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Protein

Actin

Gene
N/A
Organism
Sterkiella cavicola (Ciliate) (Histriculus cavicola)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Actin
OrganismiSterkiella cavicola (Ciliate) (Histriculus cavicola)
Taxonomic identifieri742176 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataSpirotricheaStichotrichiaSporadotrichidaOxytrichidaeStylonychinaeSterkiella

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 375375ActinPRO_0000088949Add
BLAST

Proteomic databases

PRIDEiO00937.

Structurei

3D structure databases

ProteinModelPortaliO00937.
SMRiO00937. Positions 8-374.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O00937-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQQTCVID NGSGVVKAGF SGEDAPRAVY PSIVGRPKNV SALIGVDSAS
60 70 80 90 100
EYLGDEAQQK RGVLKIFYPI EHGIVKDWDD MEKIWNHTFY VELRVSPDEH
110 120 130 140 150
PVLLTEAPLN PKVNREKMTQ IMFETFNVPA LYVAIQAVLS LYSAGRTTGI
160 170 180 190 200
VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA GRDLTTFMAK LLTERGYSFT
210 220 230 240 250
SSAELEIVRD IKEKLCFVAL DYEAALKQSH DSSTFEKNYE LPDGKIITIG
260 270 280 290 300
SERFRCPEYL FKPLEMNGKE LDSIQDLTYK SIQECDVDVR RDLYQTIILS
310 320 330 340 350
GGSTSIEGIG ERLLKEIENR APKSINVKVI ASPDRRFAVW RGGSTLTSLS
360 370
TFASMWITKE DYDENGASIV HRKCI
Length:375
Mass (Da):41,853
Last modified:January 1, 1999 - v2
Checksum:iEAA9A2EA82316BDC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12047 Genomic DNA. Translation: CAA72778.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12047 Genomic DNA. Translation: CAA72778.1.

3D structure databases

ProteinModelPortaliO00937.
SMRiO00937. Positions 8-374.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO00937.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Actin of Histriculus cavicola: characteristics of the highly divergent hypotrich ciliate actins."
    Perez-Romero P., Villalobo E., Diaz-Ramos C., Calvo P., Torres A.
    J. Eukaryot. Microbiol. 46:469-472(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiACT_STECV
AccessioniPrimary (citable) accession number: O00937
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 1, 1999
Last modified: October 14, 2015
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.