Unreviewed, UniProtKB/TrEMBL O01462 (O01462_CAEEL)

Names and origin

Protein names

Submitted name:
    Serine or cysteine protease inhibitor EMBL AAS13530.1
Submitted name:
    Serpin protein 6 EMBL AAB52318.2

Gene names

Name:	srp-6 EMBL AAB52318.2 WormBase WBGene00005647 WormPep C03G6.19
ORF Names:	C03G6.19 EMBL AAB52318.2 WormPep C03G6.19

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	375 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the serpin family. RuleBase RU000411V1

Ontologies

Keywords
Molecular function	Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from physical interaction. Source: IntAct serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O01462-1 [UniParc]. Last modified October 1, 2001. Version 2. Checksum: BEFE7D31BEF0275E	FASTA	375	41,696
	10 20 30 40 50 60 MSDSSSDEKM GLLLHSETDF GLSLLRQQNL TESFVFSPLS IALALSLVHV AAKGETRDEI 70 80 90 100 110 120 RKALLNGATD EELEQHFSNI SAGLLVAEKG TEVNVANHIF SRKTFTIKKL YLNDVKKLYN 130 140 150 160 170 180 AGASQLNFED QEASAEAINN FVSENTKGHI KKIINPDSIS EELVAVLTNA FYFKANWQTK 190 200 210 220 230 240 FKKESTYKRE FFSSENSKRE TEFLHSRNSN RKYSENGQFQ VLSLPYKDTS FALSIFLPKT 250 260 270 280 290 300 RFGLSEALQN LDSVTIQQLM SNTSNTLVNI AMPKWKIETA LGLNRALMAV GIEKAFTDSA 310 320 330 340 350 360 DLSNFADGIY ISQAAHKALI EVDEDGTVAA AATTISFSLT SVFIPAEEPI EFTADHPFLF 370 ILSKDNHPLF IGIHN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	"Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins." Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J., Kasai K., Takahashi N., Isobe T. Nat. Biotechnol. 21:667-672(2003) [PubMed: 12754521] [Abstract] Cited for: GLYCOSYLATION AT ASN-79, MASS SPECTROMETRY.
[3]	"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins." Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T. Mol. Cell. Proteomics 6:2100-2109(2007) [PubMed: 17761667] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[4]	"SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins." Pak S.C., Kumar V., Tsu C., Luke C.J., Askew Y.S., Askew D.J., Mills D.R., Bromme D., Silverman G.A. J. Biol. Chem. 279:15448-15459(2004) [PubMed: 14739286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U97008 Genomic DNA. Translation: AAB52318.2. AY525082 mRNA. Translation: AAS13530.1.
PIR	T25504.
RefSeq	NP_504890.1.
UniGene	Cel.34274
3D structure databases
HSSP	HSSP built from PDB template 1OVA based on UniProtKB P01012.
ModBase	Search...
Protein-protein interaction databases
IntAct	O01462. 4 interactions.
Genome annotation databases
Ensembl	C03G6.19. Caenorhabditis elegans. [Contig view]
GeneID	179125.
KEGG	cel:C03G6.19.
NMPDR	fig|6239.3.peg.18445.
Organism-specific databases
WormBase	WBGene00005647. srp-6.
WormPep	C03G6.19. CE27579. [WorfDB]
Phylogenomic databases
OMA	O01462. VIANNAI.
Gene expression databases
ArrayExpress	O01462.
Family and domain databases
InterPro	IPR000215. Protease_inhib_I4_serpin. [Graphical view]
PANTHER	PTHR11461. Prot_inh_serpin. 1 hit.
Pfam	PF00079. Serpin. 1 hit. [Graphical view]
SMART	SM00093. SERPIN. 1 hit. [Graphical view]
PROSITE	PS00284. SERPIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	904030.

Entry information

Entry name

O01462_CAEEL

Accession

Primary (citable) accession number: O01462

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	October 1, 2001
Last modified:	June 16, 2009
This is version 62 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)