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O00869 (PGK_PARPR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK
OrganismParamecium primaurelia
Taxonomic identifier5886 [NCBI]
Taxonomic lineageEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium

Protein attributes

Sequence length367 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›367›367Phosphoglycerate kinase
PRO_0000145858

Regions

Nucleotide binding349 – 3524ATP By similarity
Region2 – 43Substrate binding By similarity
Region41 – 444Substrate binding By similarity

Sites

Binding site171Substrate By similarity
Binding site991Substrate By similarity
Binding site1471Substrate By similarity
Binding site1961ATP By similarity
Binding site2891ATP; via carbonyl oxygen By similarity
Binding site3201ATP By similarity

Experimental info

Non-terminal residue11
Non-terminal residue3671

Sequences

Sequence LengthMass (Da)Tools
O00869 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: DEF64500127DE460

FASTA36739,876
        10         20         30         40         50         60 
VDFNVPIKEG KVKNTTRIQG AIPTLKKILE QNPKNVTLMS HMGRPDGKRV EKDSLKIVVP 

        70         80         90        100        110        120 
KLEELLGTKV NFVNDCVGSE ALEASNAGNG QINLLENLRF HIQEEGKGLD ANGAKIKADK 

       130        140        150        160        170        180 
ESVKKFRKEL SSLGDIYVND AFGTAHRAHS SMVGIDHKIR VAGYLMKKEL DYFAKALETP 

       190        200        210        220        230        240 
QRPFLVILGG AKVADKIQLI KSMLDKVDEM IIGGGMAFTF LKKYIMFPIG KSLFDEEGYK 

       250        260        270        280        290        300 
IVDEIIAKAK EKNVKIHLPT DFVCGTGLDA SSPVALHDLK SGIPDGWLGL DAGQLTQREN 

       310        320        330        340        350        360 
ADAIGRAKTI VWNGPQGAFE IEQFKNGSVS MLNALVKQTQ NGATTIVGGG DTVNLVGANK 


ANDKLSH 

« Hide

References

[1]Pearlman R.E.
Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF001849 Genomic DNA. Translation: AAB58241.1.

3D structure databases

ProteinModelPortalO00869.
SMRO00869. Positions 1-367.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO00869.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_PARPR
AccessionPrimary (citable) accession number: O00869
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways