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O00481 (BT3A1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 126. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (7) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Butyrophilin subfamily 3 member A1
Alternative name(s):
CD_antigen=CD277
Gene names
Name:BTN3A1
Synonyms:BTF5
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. Ref.9 Ref.10 Ref.11 Ref.12

Subunit structure

Homodimer. Ref.12

Subcellular location

Cell membrane; Single-pass type I membrane protein Ref.9 Ref.10 Ref.11.

Tissue specificity

Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle. Ref.2 Ref.8 Ref.9 Ref.10

Post-translational modification

N-glycosylated. Ref.8 Ref.12

Sequence similarities

Belongs to the immunoglobulin superfamily. BTN/MOG family.

Contains 1 B30.2/SPRY domain.

Contains 2 Ig-like V-type (immunoglobulin-like) domains.

Sequence caution

The sequence CAA69164.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

TFF1P041553EBI-2809309,EBI-743871

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: O00481-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: O00481-2)

The sequence of this isoform differs from the canonical sequence as follows:
     340-352: ADVILDPKTANPI → GEEMLQMRLHFVK
     353-513: Missing.
Note: No experimental confirmation available.
Isoform 3 (identifier: O00481-3)

The sequence of this isoform differs from the canonical sequence as follows:
     340-513: ADVILDPKTA...EPTALTICPA → GPPIGQTQQQ...SWGPEEGGES
Note: No experimental confirmation available.
Isoform 4 (identifier: O00481-4)

The sequence of this isoform differs from the canonical sequence as follows:
     143-194: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2929 Potential
Chain30 – 513484Butyrophilin subfamily 3 member A1
PRO_0000014532

Regions

Topological domain30 – 254225Extracellular Potential
Transmembrane255 – 27117Helical; Potential
Topological domain272 – 513242Cytoplasmic Potential
Domain30 – 139110Ig-like V-type 1
Domain145 – 23692Ig-like V-type 2
Domain322 – 513192B30.2/SPRY

Amino acid modifications

Glycosylation1151N-linked (GlcNAc...) Ref.12
Disulfide bond52 ↔ 126 Ref.12
Disulfide bond166 ↔ 220 Ref.12

Natural variations

Alternative sequence143 – 19452Missing in isoform 4.
VSP_045062
Alternative sequence340 – 513174ADVIL…TICPA → GPPIGQTQQQTRGQGSPVAL SQESAQRTDSWGPEEGGES in isoform 3.
VSP_042034
Alternative sequence340 – 35213ADVIL…TANPI → GEEMLQMRLHFVK in isoform 2.
VSP_012714
Alternative sequence353 – 513161Missing in isoform 2.
VSP_012715
Natural variant151R → H. Ref.3
Corresponds to variant rs56161420 [ dbSNP | Ensembl ].
VAR_061305
Natural variant2241S → N. Ref.1
Corresponds to variant rs1057933 [ dbSNP | Ensembl ].
VAR_021170
Natural variant2821R → T. Ref.3
Corresponds to variant rs41266839 [ dbSNP | Ensembl ].
VAR_061306
Natural variant4561P → T. Ref.7
Corresponds to variant rs4712990 [ dbSNP | Ensembl ].
VAR_028788

Experimental info

Sequence conflict131N → S in BAG58563. Ref.3
Sequence conflict251M → T in BAD97194. Ref.4
Sequence conflict461E → K in BAG61334. Ref.3
Sequence conflict1111L → F in CAA69164. Ref.1
Sequence conflict1181A → G in CAA69164. Ref.1
Sequence conflict121 – 1222SG → RW in CAA69164. Ref.1
Sequence conflict1301D → G in BAG58563. Ref.3
Sequence conflict2391D → R in CAA69164. Ref.1
Sequence conflict2541G → R in AAB53430. Ref.2
Sequence conflict5091T → S in AAB53430. Ref.2

Secondary structure

......................................... 513
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified October 31, 2006. Version 3.
Checksum: 8D834D70526D1F6F

FASTA51357,677
        10         20         30         40         50         60 
MKMASFLAFL LLNFRVCLLL LQLLMPHSAQ FSVLGPSGPI LAMVGEDADL PCHLFPTMSA 

        70         80         90        100        110        120 
ETMELKWVSS SLRQVVNVYA DGKEVEDRQS APYRGRTSIL RDGITAGKAA LRIHNVTASD 

       130        140        150        160        170        180 
SGKYLCYFQD GDFYEKALVE LKVAALGSDL HVDVKGYKDG GIHLECRSTG WYPQPQIQWS 

       190        200        210        220        230        240 
NNKGENIPTV EAPVVADGVG LYAVAASVIM RGSSGEGVSC TIRSSLLGLE KTASISIADP 

       250        260        270        280        290        300 
FFRSAQRWIA ALAGTLPVLL LLLGGAGYFL WQQQEEKKTQ FRKKKREQEL REMAWSTMKQ 

       310        320        330        340        350        360 
EQSTRVKLLE ELRWRSIQYA SRGERHSAYN EWKKALFKPA DVILDPKTAN PILLVSEDQR 

       370        380        390        400        410        420 
SVQRAKEPQD LPDNPERFNW HYCVLGCESF ISGRHYWEVE VGDRKEWHIG VCSKNVQRKG 

       430        440        450        460        470        480 
WVKMTPENGF WTMGLTDGNK YRTLTEPRTN LKLPKPPKKV GVFLDYETGD ISFYNAVDGS 

       490        500        510 
HIHTFLDVSF SEALYPVFRI LTLEPTALTI CPA 

« Hide

Isoform 2 [UniParc].

Checksum: 274CA3723C653772
Show »

FASTA35239,397
Isoform 3 [UniParc].

Checksum: 274B31308FA9B73D
Show »

FASTA37841,819
Isoform 4 [UniParc].

Checksum: 72FE04DA9664783D
Show »

FASTA46152,019

References

« Hide 'large scale' references
[1]"Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex."
Tazi-Ahnini R., Henry J., Offer C., Bouissou-Bouchouata C., Mather I.H., Pontarotti P.
Immunogenetics 47:55-63(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANT ASN-224.
[2]"A 1.1-Mb transcript map of the hereditary hemochromatosis locus."
Ruddy D.A., Kronmal G.S., Lee V.K., Mintier G.A., Quintana L., Domingo R. Jr., Meyer N.C., Irrinki A., McClelland E.E., Fullan A., Mapa F.A., Moore T., Thomas W., Loeb D.B., Harmon C., Tsuchihashi Z., Wolff R.K., Schatzman R.C., Feder J.N.
Genome Res. 7:441-456(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
[3]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4), VARIANTS HIS-15 AND THR-282.
Tissue: Hippocampus and Thalamus.
[4]Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Tissue: Synovium.
[5]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT THR-456.
[8]"Stimulation of human butyrophilin 3 molecules results in negative regulation of cellular immunity."
Yamashiro H., Yoshizaki S., Tadaki T., Egawa K., Seo N.
J. Leukoc. Biol. 88:757-767(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: GLYCOSYLATION, TISSUE SPECIFICITY.
[9]"CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells."
Cubillos-Ruiz J.R., Martinez D., Scarlett U.K., Rutkowski M.R., Nesbeth Y.C., Camposeco-Jacobs A.L., Conejo-Garcia J.R.
Oncotarget 1:329-338(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[10]"Differential role for CD277 as a co-regulator of the immune signal in T and NK cells."
Messal N., Mamessier E., Sylvain A., Celis-Gutierrez J., Thibult M.L., Chetaille B., Firaguay G., Pastor S., Guillaume Y., Wang Q., Hirsch I., Nunes J.A., Olive D.
Eur. J. Immunol. 41:3443-3454(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[11]"Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human gammadelta T-cell subset."
Harly C., Guillaume Y., Nedellec S., Peigne C.M., Monkkonen H., Monkkonen J., Li J., Kuball J., Adams E.J., Netzer S., Dechanet-Merville J., Leger A., Herrmann T., Breathnach R., Olive D., Bonneville M., Scotet E.
Blood 120:2269-2279(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.
[12]"The molecular basis for modulation of human Vgamma9Vdelta2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies."
Palakodeti A., Sandstrom A., Sundaresan L., Harly C., Nedellec S., Olive D., Scotet E., Bonneville M., Adams E.J.
J. Biol. Chem. 287:32780-32790(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.94 ANGSTROMS) OF 30-246, FUNCTION, SUBUNIT, DISULFIDE BONDS, GLYCOSYLATION AT ASN-115.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y07827 mRNA. Translation: CAA69164.1. Different initiation.
U90552 mRNA. Translation: AAB53430.1.
AK223474 mRNA. Translation: BAD97194.1.
AK290193 mRNA. Translation: BAF82882.1.
AK295720 mRNA. Translation: BAG58563.1.
AK299327 mRNA. Translation: BAG61334.1.
AL021917 Genomic DNA. Translation: CAC03424.3.
AL021917 Genomic DNA. Translation: CAM28245.1.
CH471087 Genomic DNA. Translation: EAW55566.1.
CH471087 Genomic DNA. Translation: EAW55567.1.
BC118586 mRNA. Translation: AAI18587.1.
BC121800 mRNA. Translation: AAI21801.1.
RefSeqNP_001138480.1. NM_001145008.1.
NP_001138481.1. NM_001145009.1.
NP_008979.3. NM_007048.5.
NP_919423.1. NM_194441.2.
XP_005248891.1. XM_005248834.2.
UniGeneHs.191510.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4F80X-ray1.94A30-246[»]
4F9LX-ray3.14A/B30-246[»]
4F9PX-ray3.52A/B30-246[»]
4JKWX-ray2.01A28-143[»]
4K55X-ray1.91A28-143[»]
ProteinModelPortalO00481.
SMRO00481. Positions 30-243, 342-498.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid116294. 2 interactions.
IntActO00481. 2 interactions.
STRING9606.ENSP00000289361.

PTM databases

PhosphoSiteO00481.

Proteomic databases

PaxDbO00481.
PRIDEO00481.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000289361; ENSP00000289361; ENSG00000026950. [O00481-1]
ENST00000414912; ENSP00000406667; ENSG00000026950. [O00481-4]
ENST00000425234; ENSP00000396684; ENSG00000026950. [O00481-3]
ENST00000476549; ENSP00000420010; ENSG00000026950. [O00481-2]
GeneID11119.
KEGGhsa:11119.
UCSCuc003nhv.3. human. [O00481-1]
uc010jqj.3. human. [O00481-2]
uc011dkj.2. human. [O00481-3]

Organism-specific databases

CTD11119.
GeneCardsGC06P026402.
HGNCHGNC:1138. BTN3A1.
HPAHPA012565.
MIM613593. gene.
neXtProtNX_O00481.
PharmGKBPA25459.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG326834.
HOGENOMHOG000230860.
HOVERGENHBG050747.
InParanoidO00481.
KOK06712.
OMANVQRKGW.
OrthoDBEOG73804F.
PhylomeDBO00481.
TreeFamTF331083.

Gene expression databases

ArrayExpressO00481.
BgeeO00481.
CleanExHS_BTN3A1.
GenevestigatorO00481.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
InterProIPR001870. B30.2/SPRY.
IPR003879. Butyrophylin.
IPR013162. CD80_C2-set.
IPR008985. ConA-like_lec_gl_sf.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
IPR006574. PRY.
IPR018355. SPla/RYanodine_receptor_subgr.
IPR003877. SPRY_rcpt.
[Graphical view]
PfamPF08205. C2-set_2. 1 hit.
PF13765. PRY. 1 hit.
PF00622. SPRY. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSPR01407. BUTYPHLNCDUF.
SMARTSM00409. IG. 1 hit.
SM00589. PRY. 1 hit.
SM00449. SPRY. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
PROSITEPS50188. B302_SPRY. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

GeneWikiButyrophilin,_subfamily_3,_member_A1.
GenomeRNAi11119.
NextBio42260.
PROO00481.
SOURCESearch...

Entry information

Entry nameBT3A1_HUMAN
AccessionPrimary (citable) accession number: O00481
Secondary accession number(s): A2A278 expand/collapse secondary AC list , A8K2C8, B4DIQ1, B4DRM2, E9PGB4, E9PHG8, Q0P515, Q147X5, Q53F15, Q99420, Q9HCY1
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: October 31, 2006
Last modified: April 16, 2014
This is version 126 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 6

Human chromosome 6: entries, gene names and cross-references to MIM

Human cell differentiation molecules

CD nomenclature of surface proteins of human leucocytes and list of entries