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O00852 (PGK_GLACH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:PGK
OrganismGlaucoma chattoni
Taxonomic identifier5883 [NCBI]
Taxonomic lineageEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaGlaucomidaeGlaucoma

Protein attributes

Sequence length376 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.

Subunit structure

Monomer By similarity.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›376›376Phosphoglycerate kinase
PRO_0000145852

Regions

Nucleotide binding350 – 3534ATP By similarity
Region2 – 43Substrate binding By similarity
Region41 – 444Substrate binding By similarity

Sites

Binding site171Substrate By similarity
Binding site1001Substrate By similarity
Binding site1481Substrate By similarity
Binding site1971ATP By similarity
Binding site2901ATP; via carbonyl oxygen By similarity
Binding site3211ATP By similarity

Experimental info

Non-terminal residue11
Non-terminal residue3761

Sequences

Sequence LengthMass (Da)Tools
O00852 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: A25D27DC6173DDA9

FASTA37640,873
        10         20         30         40         50         60 
VDFNVPLKEG VVKDPTRIAG SIPSIKKILE TNPRGLVLMS HLGRPDGQRV EKHSLKPVLP 

        70         80         90        100        110        120 
KLEELLGTKV TFLNDCVGKD VEEAVKSSRN GEIILLENLR FHIEEEGKAV DAAGNKVKAD 

       130        140        150        160        170        180 
PKAVKEFRKS LTNLGDLFFN DAFGTAHRAH SSMVGVDHKI RVAGYLLKKE LEYFSKALES 

       190        200        210        220        230        240 
PTLPFCVVLG GAKVKDKIQL INSMLDNVNE MIIGGGMAFT FLKRLHNLEI GNSLFDEEGY 

       250        260        270        280        290        300 
KIVDELLEKA KKKNVKIHLP VDFLCGDSLE ANANTAIHDL QSGIPKGWIG LDAGPKTIAL 

       310        320        330        340        350        360 
NAEVIARANT IVWNGPQGRF EVDKFRNGSS DLLKKVIERT KTGATSIIGG GDTVNLVQQE 

       370 
KASNKVSHVS TGGGAS 

« Hide

References

[1]Pearlman R.E.
Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF001850 Genomic DNA. Translation: AAB58242.1.

3D structure databases

ProteinModelPortalO00852.
SMRO00852. Positions 1-376.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_GLACH
AccessionPrimary (citable) accession number: O00852
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: July 1, 1997
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways