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O00940

- PGK_CONMG

UniProt

O00940 - PGK_CONMG

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Protein

Phosphoglycerate kinase

Gene

PGK

Organism
Condylostoma magnum
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei17 – 171SubstrateBy similarity
Binding sitei100 – 1001SubstrateBy similarity
Binding sitei148 – 1481SubstrateBy similarity
Binding sitei197 – 1971ATPBy similarity
Binding sitei288 – 2881ATP; via carbonyl oxygenBy similarity
Binding sitei319 – 3191ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi349 – 3524ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGK
OrganismiCondylostoma magnum
Taxonomic identifieri40633 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraPostciliodesmatophoraHeterotricheaHeterotrichidaCondylostomatidaeCondylostoma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›378›378Phosphoglycerate kinasePRO_0000145847Add
BLAST

Proteomic databases

PRIDEiO00940.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO00940.
SMRiO00940. Positions 1-376.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2 – 43Substrate bindingBy similarity
Regioni41 – 444Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Fragment.

O00940-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
VDFNVPIKDG RITDSNRIQA TLPSIQAVLD NGAKSLVLMS HLGRPDGRRD
60 70 80 90 100
EKSSLRPVAE QLQTLLGRPV TFLEDCVGPE IESACADPAP GSVFLLENLR
110 120 130 140 150
FHPEEEGAGV DESGNKFKPS QEQVQTFRDS LTRLGDVYIN DAFGTAHRAH
160 170 180 190 200
SSMAGINLPQ RAAGYLMGKE LEYFSRALEN PNRPLLVIMG GAKVSDKIQL
210 220 230 240 250
INNLLDNCNE MIIAGGMAFT FKKVLDNLEI GNSLFDEAGA KIVQGIIDKA
260 270 280 290 300
AERHVQIHLP TDFVCGDKFE TGCNVQTYSG NIPEGFMGLD IGPELQEAMA
310 320 330 340 350
QAIQRAETIV WNGPPGVFEI PEFRAGSERF FREIVAATRD RRVVSIVGGG
360 370
DTAAFAKTMG DESDVISHIS TGGGASDP
Length:378
Mass (Da):40,900
Last modified:July 1, 1997 - v1
Checksum:i0422A6693EE1328C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei378 – 3781

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U97356 Genomic DNA. Translation: AAB58163.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U97356 Genomic DNA. Translation: AAB58163.1 .

3D structure databases

ProteinModelPortali O00940.
SMRi O00940. Positions 1-376.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi O00940.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Pearlman R.E.
    Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPGK_CONMG
AccessioniPrimary (citable) accession number: O00940
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: October 1, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3