##gff-version 3
O00755	UniProtKB	Signal peptide	1	31	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00755	UniProtKB	Chain	32	349	.	.	.	ID=PRO_0000041442;Note=Protein Wnt-7a	
O00755	UniProtKB	Region	238	266	.	.	.	Note=Disordered linker;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Lipidation	206	206	.	.	.	Note=O-palmitoleoyl serine%3B by PORCN;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Glycosylation	83	83	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00755	UniProtKB	Glycosylation	127	127	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00755	UniProtKB	Glycosylation	295	295	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00755	UniProtKB	Disulfide bond	73	84	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	123	131	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	133	152	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	200	214	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	202	209	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	278	309	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	294	304	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	308	348	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	324	339	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	326	336	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Disulfide bond	331	332	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P28026	
O00755	UniProtKB	Natural variant	72	72	.	.	.	ID=VAR_065765;Note=In LPHAS. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21271649;Dbxref=dbSNP:rs397514666,PMID:21271649	
O00755	UniProtKB	Natural variant	102	102	.	.	.	ID=VAR_077340;Note=In LPHAS%3B uncertain significance. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27638328;Dbxref=dbSNP:rs879255548,PMID:27638328	
O00755	UniProtKB	Natural variant	109	109	.	.	.	ID=VAR_030673;Note=In FUHRS%3B retains activity that is significant but not comparable to wild-type activity. A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16826533;Dbxref=dbSNP:rs104893832,PMID:16826533	
O00755	UniProtKB	Natural variant	222	222	.	.	.	ID=VAR_064480;Note=In LPHAS. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20949531;Dbxref=dbSNP:rs397514643,PMID:20949531	
O00755	UniProtKB	Natural variant	292	292	.	.	.	ID=VAR_030674;Note=In LPHAS%3B results in a loss of function mutation with some residual activity. R->C;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16826533,ECO:0000269|PubMed:17431918;Dbxref=dbSNP:rs104893835,PMID:16826533,PMID:17431918	
O00755	UniProtKB	Mutagenesis	206	206	.	.	.	Note=Does not affect interaction with RECK. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Mutagenesis	241	241	.	.	.	Note=In 4A%3B abolished interaction with RECK%3B when associated with 251-A-A-252 and A-262. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Mutagenesis	251	252	.	.	.	Note=In 4A%3B abolished interaction with RECK%3B when associated with A-241 and A-262. FL->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Mutagenesis	262	262	.	.	.	Note=In 4A%3B abolished interaction with RECK%3B when associated with A-241 and 251-A-A-252. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30026314;Dbxref=PMID:30026314	
O00755	UniProtKB	Sequence conflict	6	6	.	.	.	Note=R->L;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	14	14	.	.	.	Note=L->F;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	20	20	.	.	.	Note=Y->C;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	35	35	.	.	.	Note=S->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	103	104	.	.	.	Note=EA->DG;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	125	125	.	.	.	Note=Q->H;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	280	280	.	.	.	Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	329	329	.	.	.	Note=H->Q;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00755	UniProtKB	Sequence conflict	338	338	.	.	.	Note=T->K;Ontology_term=ECO:0000305;evidence=ECO:0000305