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O00871

- PGK_TETPY

UniProt

O00871 - PGK_TETPY

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Protein
Phosphoglycerate kinase
Gene
PGK
Organism
Tetrahymena pyriformis
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei17 – 171Substrate By similarity
Binding sitei100 – 1001Substrate By similarity
Binding sitei148 – 1481Substrate By similarity
Binding sitei197 – 1971ATP By similarity
Binding sitei290 – 2901ATP; via carbonyl oxygen By similarity
Binding sitei321 – 3211ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi350 – 3534ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGK
OrganismiTetrahymena pyriformis
Taxonomic identifieri5908 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›375›375Phosphoglycerate kinase
PRO_0000145860Add
BLAST

Proteomic databases

PRIDEiO00871.

Interactioni

Subunit structurei

Monomer By similarity.

Structurei

3D structure databases

ProteinModelPortaliO00871.
SMRiO00871. Positions 1-374.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2 – 43Substrate binding By similarity
Regioni41 – 444Substrate binding By similarity

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Fragment.

O00871-1 [UniParc]FASTAAdd to Basket

« Hide

VDFNVPLKDG QVKDPTRIQG SIPSIKKILE QNPKGLVLMS HLGRPDGNRV    50
EKHSMKPVVP KLEQLLGTKV KFLNDCVGKD VEEAVKSSRN GEIILLENLR 100
FHAEEEGKSI DAAGNKVKAD PKAVKEFRKS LTSLGDLYVN DAFGTAHRAH 150
SSMVGVDHKI RAAGYLLKKE LDYFSKALES PNRPFLVVLG GAKVKDKIQL 200
IESMIDKVDE MIIGGGMAFT FLKRIHNMEI GNSLFDEEGY KIVDQLLEKA 250
KAKGVKIHLP VDFLCGDSLE ANANTQIHDL ISGIPKGWIG LDAGPKTIAL 300
NADAVARANT IVWNGPQGRF EVDKFRQGSA DLLKRVSART AAGATSIIGG 350
GDTVNLVQQE KATDKVSHVS TGGGE 375
Length:375
Mass (Da):40,673
Last modified:July 1, 1997 - v1
Checksum:i141D0ED9620C34DB
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei375 – 3751

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF001851 Genomic DNA. Translation: AAB58243.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF001851 Genomic DNA. Translation: AAB58243.1 .

3D structure databases

ProteinModelPortali O00871.
SMRi O00871. Positions 1-374.
ModBasei Search...

Proteomic databases

PRIDEi O00871.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Pearlman R.E.
    Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPGK_TETPY
AccessioniPrimary (citable) accession number: O00871
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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