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Protein
Submitted name:

Micronemal protein MIC2

Gene
N/A
Organism
Toxoplasma gondii
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Micronemal protein MIC2Imported
OrganismiToxoplasma gondiiImported
Taxonomic identifieri5811 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi71 ↔ 264Combined sources
Disulfide bondi78 ↔ 164Combined sources
Disulfide bondi273 ↔ 319Combined sources
Glycosylationi276 – 2761C-linked (Man)Combined sourcesCAR_5005389129
Disulfide bondi282 ↔ 331Combined sources
Disulfide bondi308 ↔ 311Combined sources

Interactioni

Protein-protein interaction databases

STRINGi5811.TGME49_001780.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4OKRX-ray2.60A/B67-337[»]
4OKUX-ray3.20A/B30-337[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3544. Eukaryota.
KOG4475. Eukaryota.
ENOG410XNMM. LUCA.
ENOG410ZN3C. LUCA.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR000884. TSP1_rpt.
IPR002035. VWF_A.
[Graphical view]
PfamiPF00090. TSP_1. 6 hits.
PF00092. VWA. 1 hit.
[Graphical view]
SMARTiSM00209. TSP1. 6 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF82895. SSF82895. 5 hits.
PROSITEiPS50092. TSP1. 3 hits.
PS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O00816-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLQREAVFG LMFACGMWMW PSEVAGGGWS IVDALRKRYD TSRGGDANGV
60 70 80 90 100
DTSGVEDVIQ SDSAIGAAEG CTNQLDICFL IDSSGSIGIQ NFRLVKQFLH
110 120 130 140 150
TFLMVLPIGP EEVNNAVVTY STDVHLQWDL QSPNAVDKQL AAHAVLEMPY
160 170 180 190 200
KKGSTNTSDG LKACKQILFT GSRPGREHVP KLVIGMTDGE SDSDFRTVRA
210 220 230 240 250
AKEIRELGGI VTVLAVGHYV KHSECRSMCG CSGTSDDDSP CPLYLRADWG
260 270 280 290 300
QLATAIKPML KEVCKTLPQD AICSDWSAWS PCSVSCGDGS QIRTRTEVSA
310 320 330 340 350
PQPGTPTCPD CPAPMGRTCV EQGGLEEIRE CSAGVCAVDA GCGVWGEWSA
360 370 380 390 400
WSASCGNATR KRERTRYNDP PPQGAGRRCE NQDPPVLQEQ TEEATLAPCI
410 420 430 440 450
TIPPTPPEWA AWSDCTVTCG GGNRHRVRNA LPPGLGSQNG ESDESLVSKL
460 470 480 490 500
WPGTDLRQEE ACNTSPCPIN ATCGQFEEWS TCSVSCGGGL KTRSRNPWNE
510 520 530 540 550
DQQHGGLSCE QQHPGGRTET VTCNPQACPV DERPGEWAEW GECSVTCGDG
560 570 580 590 600
VRERRRGKSL VEAKFGGRTI DQQNEALPED LKIKNVEYEP CSYPACGASC
610 620 630 640 650
TYVWSDWNKC VCPMGYQARH AAVKFDYRNK PCDLPTFETK ACSCGETNPV
660 670 680 690 700
PSEGTTPGAP GATGPEQPNQ RPLPEGSDEN ETPTNEEGEQ SKKESGSGIA
710 720 730 740 750
GAIAGGVIGG LILLGAAGGA SYHYYLSSSV GSPSAEIEYE ADDGATKVVM
760
EEEKETLVPV DDDSDMWME
Length:769
Mass (Da):82,620
Last modified:July 1, 1997 - v1
Checksum:iDC85EE8D7689A407
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62660 Genomic DNA. Translation: AAB63303.1.

Genome annotation databases

EnsemblProtistsiEPR61724; EPR61724; TGGT1_201780.
ESS33044; ESS33044; TGVEG_201780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62660 Genomic DNA. Translation: AAB63303.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4OKRX-ray2.60A/B67-337[»]
4OKUX-ray3.20A/B30-337[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5811.TGME49_001780.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEPR61724; EPR61724; TGGT1_201780.
ESS33044; ESS33044; TGVEG_201780.

Phylogenomic databases

eggNOGiKOG3544. Eukaryota.
KOG4475. Eukaryota.
ENOG410XNMM. LUCA.
ENOG410ZN3C. LUCA.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR000884. TSP1_rpt.
IPR002035. VWF_A.
[Graphical view]
PfamiPF00090. TSP_1. 6 hits.
PF00092. VWA. 1 hit.
[Graphical view]
SMARTiSM00209. TSP1. 6 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF82895. SSF82895. 5 hits.
PROSITEiPS50092. TSP1. 3 hits.
PS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Haag F.A.
    Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RHImported.
  2. "Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2."
    Wan K.L., Carruthers V.B., Sibley L.D., Ajioka J.W.
    Mol. Biochem. Parasitol. 84:203-214(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RHImported.
  3. "Structures of the Toxoplasma gliding motility adhesin."
    Song G., Springer T.A.
    Proc. Natl. Acad. Sci. U.S.A. 111:4862-4867(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 67-337, GLYCOSYLATION AT TRP-276, DISULFIDE BONDS.

Entry informationi

Entry nameiO00816_TOXGO
AccessioniPrimary (citable) accession number: O00816
Secondary accession number(s): B9PUS9, S7W437
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.