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Protein
Submitted name:

Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_g

Gene

PTGER3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • prostaglandin E receptor activity Source: UniProtKB

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin E receptor 3 (Subtype EP3), isoform CRA_gImported
Submitted name:
Prostaglandin E2 receptor EP3 subtypeImported
Submitted name:
Prostaglandin EP3 receptor subtype isoformImported
Gene namesi
Name:PTGER3Imported
ORF Names:hCG_1811960Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000050628.20.
HGNCiHGNC:9595. PTGER3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 75HelicalSequence analysisAdd BLAST24
Transmembranei87 – 112HelicalSequence analysisAdd BLAST26
Transmembranei132 – 153HelicalSequence analysisAdd BLAST22
Transmembranei173 – 194HelicalSequence analysisAdd BLAST22
Transmembranei228 – 253HelicalSequence analysisAdd BLAST26
Transmembranei284 – 307HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000050628.
PharmGKBiPA288.

Expressioni

Gene expression databases

BgeeiENSG00000050628.
ExpressionAtlasiO00325. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 346G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST282

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000119188.
HOVERGENiHBG052720.

Family and domain databases

InterProiView protein in InterPro
IPR001481. EP3_rcpt_2.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008365. Prostanoid_rcpt.
IPR001244. Prostglndn_DP_rcpt.
IPR000265. Prostglndn_EP3_rcpt.
PANTHERiPTHR11866. PTHR11866. 1 hit.
PTHR11866:SF10. PTHR11866:SF10. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00428. PROSTAGLNDNR.
PR01788. PROSTANOIDR.
PR00584. PRSTNOIDE32R.
PR00582. PRSTNOIDEP3R.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O00325-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKETRGYGGD APFCTRLNHS YTGMWAPERS AEARGNLTRP PGSGEDCGSV
60 70 80 90 100
SVAFPITMLL TGFVGNALAM LLVSRSYRRR ESKRKKSFLL CIGWLALTDL
110 120 130 140 150
VGQLLTTPVV IVVYLSKQRW EHIDPSGRLC TFFGLTMTVF GLSSLFIASA
160 170 180 190 200
MAVERALAIR APHWYASHMK TRATRAVLLG VWLAVLAFAL LPVLGVGQYT
210 220 230 240 250
VQWPGTWCFI STGRGGNGTS SSHNWGNLFF ASAFAFLGLL ALTVTFSCNL
260 270 280 290 300
ATIKALVSRC RAKATASQSS AQWGRITTET AIQLMGIMCV LSVCWSPLLI
310 320 330 340 350
MMLKMIFNQT SVEHCKTHTE KQKECNFFLI AVRLASLNQI LDPWVYLLLR
360 370 380 390 400
KILLRKFCQM RKRRLREQEM GPDGRCFCHA WRQVPRTWCS SHDREPCSVQ

LS
Length:402
Mass (Da):44,938
Last modified:July 1, 1997 - v1
Checksum:iD7449BB1538F12BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL031429 Genomic DNA. No translation available.
AL158087 Genomic DNA. No translation available.
KF454969 Genomic DNA. No translation available.
D86097 mRNA. Translation: BAA19958.1.
CH471059 Genomic DNA. Translation: EAX06442.1.
PIRiD55995.
RefSeqiNP_942011.1. NM_198718.1.
UniGeneiHs.445000.

Genome annotation databases

EnsembliENST00000361210; ENSP00000424340; ENSG00000050628.
GeneIDi5733.
UCSCiuc057hmo.1. human.

Similar proteinsi

Entry informationi

Entry nameiO00325_HUMAN
AccessioniPrimary (citable) accession number: O00325
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 1997
Last sequence update: July 1, 1997
Last modified: October 25, 2017
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported