIPVP SDVSAPKFKT GAGTAKYVPE LNAIVWSIRS
360 370 380 390 400
FPGGREYIMR SSFMLPSIGS EELEGRPPIN VKFEIPYYTT SGLQVRYLKI
410 420
IEKSGYQALP WVRYVTQNGD YQMRMT
Length:426
Mass (Da):48,618
Last modified:March 1, 2002 - v2
Checksum:iF18D7EB0D8E15098
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD65442.1.
PIRiT15189.
RefSeqiNP_491572.2. NM_059171.5.
UniGeneiCel.6868.

Genome annotation databases

EnsemblMetazoaiF55A12.7; F55A12.7; WBGene00000150.
GeneIDi172180.
KEGGicel:CELE_F55A12.7.
UCSCiF55A12.7. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD65442.1.
PIRiT15189.
RefSeqiNP_491572.2. NM_059171.5.
UniGeneiCel.6868.

3D structure databases

ProteinModelPortaliO01755.
SMRiO01755.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.F55A12.7.

Proteomic databases

EPDiO01755.
PaxDbiO01755.
PeptideAtlasiO01755.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF55A12.7; F55A12.7; WBGene00000150.
GeneIDi172180.
KEGGicel:CELE_F55A12.7.
UCSCiF55A12.7. c. elegans.

Organism-specific databases

CTDi172180.
WormBaseiF55A12.7; CE30145; WBGene00000150; apm-1.

Phylogenomic databases

eggNOGiKOG0937. Eukaryota.
ENOG410XPFS. LUCA.
GeneTreeiENSGT00530000062779.
HOGENOMiHOG000173247.
InParanoidiO01755.
KOiK12393.
OMAiFITQQGN.
OrthoDBiEOG091G06XI.
PhylomeDBiO01755.

Enzyme and pathway databases

ReactomeiR-CEL-432720. Lysosome Vesicle Biogenesis.
R-CEL-432722. Golgi Associated Vesicle Biogenesis.
R-CEL-6798695. Neutrophil degranulation.
SignaLinkiO01755.

Gene expression databases

BgeeiWBGene00000150.

Family and domain databases

InterProiIPR022775. AP_mu_sigma_su.
IPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
PF01217. Clat_adaptor_s. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00990. CLAT_ADAPTOR_M_1. 1 hit.
PS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO01755_CAEEL
AccessioniPrimary (citable) accession number: O01755
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: March 1, 2002
Last modified: November 30, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.