Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O00871

- PGK_TETPY

UniProt

O00871 - PGK_TETPY

Protein

Phosphoglycerate kinase

Gene

PGK

Organism
Tetrahymena pyriformis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (01 Jul 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei17 – 171SubstrateBy similarity
    Binding sitei100 – 1001SubstrateBy similarity
    Binding sitei148 – 1481SubstrateBy similarity
    Binding sitei197 – 1971ATPBy similarity
    Binding sitei290 – 2901ATP; via carbonyl oxygenBy similarity
    Binding sitei321 – 3211ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi350 – 3534ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:PGK
    OrganismiTetrahymena pyriformis
    Taxonomic identifieri5908 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›375›375Phosphoglycerate kinasePRO_0000145860Add
    BLAST

    Proteomic databases

    PRIDEiO00871.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO00871.
    SMRiO00871. Positions 1-374.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni2 – 43Substrate bindingBy similarity
    Regioni41 – 444Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O00871-1 [UniParc]FASTAAdd to Basket

    « Hide

    VDFNVPLKDG QVKDPTRIQG SIPSIKKILE QNPKGLVLMS HLGRPDGNRV    50
    EKHSMKPVVP KLEQLLGTKV KFLNDCVGKD VEEAVKSSRN GEIILLENLR 100
    FHAEEEGKSI DAAGNKVKAD PKAVKEFRKS LTSLGDLYVN DAFGTAHRAH 150
    SSMVGVDHKI RAAGYLLKKE LDYFSKALES PNRPFLVVLG GAKVKDKIQL 200
    IESMIDKVDE MIIGGGMAFT FLKRIHNMEI GNSLFDEEGY KIVDQLLEKA 250
    KAKGVKIHLP VDFLCGDSLE ANANTQIHDL ISGIPKGWIG LDAGPKTIAL 300
    NADAVARANT IVWNGPQGRF EVDKFRQGSA DLLKRVSART AAGATSIIGG 350
    GDTVNLVQQE KATDKVSHVS TGGGE 375
    Length:375
    Mass (Da):40,673
    Last modified:July 1, 1997 - v1
    Checksum:i141D0ED9620C34DB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-terminal residuei375 – 3751

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF001851 Genomic DNA. Translation: AAB58243.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF001851 Genomic DNA. Translation: AAB58243.1 .

    3D structure databases

    ProteinModelPortali O00871.
    SMRi O00871. Positions 1-374.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O00871.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Pearlman R.E.
      Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiPGK_TETPY
    AccessioniPrimary (citable) accession number: O00871
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: July 1, 1997
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3