ID   O01462_CAEEL            Unreviewed;       375 AA.
AC   O01462;
DT   01-JUL-1997, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 2.
DT   16-JUN-2009, entry version 62.
DE   SubName: Full=Serine or cysteine protease inhibitor;
DE   SubName: Full=Serpin protein 6;
GN   Name=srp-6; ORFNames=C03G6.19;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;
OC   Rhabditidae; Peloderinae; Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   MEDLINE=99069613; PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for
RT   investigating biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   GLYCOSYLATION AT ASN-79, AND MASS SPECTROMETRY.
RX   MEDLINE=22660474; PubMed=12754521; DOI=10.1038/nbt829;
RA   Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J.,
RA   Kasai K., Takahashi N., Isobe T.;
RT   "Lectin affinity capture, isotope-coded tagging and mass spectrometry
RT   to identify N-linked glycoproteins.";
RL   Nat. Biotechnol. 21:667-672(2003).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
RX   PubMed=17761667; DOI=10.1074/mcp.M600392-MCP200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
RN   [4]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=14739286; DOI=10.1074/jbc.M400261200;
RA   Pak S.C., Kumar V., Tsu C., Luke C.J., Askew Y.S., Askew D.J.,
RA   Mills D.R., Bromme D., Silverman G.A.;
RT   "SRP-2 is a cross-class inhibitor that participates in postembryonic
RT   development of the nematode Caenorhabditis elegans: initial
RT   characterization of the clade L serpins.";
RL   J. Biol. Chem. 279:15448-15459(2004).
CC   -!- SIMILARITY: Belongs to the serpin family.
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DR   EMBL; U97008; AAB52318.2; -; Genomic_DNA.
DR   EMBL; AY525082; AAS13530.1; -; mRNA.
DR   PIR; T25504; T25504.
DR   RefSeq; NP_504890.1; -.
DR   UniGene; Cel.34274; -.
DR   HSSP; P01012; 1OVA.
DR   IntAct; O01462; 4.
DR   Ensembl; C03G6.19; Caenorhabditis elegans.
DR   GeneID; 179125; -.
DR   KEGG; cel:C03G6.19; -.
DR   NMPDR; fig|6239.3.peg.18445; -.
DR   WormBase; WBGene00005647; srp-6.
DR   WormPep; C03G6.19; CE27579.
DR   OMA; O01462; VIANNAI.
DR   NextBio; 904030; -.
DR   ArrayExpress; O01462; -.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   InterPro; IPR000215; Protease_inhib_I4_serpin.
DR   PANTHER; PTHR11461; Prot_inh_serpin; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Hydrolase; Protease.
SQ   SEQUENCE   375 AA;  41696 MW;  BEFE7D31BEF0275E CRC64;
     MSDSSSDEKM GLLLHSETDF GLSLLRQQNL TESFVFSPLS IALALSLVHV AAKGETRDEI
     RKALLNGATD EELEQHFSNI SAGLLVAEKG TEVNVANHIF SRKTFTIKKL YLNDVKKLYN
     AGASQLNFED QEASAEAINN FVSENTKGHI KKIINPDSIS EELVAVLTNA FYFKANWQTK
     FKKESTYKRE FFSSENSKRE TEFLHSRNSN RKYSENGQFQ VLSLPYKDTS FALSIFLPKT
     RFGLSEALQN LDSVTIQQLM SNTSNTLVNI AMPKWKIETA LGLNRALMAV GIEKAFTDSA
     DLSNFADGIY ISQAAHKALI EVDEDGTVAA AATTISFSLT SVFIPAEEPI EFTADHPFLF
     ILSKDNHPLF IGIHN
//