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Protein
Submitted name:

Myosin light chain kinase isoform-I

Gene

Strn-Mlck

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • calmodulin-dependent protein kinase activity Source: FlyBase
  • myosin light chain kinase activity Source: FlyBase
  • protein serine/threonine kinase activity Source: FlyBase
  • structural constituent of cytoskeleton Source: FlyBase

GO - Biological processi

  • protein phosphorylation Source: FlyBase

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase

Enzyme and pathway databases

ReactomeiR-DME-445355 Smooth Muscle Contraction
R-DME-5627123 RHO GTPases activate PAKs
SignaLinkiO01651

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin light chain kinase isoform-IImported
Gene namesi
Name:Strn-MlckImported
ORF Names:CG44162Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0265045 Strn-Mlck

PTM / Processingi

Proteomic databases

PRIDEiO01651

Expressioni

Gene expression databases

BgeeiFBgn0265045
ExpressionAtlasiO01651 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliO01651
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 158Ig-likeInterPro annotationAdd BLAST116
Domaini162 – 267Fibronectin type-IIIInterPro annotationAdd BLAST106
Domaini294 – 550Protein kinaseInterPro annotationAdd BLAST257

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0613 Eukaryota
KOG3510 Eukaryota
KOG4475 Eukaryota
ENOG410XQFD LUCA
OrthoDBiEOG091G005W

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00041 fn3, 1 hit
PF07679 I-set, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SM00409 IG, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF49265 SSF49265, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS50835 IG_LIKE, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

O01651-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLESYPEN GIRLLRMRDV TASRSGEICL QVKHPQAESR RIPTTRTYTS
60 70 80 90 100
LLVLPAIRGN SSSSSLAARS CILTRPEDCT ALIGGHVRLS VRYEPFPGTK
110 120 130 140 150
VIWYKACHPI VDSSNVTIRT TSQQSTLYIT DISADDSGKY TVEVMNDYGV
160 170 180 190 200
EAAAASVAVE GPPEPPSGQP SVSLGPDRVA VAWCGPPYDG GCMITGFIIE
210 220 230 240 250
MQTIGDENCD EDSWQQVTRV VDSLAYTVKN LQPERQYRFR VRAENIHGRS
260 270 280 290 300
APGQASELVQ ITNTPQRSTS SDASDRFGQA TVSVQSGGDF KSRFEIIEEL
310 320 330 340 350
GKGRFGIVYK VQERGQPEQL LAAKVIKCIK SQDRQKVLEE ISIMRALQHP
360 370 380 390 400
KLLQLAASFE SPREIVMVME YITGGELFER VVADDFTLTE MDCILFLRQV
410 420 430 440 450
CDGVAYMHGQ SVVHLDLKPE NIMCHTRTSH QIKIIDFGLA QRLDTKAPVR
460 470 480 490 500
VLFGTPEFIP PEIISYEPIG FQSDMWSVGV ICYVLLSGLS PFMGDTDVET
510 520 530 540 550
FSNITRADYD YDDEAFDCVS QEAKDFISQL LVHRKEDRLT AQQCLESKWL
560 570 580 590 600
SQRPDDSLSN NKICTDKLKK FIIRRKWQKT GNAIRALGRM ANLSVSRRNS
610 620 630 640 650
AIAMGVLSSP RPSISGLGML TTSAIGGGTS SQMTSLHEEE DDFSGEMPPV
660 670 680 690 700
EKRTVLKLRD KSQCSERSDS GYSECSNCSG AQETLLLSLA KSKLEAIAKA
710 720 730 740 750
STLPTVVHDT EQPVSLELPT KGEAIMRSDF TNTIKMRKKS LEDSAAREKP
760 770 780 790 800
RSKPQVKPLL CESKLKVSQL KDRFQVSPAP ASASASASAA NKPPLAYGPF
810 820 830 840 850
KIAKVASVGR ISRTEEPGRS GRGAPSVSGK GKSPQVRSMP SSPLPQRSAT
860 870 880 890 900
PTQLMSQRVR EAAERLAQQH TVASAQRHLG NGRGTGNGNG NGNSNSNGNG
910 920
NGNTAETNRE SRARRLINRF NSETQHITS
Length:929
Mass (Da):101,924
Last modified:July 1, 1997 - v1
Checksum:i07A29072FFE260A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89661 mRNA Translation: BAA19488.1

Similar proteinsi

Entry informationi

Entry nameiO01651_DROME
AccessioniPrimary (citable) accession number: O01651
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 23, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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