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O01673 (TPM_ACAVI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 3, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Domain

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similarities

Belongs to the tropomyosin family.

Ontologies

Keywords
   DomainCoiled coil
Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Tropomyosin
PRO_0000205644

Regions

Coiled coil1 – 284284

Sequences

Sequence LengthMass (Da)Tools
O01673 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 885714CB0DF62BAB

FASTA28433,247
        10         20         30         40         50         60 
MDAIKKKMQA MKIEKDTALD RADAAKEKVR QMTDKLERIE EELRDTQKKM MQTENDLNKA 

        70         80         90        100        110        120 
QEDLAVANTN LEDKEKKVQK AEAEVPPLNR RMTLLEEELE RAEERLKIAT DKLEKATHTA 

       130        140        150        160        170        180 
DESDRVRKVM ENRSFQDEER ANTVESQLKE AQLLAEEADR KYDEVARKLA MVEADLERAE 

       190        200        210        220        230        240 
ERAEAGENKI VELEEELRVV GNNLKFLEVS EEKALQREDS YEEQIRTVSA RLKEAETRAE 

       250        260        270        280 
FAERSVQKLQ KEVDRLEDEL VHEKGRYKNI SEELDQTFQE LFGY 

« Hide

References

[1]"Molecular cloning and characterization of tropomyosin, a protective antigen of Acanthocheilonema viteae."
Adam R., Hartmann S., von Nickisch-Rosenegk E., Lucius R.
Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Muscle.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF000607 mRNA. Translation: AAB53807.1.

3D structure databases

ProteinModelPortalO01673.
SMRO01673. Positions 1-282.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR000533. Tropomyosin.
[Graphical view]
PfamPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSPR00194. TROPOMYOSIN.
PROSITEPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPM_ACAVI
AccessionPrimary (citable) accession number: O01673
Entry history
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: July 1, 1997
Last modified: October 3, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families