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O00940

- PGK_CONMG

UniProt

O00940 - PGK_CONMG

Protein

Phosphoglycerate kinase

Gene

PGK

Organism
Condylostoma magnum
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei17 – 171SubstrateBy similarity
    Binding sitei100 – 1001SubstrateBy similarity
    Binding sitei148 – 1481SubstrateBy similarity
    Binding sitei197 – 1971ATPBy similarity
    Binding sitei288 – 2881ATP; via carbonyl oxygenBy similarity
    Binding sitei319 – 3191ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi349 – 3524ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:PGK
    OrganismiCondylostoma magnum
    Taxonomic identifieri40633 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraPostciliodesmatophoraHeterotricheaHeterotrichidaCondylostomatidaeCondylostoma

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›378›378Phosphoglycerate kinasePRO_0000145847Add
    BLAST

    Proteomic databases

    PRIDEiO00940.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO00940.
    SMRiO00940. Positions 1-376.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni2 – 43Substrate bindingBy similarity
    Regioni41 – 444Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O00940-1 [UniParc]FASTAAdd to Basket

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    VDFNVPIKDG RITDSNRIQA TLPSIQAVLD NGAKSLVLMS HLGRPDGRRD    50
    EKSSLRPVAE QLQTLLGRPV TFLEDCVGPE IESACADPAP GSVFLLENLR 100
    FHPEEEGAGV DESGNKFKPS QEQVQTFRDS LTRLGDVYIN DAFGTAHRAH 150
    SSMAGINLPQ RAAGYLMGKE LEYFSRALEN PNRPLLVIMG GAKVSDKIQL 200
    INNLLDNCNE MIIAGGMAFT FKKVLDNLEI GNSLFDEAGA KIVQGIIDKA 250
    AERHVQIHLP TDFVCGDKFE TGCNVQTYSG NIPEGFMGLD IGPELQEAMA 300
    QAIQRAETIV WNGPPGVFEI PEFRAGSERF FREIVAATRD RRVVSIVGGG 350
    DTAAFAKTMG DESDVISHIS TGGGASDP 378
    Length:378
    Mass (Da):40,900
    Last modified:July 1, 1997 - v1
    Checksum:i0422A6693EE1328C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-terminal residuei378 – 3781

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U97356 Genomic DNA. Translation: AAB58163.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U97356 Genomic DNA. Translation: AAB58163.1 .

    3D structure databases

    ProteinModelPortali O00940.
    SMRi O00940. Positions 1-376.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O00940.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Pearlman R.E.
      Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiPGK_CONMG
    AccessioniPrimary (citable) accession number: O00940
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3