##gff-version 3
O00748	UniProtKB	Signal peptide	1	26	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9169443;Dbxref=PMID:9169443	
O00748	UniProtKB	Chain	27	559	.	.	.	ID=PRO_0000008572;Note=Cocaine esterase	
O00748	UniProtKB	Motif	556	559	.	.	.	Note=Prevents secretion from ER;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00748	UniProtKB	Active site	228	228	.	.	.	Note=Acyl-ester intermediate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10039	
O00748	UniProtKB	Active site	345	345	.	.	.	Note=Charge relay system;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P23141	
O00748	UniProtKB	Active site	457	457	.	.	.	Note=Charge relay system;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P23141	
O00748	UniProtKB	Modified residue	27	27	.	.	.	Note=Pyrrolidone carboxylic acid;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P14943	
O00748	UniProtKB	Glycosylation	111	111	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218	
O00748	UniProtKB	Glycosylation	276	276	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
O00748	UniProtKB	Disulfide bond	95	123	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P23141	
O00748	UniProtKB	Disulfide bond	280	291	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P23141	
O00748	UniProtKB	Alternative sequence	1	1	.	.	.	ID=VSP_059804;Note=In isoform 3 and isoform 4. M->MTAQSRSPTTPTFPGPSQRTPLTPCPVQTPRLGKALIHCWTDPGQPLGEQQRVRRQRTETSEPTM;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:28677105;Dbxref=PMID:28677105	
O00748	UniProtKB	Alternative sequence	458	474	.	.	.	ID=VSP_010161;Note=In isoform 2 and isoform 4. GDELPFVFRSFFGGNYI->V;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005	
O00748	UniProtKB	Natural variant	34	34	.	.	.	ID=VAR_018396;Note=R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15618752;Dbxref=dbSNP:rs72547531,PMID:15618752	
O00748	UniProtKB	Natural variant	206	206	.	.	.	ID=VAR_018397;Note=R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12721789;Dbxref=dbSNP:rs8192924,PMID:12721789	
O00748	UniProtKB	Sequence conflict	2	10	.	.	.	Note=Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00748	UniProtKB	Sequence conflict	180	180	.	.	.	Note=G->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00748	UniProtKB	Sequence conflict	239	239	.	.	.	Note=V->M;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00748	UniProtKB	Sequence conflict	385	385	.	.	.	Note=F->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O00748	UniProtKB	Sequence conflict	519	519	.	.	.	Note=Q->R;Ontology_term=ECO:0000305;evidence=ECO:0000305