O01385 (O01385_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tpr homolog EMBL AAC47506.1

Gene names

Name:	Mtor FlyBase FBgn0013756
ORF Names:	CG8274 FlyBase FBgn0013756

Organism

Drosophila melanogaster (Fruit fly) EMBL AAC47506.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	2346 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	protein import into nucleus Inferred from electronic annotation. Source: InterPro spindle assembly Inferred from direct assay. Source: FlyBase
Cellular component	nuclear pore Inferred from direct assay Ref.1. Source: FlyBase spindle midzone Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O01385 [UniParc]. Last modified July 1, 1997. Version 1. Checksum: B44FDA6000B68934	FASTA	2,346	262,365
	10 20 30 40 50 60 MDLSGPQTLN NILQPDELKL VPEDVQKKLS EYINNFSDEY CKNRAAANRL AEAEQKKEEL 70 80 90 100 110 120 ENKMEDYLVK FTSFELNVNE LRTHLDQMSS ERVNLMDTIA KGEQTISQLR KEKASVVEER 130 140 150 160 170 180 DSMMKVIERQ QAELERLKQD LHTYQQQLSS AIAAKCEAIA RVDEIQSKEV ALELKENRME 190 200 210 220 230 240 SERDMLHKEI LLISGDLNKS NAELQNIRRE HTINTMQLQS CLKEKTESLK LMQEQYEQAV 250 260 270 280 290 300 KTIGELTSKI EMQNDTAFKQ NQATEEYVGK LKKELDAKEK LFEIFKSTES DHLIQREELL 310 320 330 340 350 360 QGISEIKRLL EEAEEQCAQL TEQMETMKQK HSAELDEQNK KIQAMEQELA SANDLLKQAR 370 380 390 400 410 420 ESNLESAICQ LAPSAAVASR LIRSDLSLTE LYSMYAKSSE ELEMRNCEIE QLKLQLKSII 430 440 450 460 470 480 AEISESAPIL EKQNSDYQKM KETNSELLRE HDELLQNKLC LERELERALS TLNHNQNENK 490 500 510 520 530 540 KLKQTHTDLS RQVCMLLDEL NCIRAGVKHV RIQPTRQLPT SESLISDNLV TFSSIEELVD 550 560 570 580 590 600 RNTYLLNMSR ELTELLEASE KNQDKMLLEQ SKNHIRKLDA RFAELEDLLT QKNNTVTTLL 610 620 630 640 650 660 SKCDRYKKLY FAAQKKLGQN TVDLDDSNLE PNDSALDTSE QPAANFEKSR KLEKRVRQLE 670 680 690 700 710 720 QQLEGEVKKY ASLKENYDYY TSEKRKNDAL AQEQFDSMRK EVRGLTSSNC KLMNTTEFQK 730 740 750 760 770 780 EQIELLHTNI GTYKQQVTTL EERTKNYEKT IIKHEQTVHL LKDEMMAAHR KHAAADAEAQ 790 800 810 820 830 840 SLRQENRILR DTSSRLQIEK ETYHREQQSQ SLLLNSLEFI KTNLERSEME GRQRLEQRLD 850 860 870 880 890 900 DTVRELAAQR RHFQEEEEKF RESINEFKRQ AETAIKLKDE EKQLADKWQA ELTSVREELA 910 920 930 940 950 960 EKVNKVNELS KKLQEVLTPT LNDNHITAAN KRAREFELKL DQATVVIESL TKELAKTREH 970 980 990 1000 1010 1020 GEQFYKMSQS AESEIKRLHE LHGELVSKQE EEIKKLRSSE AELKTRISDL EAEAMLSNVT 1030 1040 1050 1060 1070 1080 EQSKTVNQSG QLKSAQDDLK SLLEKLTEAN CTIRTLRSEN TSLVESLNAA EVKYANGMIQ 1090 1100 1110 1120 1130 1140 HSADIQELTR YKAEFFKAND ELNQLKSGRE SLQAAYDELL RSNAEAQKLL DKEREESEKR 1150 1160 1170 1180 1190 1200 VSDLHALNSN LHDQIEALAS KLAVLASQSQ NPNSSLNESA MDGDQSLNAS GLTAAEEGRN 1210 1220 1230 1240 1250 1260 NEQLLKIIKF LRKEKDLFAA KLDILKAENA RLISEHAIQQ KKVDELNGYL NQERAKSQTD 1270 1280 1290 1300 1310 1320 VVSANKHEEV LRKIETLNAI TDSNRILREE RNALTLRVAE LTDRISSVEK ELFPLQCSNK 1330 1340 1350 1360 1370 1380 ELTSKIEEIN VENTSLRTEA IKWRQRANAL VEKSNRNPEE FKRLQAEREH LAKLLTAEKE 1390 1400 1410 1420 1430 1440 LNKKQSDELT VLKQRMNTEI PMLNKQMQIL DEARKKQVDE FTNLKQNNTR QTQDIMELKN 1450 1460 1470 1480 1490 1500 RLLQKEEELL KANEELETKD KTIADKETKE LQLRKLAKRY KDFYIGLQSQ GGGTESAAEL 1510 1520 1530 1540 1550 1560 EKVRSELEEV NNQLRALKDE HEKITKECDE VKKRTEPETD TSAIRQEYKA KLDKLVVDLT 1570 1580 1590 1600 1610 1620 VARTDLVNQE TTFAGTKSSY DETIARLEKE LQENIVANKD INQRLTRENE SLHMRINQLT 1630 1640 1650 1660 1670 1680 RQLGSQQSTK PSTSSVAEKG NISESSPRTA NVKPMSGSAT VQQSATVTPW RGGETPLASI 1690 1700 1710 1720 1730 1740 RPISVQNSRT AAILPTSQQP PAGSSTSTSS SSSSSSTSTT SAAGGGSSAV AQTALVPPQQ 1750 1760 1770 1780 1790 1800 QVHTTGSAAL ESMASSSPTS SHTDYMPSTS SASVAVAAIP PMGASSAAES SQEAESIQHP 1810 1820 1830 1840 1850 1860 QQNDSQLFVG GAQQQVVALV SPRVEGSSSS SSSTSVPTAT APSIQDGGSQ SQQPSTSGSS 1870 1880 1890 1900 1910 1920 SSSSTVVSSH SRHTPSSSNV TTTQAGCSLQ GIKRPRDIEG DSSTGTEEGV AEKMSKITKR 1930 1940 1950 1960 1970 1980 LRGPMHSGEL SAGHIGDSGM DVDQMPTSSQ RDQEDDIQVV DSDDEEDVLA DADDGPIDGG 1990 2000 2010 2020 2030 2040 EAEQEGYEDS YEQDNEMDDN EGGDDDNDIA VDAQDNNEVD IEVPEQHMQA QEESQSLDNQ 2050 2060 2070 2080 2090 2100 AIATASASTQ ENNQSQATTS GSGESSNPVT LPQAEASNWK QAAASTSTAA ARRNESSVEI 2110 2120 2130 2140 2150 2160 VSSPQVSNFC EQPARLESAE VDGTAEVAGG APHESAGPSD TGAASVSSPQ KQSEAGESSG 2170 2180 2190 2200 2210 2220 SDALKAADDG GDHADGTDNA READEAFAEE TMATGQGEDS QPLGNDNPNV GTSQSEVSHN 2230 2240 2250 2260 2270 2280 QANLGEGNPT EDSEGADGVS SEGEKQAVGV EEEGREAEAT SPSENTRFRT LRSAVPTRRG 2290 2300 2310 2320 2330 2340 HRAMRGGSPN SQNRPQRIVW QRDTSPGNIQ QNQMSANNNR FAQRTRNRRP IRRPPPNNFN NGGRFP

References

[1]	"A Drosophila Tpr protein homolog is localized both in the extrachromosomal channel network and to nuclear pore complexes." Zimowska G., Aris J.P., Paddy M.R. J. Cell Sci. 110:927-944(1997) [PubMed: 9152019] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U91980 mRNA. Translation: AAC47506.1.
PIR	T13829.
3D structure databases
ProteinModelPortal	O01385.
ModBase	Search...
Protein-protein interaction databases
STRING	O01385.
Proteomic databases
PRIDE	O01385.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0013756. Mtor.
Phylogenomic databases
eggNOG	inNOG06033.
InParanoid	O01385.
Gene expression databases
ArrayExpress	O01385.
Bgee	O01385.
Family and domain databases
InterPro	IPR012929. TPR_MLP1_2. [Graphical view]
Pfam	PF07926. TPR_MLP1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O01385_DROME

Accession

Primary (citable) accession number: O01385

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 1997
Last sequence update:	July 1, 1997
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)