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Protein
Submitted name:

TYRosinase

Gene

tyr-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TYRosinaseImported
Gene namesi
Name:tyr-4Imported
ORF Names:C34G6.2Imported, CELE_C34G6.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC34G6.2; CE08574; WBGene00016419; tyr-4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500415666519 – 751Sequence analysisAdd BLAST733

Proteomic databases

EPDiO01497.
PaxDbiO01497.
PeptideAtlasiO01497.

Expressioni

Gene expression databases

BgeeiWBGene00016419.

Interactioni

Protein-protein interaction databases

DIPiDIP-24676N.
IntActiO01497. 3 interactors.
MINTiMINT-1098269.
STRINGi6239.C34G6.2.

Structurei

3D structure databases

ProteinModelPortaliO01497.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini458 – 492ShKTInterPro annotationAdd BLAST35
Domaini502 – 536ShKTInterPro annotationAdd BLAST35
Domaini568 – 602ShKTInterPro annotationAdd BLAST35
Domaini612 – 645ShKTInterPro annotationAdd BLAST34

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IEZU. Eukaryota.
ENOG410Y42I. LUCA.
GeneTreeiENSGT00510000050704.
HOGENOMiHOG000017279.
InParanoidiO01497.
KOiK00505.
OMAiLEYTHGN.
OrthoDBiEOG091G02R0.
PhylomeDBiO01497.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR003582. ShKT_dom.
IPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF01549. ShK. 4 hits.
PF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SMARTiSM00254. ShKT. 4 hits.
[Graphical view]
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS51670. SHKT. 4 hits.
PS00497. TYROSINASE_1. 1 hit.
PS00498. TYROSINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O01497-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFLIPIIFT TLPLCLQAQE DPCASAPSEA AKIMCKQIHR WDDGARAASK
60 70 80 90 100
KKKIALPPGM AKGMAAEFAP IASNIYQCMD LPCLCSYLRG TASGNGCTLP
110 120 130 140 150
NGRPLQKSVR KEYRTLTDDE RNRLHAAFRA LKNNGEYERI GRIHSQMSAA
160 170 180 190 200
GGAHSGPAFL PWHREFVKRV EFALRQVDPT VNLPYWDSTL DSRLPRPADT
210 220 230 240 250
IMFSDYLMGS TGLVNDGPFT NWRTLAGRAQ ILRAVGAQGA PLSQNDIDFV
260 270 280 290 300
MRQTQIDQVL SFTAPQQGCP YRTDFNCLEY THGNVHIFVG GDMFDTATSS
310 320 330 340 350
NDPSFFLHHA FIDFVWEEWR LARQSRADRE IAFPPDNQLC ASAQHFGASP
360 370 380 390 400
MQPFSPMRNI DGLSNKYTDN LYSYAPRPTC QAGGDCGSKF LFCDTSTGAA
410 420 430 440 450
RCVSRIRPGS QCGQFRVNPC FSGICQNGVC VLSSTAPRPT PAPTTPTPQN
460 470 480 490 500
PVQSQESCFN ENQCCASWAA SGECSRNTAY MNEWCKASCG VCKPKYRLAD
510 520 530 540 550
DCTDRHTQCS SWSRSGECTK NQLWMTENCR KSCNKCGRSR AQECGGGGTT
560 570 580 590 600
VTTTTPAPAQ QCDNSDGCFN ENVCCAVWGL MGECRKNTRY MACNCRVSCG
610 620 630 640 650
HCYPEDYNYG SCVDYHRSCA GWARVGECQK NPWMAENCRS SCNSCYTQSE
660 670 680 690 700
LRRMCGTTAG SVAPVAQVRQ TNPSRQPPRG GWGRDDFGDN GGWGGNGGGG
710 720 730 740 750
WGNNDPWGGS RWGGGRGGWG GGGWGGGGWG KRSIRAANAS ISMPSFDPDL

L
Length:751
Mass (Da):82,177
Last modified:July 1, 1997 - v1
Checksum:i064874517FE47EAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD66683.1.
PIRiF87789.
RefSeqiNP_491709.1. NM_059308.6.
UniGeneiCel.19158.

Genome annotation databases

EnsemblMetazoaiC34G6.2; C34G6.2; WBGene00016419.
GeneIDi172263.
KEGGicel:CELE_C34G6.2.
UCSCiC34G6.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD66683.1.
PIRiF87789.
RefSeqiNP_491709.1. NM_059308.6.
UniGeneiCel.19158.

3D structure databases

ProteinModelPortaliO01497.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-24676N.
IntActiO01497. 3 interactors.
MINTiMINT-1098269.
STRINGi6239.C34G6.2.

Proteomic databases

EPDiO01497.
PaxDbiO01497.
PeptideAtlasiO01497.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC34G6.2; C34G6.2; WBGene00016419.
GeneIDi172263.
KEGGicel:CELE_C34G6.2.
UCSCiC34G6.2. c. elegans.

Organism-specific databases

CTDi172263.
WormBaseiC34G6.2; CE08574; WBGene00016419; tyr-4.

Phylogenomic databases

eggNOGiENOG410IEZU. Eukaryota.
ENOG410Y42I. LUCA.
GeneTreeiENSGT00510000050704.
HOGENOMiHOG000017279.
InParanoidiO01497.
KOiK00505.
OMAiLEYTHGN.
OrthoDBiEOG091G02R0.
PhylomeDBiO01497.

Gene expression databases

BgeeiWBGene00016419.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR003582. ShKT_dom.
IPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF01549. ShK. 4 hits.
PF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SMARTiSM00254. ShKT. 4 hits.
[Graphical view]
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS51670. SHKT. 4 hits.
PS00497. TYROSINASE_1. 1 hit.
PS00498. TYROSINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO01497_CAEEL
AccessioniPrimary (citable) accession number: O01497
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 2, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.