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O00339

- MATN2_HUMAN

UniProt

O00339 - MATN2_HUMAN

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Protein

Matrilin-2

Gene

MATN2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Involved in matrix assembly.By similarity

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Matrilin-2
Gene namesi
Name:MATN2
ORF Names:UNQ193/PRO219
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 8

Organism-specific databases

HGNCiHGNC:6908. MATN2.

Subcellular locationi

GO - Cellular componenti

  1. proteinaceous extracellular matrix Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30651.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 956933Matrilin-2PRO_0000007655Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi221 – 2211N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi242 ↔ 253PROSITE-ProRule annotation
Disulfide bondi249 ↔ 262PROSITE-ProRule annotation
Disulfide bondi264 ↔ 277PROSITE-ProRule annotation
Disulfide bondi283 ↔ 294PROSITE-ProRule annotation
Disulfide bondi290 ↔ 303PROSITE-ProRule annotation
Disulfide bondi305 ↔ 318PROSITE-ProRule annotation
Disulfide bondi324 ↔ 335PROSITE-ProRule annotation
Disulfide bondi331 ↔ 344PROSITE-ProRule annotation
Disulfide bondi346 ↔ 359PROSITE-ProRule annotation
Disulfide bondi365 ↔ 376PROSITE-ProRule annotation
Disulfide bondi372 ↔ 385PROSITE-ProRule annotation
Disulfide bondi387 ↔ 400PROSITE-ProRule annotation
Disulfide bondi406 ↔ 417PROSITE-ProRule annotation
Disulfide bondi413 ↔ 426PROSITE-ProRule annotation
Disulfide bondi428 ↔ 441PROSITE-ProRule annotation
Disulfide bondi447 ↔ 458PROSITE-ProRule annotation
Disulfide bondi454 ↔ 467PROSITE-ProRule annotation
Disulfide bondi469 ↔ 482PROSITE-ProRule annotation
Disulfide bondi488 ↔ 499PROSITE-ProRule annotation
Disulfide bondi495 ↔ 508PROSITE-ProRule annotation
Disulfide bondi510 ↔ 523PROSITE-ProRule annotation
Disulfide bondi529 ↔ 540PROSITE-ProRule annotation
Disulfide bondi536 ↔ 549PROSITE-ProRule annotation
Disulfide bondi551 ↔ 564PROSITE-ProRule annotation
Disulfide bondi570 ↔ 581PROSITE-ProRule annotation
Disulfide bondi577 ↔ 590PROSITE-ProRule annotation
Disulfide bondi592 ↔ 605PROSITE-ProRule annotation
Disulfide bondi611 ↔ 622PROSITE-ProRule annotation
Disulfide bondi618 ↔ 631PROSITE-ProRule annotation
Disulfide bondi633 ↔ 646PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiO00339.
PaxDbiO00339.
PRIDEiO00339.

PTM databases

PhosphoSiteiO00339.

Expressioni

Gene expression databases

BgeeiO00339.
CleanExiHS_MATN2.
ExpressionAtlasiO00339. baseline and differential.
GenevestigatoriO00339.

Organism-specific databases

HPAiCAB033879.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ATXN7O152652EBI-949020,EBI-708350
CACNA1AO005552EBI-949020,EBI-766279

Protein-protein interaction databases

BioGridi110317. 12 interactions.
DIPiDIP-47267N.
IntActiO00339. 6 interactions.
STRINGi9606.ENSP00000254898.

Structurei

3D structure databases

ProteinModelPortaliO00339.
SMRiO00339. Positions 57-647, 649-871.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 232176VWFA 1PROSITE-ProRule annotationAdd
BLAST
Domaini238 – 27841EGF-like 1PROSITE-ProRule annotationAdd
BLAST
Domaini279 – 31941EGF-like 2PROSITE-ProRule annotationAdd
BLAST
Domaini320 – 36041EGF-like 3PROSITE-ProRule annotationAdd
BLAST
Domaini361 – 40141EGF-like 4PROSITE-ProRule annotationAdd
BLAST
Domaini402 – 44241EGF-like 5PROSITE-ProRule annotationAdd
BLAST
Domaini443 – 48341EGF-like 6PROSITE-ProRule annotationAdd
BLAST
Domaini484 – 52441EGF-like 7PROSITE-ProRule annotationAdd
BLAST
Domaini525 – 56541EGF-like 8PROSITE-ProRule annotationAdd
BLAST
Domaini566 – 60641EGF-like 9PROSITE-ProRule annotationAdd
BLAST
Domaini607 – 64741EGF-like 10PROSITE-ProRule annotationAdd
BLAST
Domaini655 – 830176VWFA 2PROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili917 – 95539Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 10 EGF-like domains.PROSITE-ProRule annotation
Contains 2 VWFA domains.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGiNOG297993.
GeneTreeiENSGT00760000119000.
HOVERGENiHBG056906.
InParanoidiO00339.
OrthoDBiEOG70GMF3.
TreeFamiTF330078.

Family and domain databases

Gene3Di1.20.5.30. 1 hit.
3.40.50.410. 2 hits.
InterProiIPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR009030. Growth_fac_rcpt_N_dom.
IPR019466. Matrilin_coiled-coil_trimer.
IPR002035. VWF_A.
[Graphical view]
PfamiPF12662. cEGF. 1 hit.
PF07645. EGF_CA. 1 hit.
PF10393. Matrilin_ccoil. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view]
SMARTiSM00181. EGF. 9 hits.
SM00179. EGF_CA. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 2 hits.
SSF57184. SSF57184. 3 hits.
PROSITEiPS00010. ASX_HYDROXYL. 9 hits.
PS01186. EGF_2. 9 hits.
PS50026. EGF_3. 4 hits.
PS50234. VWFA. 2 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O00339-1) [UniParc]FASTAAdd to Basket

Also known as: Long

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEKMLAGCFL LILGQIVLLP AEARERSRGR SISRGRHART HPQTALLESS
60 70 80 90 100
CENKRADLVF IIDSSRSVNT HDYAKVKEFI VDILQFLDIG PDVTRVGLLQ
110 120 130 140 150
YGSTVKNEFS LKTFKRKSEV ERAVKRMRHL STGTMTGLAI QYALNIAFSE
160 170 180 190 200
AEGARPLREN VPRVIMIVTD GRPQDSVAEV AAKARDTGIL IFAIGVGQVD
210 220 230 240 250
FNTLKSIGSE PHEDHVFLVA NFSQIETLTS VFQKKLCTAH MCSTLEHNCA
260 270 280 290 300
HFCINIPGSY VCRCKQGYIL NSDQTTCRIQ DLCAMEDHNC EQLCVNVPGS
310 320 330 340 350
FVCQCYSGYA LAEDGKRCVA VDYCASENHG CEHECVNADG SYLCQCHEGF
360 370 380 390 400
ALNPDKKTCT KIDYCASSNH GCQHECVNTD DSYSCHCLKG FTLNPDKKTC
410 420 430 440 450
RRINYCALNK PGCEHECVNM EESYYCRCHR GYTLDPNGKT CSRVDHCAQQ
460 470 480 490 500
DHGCEQLCLN TEDSFVCQCS EGFLINEDLK TCSRVDYCLL SDHGCEYSCV
510 520 530 540 550
NMDRSFACQC PEGHVLRSDG KTCAKLDSCA LGDHGCEHSC VSSEDSFVCQ
560 570 580 590 600
CFEGYILRED GKTCRRKDVC QAIDHGCEHI CVNSDDSYTC ECLEGFRLAE
610 620 630 640 650
DGKRCRRKDV CKSTHHGCEH ICVNNGNSYI CKCSEGFVLA EDGRRCKKCT
660 670 680 690 700
EGPIDLVFVI DGSKSLGEEN FEVVKQFVTG IIDSLTISPK AARVGLLQYS
710 720 730 740 750
TQVHTEFTLR NFNSAKDMKK AVAHMKYMGK GSMTGLALKH MFERSFTQGE
760 770 780 790 800
GARPLSTRVP RAAIVFTDGR AQDDVSEWAS KAKANGITMY AVGVGKAIEE
810 820 830 840 850
ELQEIASEPT NKHLFYAEDF STMDEISEKL KKGICEALED SDGRQDSPAG
860 870 880 890 900
ELPKTVQQPT ESEPVTINIQ DLLSCSNFAV QHRYLFEEDN LLRSTQKLSH
910 920 930 940 950
STKPSGSPLE EKHDQCKCEN LIMFQNLANE EVRKLTQRLE EMTQRMEALE

NRLRYR
Length:956
Mass (Da):106,837
Last modified:June 28, 2011 - v4
Checksum:iD0868FBF62744EF2
GO
Isoform 2 (identifier: O00339-2) [UniParc]FASTAAdd to Basket

Also known as: Short

The sequence of this isoform differs from the canonical sequence as follows:
     861-879: Missing.

Show »
Length:937
Mass (Da):104,775
Checksum:i14FB20A486F3B9F0
GO
Isoform 3 (identifier: O00339-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     361-401: Missing.

Note: No experimental confirmation available.

Show »
Length:915
Mass (Da):102,232
Checksum:iB8C245C6EA17CDC1
GO
Isoform 4 (identifier: O00339-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-284: Missing.

Note: No experimental confirmation available.

Show »
Length:672
Mass (Da):75,251
Checksum:i933562EE766C3EC6
GO

Sequence cautioni

The sequence CAD38787.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti58 – 581L → P in BAF82410. (PubMed:14702039)Curated
Sequence conflicti594 – 5941E → V in AAC51260. (PubMed:11124542)Curated
Sequence conflicti644 – 6441R → G no nucleotide entry (PubMed:9083061)Curated
Sequence conflicti755 – 7551L → F in AAC51260. (PubMed:11124542)Curated
Sequence conflicti890 – 8901N → D in BAF82410. (PubMed:14702039)Curated
Sequence conflicti935 – 9351L → F no nucleotide entry (PubMed:9083061)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti14 – 141G → A.
Corresponds to variant rs35804177 [ dbSNP | Ensembl ].
VAR_055753
Natural varianti187 – 1871T → M.1 Publication
Corresponds to variant rs2290472 [ dbSNP | Ensembl ].
VAR_055754
Natural varianti356 – 3561K → E.2 Publications
Corresponds to variant rs1869609 [ dbSNP | Ensembl ].
VAR_021568
Natural varianti599 – 5991A → T.
Corresponds to variant rs35120814 [ dbSNP | Ensembl ].
VAR_055755
Natural varianti855 – 8551T → M.
Corresponds to variant rs2255317 [ dbSNP | Ensembl ].
VAR_055756
Natural varianti932 – 9321V → I.
Corresponds to variant rs17831160 [ dbSNP | Ensembl ].
VAR_055757

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 284284Missing in isoform 4. 1 PublicationVSP_014540Add
BLAST
Alternative sequencei361 – 40141Missing in isoform 3. 1 PublicationVSP_013284Add
BLAST
Alternative sequencei861 – 87919Missing in isoform 2. 3 PublicationsVSP_001399Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U69263 mRNA. Translation: AAC51260.2.
AY358895 mRNA. Translation: AAQ89254.1.
AL137638 mRNA. Translation: CAB70853.2.
AK289721 mRNA. Translation: BAF82410.1.
AL833931 mRNA. Translation: CAD38787.1. Different initiation.
AP002906 Genomic DNA. No translation available.
AP003352 Genomic DNA. No translation available.
BC010444 mRNA. Translation: AAH10444.1.
BC016394 mRNA. Translation: AAH16394.1.
CCDSiCCDS55264.1. [O00339-1]
CCDS55265.1. [O00339-2]
RefSeqiNP_002371.3. NM_002380.3. [O00339-1]
NP_085072.2. NM_030583.2. [O00339-2]
UniGeneiHs.189445.

Genome annotation databases

EnsembliENST00000254898; ENSP00000254898; ENSG00000132561. [O00339-1]
ENST00000520016; ENSP00000430487; ENSG00000132561. [O00339-1]
ENST00000521689; ENSP00000429977; ENSG00000132561. [O00339-2]
ENST00000522025; ENSP00000429010; ENSG00000132561. [O00339-4]
ENST00000524308; ENSP00000430221; ENSG00000132561. [O00339-3]
GeneIDi4147.
KEGGihsa:4147.
UCSCiuc003yic.3. human. [O00339-1]
uc003yid.3. human. [O00339-2]
uc010mbh.1. human. [O00339-3]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U69263 mRNA. Translation: AAC51260.2 .
AY358895 mRNA. Translation: AAQ89254.1 .
AL137638 mRNA. Translation: CAB70853.2 .
AK289721 mRNA. Translation: BAF82410.1 .
AL833931 mRNA. Translation: CAD38787.1 . Different initiation.
AP002906 Genomic DNA. No translation available.
AP003352 Genomic DNA. No translation available.
BC010444 mRNA. Translation: AAH10444.1 .
BC016394 mRNA. Translation: AAH16394.1 .
CCDSi CCDS55264.1. [O00339-1 ]
CCDS55265.1. [O00339-2 ]
RefSeqi NP_002371.3. NM_002380.3. [O00339-1 ]
NP_085072.2. NM_030583.2. [O00339-2 ]
UniGenei Hs.189445.

3D structure databases

ProteinModelPortali O00339.
SMRi O00339. Positions 57-647, 649-871.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 110317. 12 interactions.
DIPi DIP-47267N.
IntActi O00339. 6 interactions.
STRINGi 9606.ENSP00000254898.

PTM databases

PhosphoSitei O00339.

Proteomic databases

MaxQBi O00339.
PaxDbi O00339.
PRIDEi O00339.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000254898 ; ENSP00000254898 ; ENSG00000132561 . [O00339-1 ]
ENST00000520016 ; ENSP00000430487 ; ENSG00000132561 . [O00339-1 ]
ENST00000521689 ; ENSP00000429977 ; ENSG00000132561 . [O00339-2 ]
ENST00000522025 ; ENSP00000429010 ; ENSG00000132561 . [O00339-4 ]
ENST00000524308 ; ENSP00000430221 ; ENSG00000132561 . [O00339-3 ]
GeneIDi 4147.
KEGGi hsa:4147.
UCSCi uc003yic.3. human. [O00339-1 ]
uc003yid.3. human. [O00339-2 ]
uc010mbh.1. human. [O00339-3 ]

Organism-specific databases

CTDi 4147.
GeneCardsi GC08P098881.
HGNCi HGNC:6908. MATN2.
HPAi CAB033879.
MIMi 602108. gene.
neXtProti NX_O00339.
PharmGKBi PA30651.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG297993.
GeneTreei ENSGT00760000119000.
HOVERGENi HBG056906.
InParanoidi O00339.
OrthoDBi EOG70GMF3.
TreeFami TF330078.

Miscellaneous databases

ChiTaRSi MATN2. human.
GeneWikii MATN2.
GenomeRNAii 4147.
NextBioi 16292.
PROi O00339.
SOURCEi Search...

Gene expression databases

Bgeei O00339.
CleanExi HS_MATN2.
ExpressionAtlasi O00339. baseline and differential.
Genevestigatori O00339.

Family and domain databases

Gene3Di 1.20.5.30. 1 hit.
3.40.50.410. 2 hits.
InterProi IPR026823. cEGF.
IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR009030. Growth_fac_rcpt_N_dom.
IPR019466. Matrilin_coiled-coil_trimer.
IPR002035. VWF_A.
[Graphical view ]
Pfami PF12662. cEGF. 1 hit.
PF07645. EGF_CA. 1 hit.
PF10393. Matrilin_ccoil. 1 hit.
PF00092. VWA. 2 hits.
[Graphical view ]
SMARTi SM00181. EGF. 9 hits.
SM00179. EGF_CA. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view ]
SUPFAMi SSF53300. SSF53300. 2 hits.
SSF57184. SSF57184. 3 hits.
PROSITEi PS00010. ASX_HYDROXYL. 9 hits.
PS01186. EGF_2. 9 hits.
PS50026. EGF_3. 4 hits.
PS50234. VWFA. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structure of human matrilin-2, chromosome location of the MATN2 gene and conservation of an AT-AC intron in matrilin genes."
    Muratoglu S., Krysan K., Balazs M., Sheng H., Zakany R., Modis L., Kiss I., Deak F.
    Cytogenet. Cell Genet. 90:323-327(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT MET-187.
    Tissue: Brain.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4), VARIANT GLU-356.
    Tissue: Testis.
  5. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 242-956 (ISOFORM 1), VARIANT GLU-356.
    Tissue: Brain and Ovary.
  7. "Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily."
    Deak F., Piecha D., Bachrati C., Paulsson M., Kiss I.
    J. Biol. Chem. 272:9268-9274(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 644-956.

Entry informationi

Entry nameiMATN2_HUMAN
AccessioniPrimary (citable) accession number: O00339
Secondary accession number(s): A8K106
, E7EW74, E9PD48, E9PGL2, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 28, 2011
Last modified: November 26, 2014
This is version 145 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3