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Protein
Submitted name:

Myosin light chain kinase isoform-I

Gene

Strn-Mlck

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • calmodulin-dependent protein kinase activity Source: FlyBase
  • myosin light chain kinase activity Source: FlyBase
  • protein serine/threonine kinase activity Source: FlyBase
  • structural constituent of cytoskeleton Source: FlyBase

GO - Biological processi

  • protein phosphorylation Source: FlyBase
  • regulation of glucose metabolic process Source: FlyBase

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase

Enzyme and pathway databases

ReactomeiR-DME-445355. Smooth Muscle Contraction.
R-DME-5627123. RHO GTPases activate PAKs.
SignaLinkiO01651.

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin light chain kinase isoform-IImported
Gene namesi
Name:Strn-MlckImported
ORF Names:CG44162Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0265045. Strn-Mlck.

PTM / Processingi

Proteomic databases

PaxDbiO01651.
PRIDEiO01651.

Expressioni

Gene expression databases

BgeeiFBgn0265045.
ExpressionAtlasiO01651. differential.

Structurei

3D structure databases

ProteinModelPortaliO01651.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 158Ig-likeInterPro annotationAdd BLAST116
Domaini162 – 267Fibronectin type-IIIInterPro annotationAdd BLAST106
Domaini294 – 550Protein kinaseInterPro annotationAdd BLAST257

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0613. Eukaryota.
KOG3510. Eukaryota.
KOG4475. Eukaryota.
ENOG410XQFD. LUCA.
OrthoDBiEOG091G005W.

Family and domain databases

CDDicd00063. FN3. 1 hit.
Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00041. fn3. 1 hit.
PF07679. I-set. 1 hit.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00060. FN3. 1 hit.
SM00409. IG. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF49265. SSF49265. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 1 hit.
PS50835. IG_LIKE. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

O01651-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLESYPEN GIRLLRMRDV TASRSGEICL QVKHPQAESR RIPTTRTYTS
60 70 80 90 100
LLVLPAIRGN SSSSSLAARS CILTRPEDCT ALIGGHVRLS VRYEPFPGTK
110 120 130 140 150
VIWYKACHPI VDSSNVTIRT TSQQSTLYIT DISADDSGKY TVEVMNDYGV
160 170 180 190 200
EAAAASVAVE GPPEPPSGQP SVSLGPDRVA VAWCGPPYDG GCMITGFIIE
210 220 230 240 250
MQTIGDENCD EDSWQQVTRV VDSLAYTVKN LQPERQYRFR VRAENIHGRS
260 270 280 290 300
APGQASELVQ ITNTPQRSTS SDASDRFGQA TVSVQSGGDF KSRFEIIEEL
310 320 330 340 350
GKGRFGIVYK VQERGQPEQL LAAKVIKCIK SQDRQKVLEE ISIMRALQHP
360 370 380 390 400
KLLQLAASFE SPREIVMVME YITGGELFER VVADDFTLTE MDCILFLRQV
410 420 430 440 450
CDGVAYMHGQ SVVHLDLKPE NIMCHTRTSH QIKIIDFGLA QRLDTKAPVR
460 470 480 490 500
VLFGTPEFIP PEIISYEPIG FQSDMWSVGV ICYVLLSGLS PFMGDTDVET
510 520 530 540 550
FSNITRADYD YDDEAFDCVS QEAKDFISQL LVHRKEDRLT AQQCLESKWL
560 570 580 590 600
SQRPDDSLSN NKICTDKLKK FIIRRKWQKT GNAIRALGRM ANLSVSRRNS
610 620 630 640 650
AIAMGVLSSP RPSISGLGML TTSAIGGGTS SQMTSLHEEE DDFSGEMPPV
660 670 680 690 700
EKRTVLKLRD KSQCSERSDS GYSECSNCSG AQETLLLSLA KSKLEAIAKA
710 720 730 740 750
STLPTVVHDT EQPVSLELPT KGEAIMRSDF TNTIKMRKKS LEDSAAREKP
760 770 780 790 800
RSKPQVKPLL CESKLKVSQL KDRFQVSPAP ASASASASAA NKPPLAYGPF
810 820 830 840 850
KIAKVASVGR ISRTEEPGRS GRGAPSVSGK GKSPQVRSMP SSPLPQRSAT
860 870 880 890 900
PTQLMSQRVR EAAERLAQQH TVASAQRHLG NGRGTGNGNG NGNSNSNGNG
910 920
NGNTAETNRE SRARRLINRF NSETQHITS
Length:929
Mass (Da):101,924
Last modified:July 1, 1997 - v1
Checksum:i07A29072FFE260A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89661 mRNA. Translation: BAA19488.1.

Similar proteinsi

Entry informationi

Entry nameiO01651_DROME
AccessioniPrimary (citable) accession number: O01651
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: September 27, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)