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Protein
Submitted name:

Klu protein

Gene

klu

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • larval feeding behavior Source: FlyBase
  • negative regulation of Ras protein signal transduction Source: FlyBase
  • neuroblast development Source: FlyBase
  • neurogenesis Source: FlyBase
  • neuronal stem cell population maintenance Source: FlyBase
  • positive regulation of compound eye retinal cell programmed cell death Source: FlyBase
  • positive regulation of neuroblast proliferation Source: FlyBase
  • regulation of stem cell division Source: FlyBase
  • sensory organ precursor cell fate determination Source: FlyBase
  • tricarboxylic acid cycle Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Klu proteinImported
Gene namesi
Name:kluImported
ORF Names:CG12296Imported
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0013469. klu.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: FlyBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO01348.
PRIDEiO01348.

Expressioni

Gene expression databases

BgeeiFBgn0013469.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0303113.

Structurei

3D structure databases

ProteinModelPortaliO01348.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini589 – 617C2H2-typeInterPro annotationAdd BLAST29
Domaini625 – 652C2H2-typeInterPro annotationAdd BLAST28
Domaini653 – 680C2H2-typeInterPro annotationAdd BLAST28
Domaini681 – 708C2H2-typeInterPro annotationAdd BLAST28

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OrthoDBiEOG091G0Y91.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O01348-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMAEGTDPM GHGHHTNPHN PPQQPPQHHP HHLPLPHPPP APPPQLLNFN
60 70 80 90 100
HHQQQYLPHM YPAAAAAAQS HSHYGGLQYP HPHALQHQHH PHQHQHHLPL
110 120 130 140 150
ALSLHQQAAA AAAVAAAVAT NHSNNNNQAS VANNNIVVPW KQRKRKRLSA
160 170 180 190 200
VLDKLHHNNN NNNNNNNETH SNGMACKAEP MEMKGDLAED AEQDEDHDGS
210 220 230 240 250
VPDEEDDSVD HDGDAGKYIK SEQPVSEDEE NEQEMDQDIE DISGEDLELS
260 270 280 290 300
HSDDNDQDDS PRISMSPLQL QAAQSNLPQD QNQPMNKENP LHVDIKTEIP
310 320 330 340 350
SPYDRYFPIP SPLFGYYLHT KYLNEVFRRR HDLYPSPLQH TPSSIASETE
360 370 380 390 400
TSPNAQERKS SSNHVLPHAL LANNSPPPSL PSPPRSESSV TNNVATTTTS
410 420 430 440 450
STTKKRTSPK PKGKKGDKKP MPPPQERPLD LCMRNEVEPK KYKKSGSKSS
460 470 480 490 500
LESRSAGMMP PPPALSAASS LESMSALSPA SSSHSGHMPI TSAATPNHQP
510 520 530 540 550
PPNSPYANAM NAAHGGTAAA AAMIKMEMPL HPLHHQQMHH SQVPTTTVGV
560 570 580 590 600
PVIKGDVASP TTKETVAWRY NLDVSPVVEE MPPGSDVAYV CPTCGQMFSL
610 620 630 640 650
HDRLAKHMAS RHKSRNPAND IAKAYSCDVC RRSFARSDML TRHMRLHTGV
660 670 680 690 700
KPYTCKVCGQ VFSRSDHLST HQRTHTGEKP YKCPQCPYAA CRRDMITRHM
710 720 730 740 750
RTHTRYDSRG GSREGREGRE GREGKESAIR AGATSESRSP TRPVPIRCWT
Length:750
Mass (Da):82,855
Last modified:July 1, 1997 - v1
Checksum:iBEA21889F21ED3A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11066 mRNA. Translation: CAA71945.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11066 mRNA. Translation: CAA71945.1.

3D structure databases

ProteinModelPortaliO01348.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0303113.

Proteomic databases

PaxDbiO01348.
PRIDEiO01348.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0013469. klu.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
OrthoDBiEOG091G0Y91.

Miscellaneous databases

ChiTaRSiklu. fly.

Gene expression databases

BgeeiFBgn0013469.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO01348_DROME
AccessioniPrimary (citable) accession number: O01348
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: November 30, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.