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O00869

- PGK_PARPR

UniProt

O00869 - PGK_PARPR

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Protein

Phosphoglycerate kinase

Gene

PGK

Organism
Paramecium primaurelia
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei17 – 171SubstrateBy similarity
Binding sitei99 – 991SubstrateBy similarity
Binding sitei147 – 1471SubstrateBy similarity
Binding sitei196 – 1961ATPBy similarity
Binding sitei289 – 2891ATP; via carbonyl oxygenBy similarity
Binding sitei320 – 3201ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi349 – 3524ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGK
OrganismiParamecium primaurelia
Taxonomic identifieri5886 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›367›367Phosphoglycerate kinasePRO_0000145858Add
BLAST

Proteomic databases

PRIDEiO00869.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO00869.
SMRiO00869. Positions 1-367.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2 – 43Substrate bindingBy similarity
Regioni41 – 444Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Fragment.

O00869-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
VDFNVPIKEG KVKNTTRIQG AIPTLKKILE QNPKNVTLMS HMGRPDGKRV
60 70 80 90 100
EKDSLKIVVP KLEELLGTKV NFVNDCVGSE ALEASNAGNG QINLLENLRF
110 120 130 140 150
HIQEEGKGLD ANGAKIKADK ESVKKFRKEL SSLGDIYVND AFGTAHRAHS
160 170 180 190 200
SMVGIDHKIR VAGYLMKKEL DYFAKALETP QRPFLVILGG AKVADKIQLI
210 220 230 240 250
KSMLDKVDEM IIGGGMAFTF LKKYIMFPIG KSLFDEEGYK IVDEIIAKAK
260 270 280 290 300
EKNVKIHLPT DFVCGTGLDA SSPVALHDLK SGIPDGWLGL DAGQLTQREN
310 320 330 340 350
ADAIGRAKTI VWNGPQGAFE IEQFKNGSVS MLNALVKQTQ NGATTIVGGG
360
DTVNLVGANK ANDKLSH
Length:367
Mass (Da):39,876
Last modified:July 1, 1997 - v1
Checksum:iDEF64500127DE460
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei367 – 3671

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001849 Genomic DNA. Translation: AAB58241.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF001849 Genomic DNA. Translation: AAB58241.1 .

3D structure databases

ProteinModelPortali O00869.
SMRi O00869. Positions 1-367.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi O00869.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Pearlman R.E.
    Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPGK_PARPR
AccessioniPrimary (citable) accession number: O00869
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: October 1, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3