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O00268

- TAF4_HUMAN

UniProt

O00268 - TAF4_HUMAN

Protein

Transcription initiation factor TFIID subunit 4

Gene

TAF4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 157 (01 Oct 2014)
      Sequence version 2 (07 Dec 2004)
      Previous versions | rss
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    Functioni

    Part of the TFIID complex, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Potentiates transcriptional activation by the AF-2S of the retinoic acid, vitamin D3 and thyroid hormone.

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB
    2. protein binding Source: UniProtKB
    3. sequence-specific DNA binding transcription factor activity Source: InterPro
    4. transcription coactivator activity Source: ProtInc

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: UniProtKB
    2. gene expression Source: Reactome
    3. ovarian follicle development Source: Ensembl
    4. positive regulation of transcription, DNA-templated Source: UniProtKB
    5. transcription elongation from RNA polymerase II promoter Source: Reactome
    6. transcription from RNA polymerase II promoter Source: Reactome
    7. transcription initiation from RNA polymerase II promoter Source: UniProtKB
    8. viral process Source: Reactome

    Keywords - Biological processi

    Host-virus interaction, Transcription, Transcription regulation

    Enzyme and pathway databases

    ReactomeiREACT_1655. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
    REACT_1851. RNA Polymerase II Transcription Initiation.
    REACT_2089. RNA Polymerase II Promoter Escape.
    REACT_22107. RNA Polymerase II Pre-transcription Events.
    REACT_6233. Transcription of the HIV genome.
    REACT_6253. RNA Polymerase II HIV Promoter Escape.
    REACT_6332. HIV Transcription Initiation.
    REACT_834. RNA Polymerase II Transcription Initiation And Promoter Clearance.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription initiation factor TFIID subunit 4
    Alternative name(s):
    RNA polymerase II TBP-associated factor subunit C
    TBP-associated factor 4
    Transcription initiation factor TFIID 130 kDa subunit
    Short name:
    TAF(II)130
    Short name:
    TAFII-130
    Short name:
    TAFII130
    Transcription initiation factor TFIID 135 kDa subunit
    Short name:
    TAF(II)135
    Short name:
    TAFII-135
    Short name:
    TAFII135
    Gene namesi
    Name:TAF4
    Synonyms:TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 20

    Organism-specific databases

    HGNCiHGNC:11537. TAF4.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. MLL1 complex Source: UniProtKB
    3. nucleoplasm Source: Reactome
    4. nucleus Source: HPA
    5. transcription factor TFIID complex Source: MGI
    6. transcription factor TFTC complex Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36312.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10851085Transcription initiation factor TFIID subunit 4PRO_0000118869Add
    BLAST

    Proteomic databases

    MaxQBiO00268.
    PaxDbiO00268.
    PRIDEiO00268.

    PTM databases

    PhosphoSiteiO00268.

    Expressioni

    Gene expression databases

    ArrayExpressiO00268.
    BgeeiO00268.
    CleanExiHS_TAF4.
    GenevestigatoriO00268.

    Organism-specific databases

    HPAiCAB031484.
    HPA008599.

    Interactioni

    Subunit structurei

    TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H, TAF2, TAF4, TAF5, GCN5L2/GCN5, TAF10 and TRRAP. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with ATF7; the interaction inhibits ATF7-mediated tranactivation. Interacts with SV40 Large T antigen.6 Publications

    Protein-protein interaction databases

    BioGridi112737. 37 interactions.
    DIPiDIP-35350N.
    IntActiO00268. 8 interactions.
    MINTiMINT-236922.
    STRINGi9606.ENSP00000252996.

    Structurei

    Secondary structure

    1
    1085
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi585 – 60723
    Beta strandi609 – 6124
    Helixi614 – 62815
    Helixi634 – 64411
    Helixi653 – 66614
    Helixi671 – 6777
    Helixi875 – 88713
    Turni888 – 8903
    Helixi898 – 91821

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1H3OX-ray2.30A/C872-945[»]
    2P6VX-ray2.00A575-679[»]
    ProteinModelPortaliO00268.
    SMRiO00268. Positions 583-679, 872-919.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO00268.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini590 – 68798TAFHPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi39 – 424Poly-His
    Compositional biasi52 – 576Poly-Ala
    Compositional biasi98 – 1014Poly-Gly
    Compositional biasi142 – 1487Poly-Ala
    Compositional biasi270 – 2778Poly-Pro
    Compositional biasi333 – 3397Poly-Ala
    Compositional biasi682 – 6854Poly-Pro
    Compositional biasi810 – 8156Poly-Ala
    Compositional biasi830 – 8334Poly-Asp

    Sequence similaritiesi

    Belongs to the TAF4 family.Curated
    Contains 1 TAFH (NHR1) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG237595.
    HOGENOMiHOG000154502.
    HOVERGENiHBG058585.
    InParanoidiO00268.
    KOiK03129.
    OMAiVVMNSHH.
    PhylomeDBiO00268.
    TreeFamiTF316520.

    Family and domain databases

    Gene3Di1.10.20.10. 1 hit.
    InterProiIPR009072. Histone-fold.
    IPR007900. TAF4.
    IPR003894. TAFH_NHR1.
    [Graphical view]
    PfamiPF05236. TAF4. 1 hit.
    PF07531. TAFH. 1 hit.
    [Graphical view]
    SMARTiSM00549. TAFH. 1 hit.
    [Graphical view]
    SUPFAMiSSF47113. SSF47113. 1 hit.
    PROSITEiPS51119. TAFH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O00268-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAGSDLLDE VFFNSEVDEK VVSDLVGSLE SQLAASAAHH HHLAPRTPEV     50
    RAAAAGALGN HVVSGSPAGA AGAGPAAPAE GAPGAAPEPP PAGRARPGGG 100
    GPQRPGPPSP RRPLVPAGPA PPAAKLRPPP EGSAGSCAPV PAAAAVAAGP 150
    EPAPAGPAKP AGPAALAARA GPGPGPGPGP GPGPGPGKPA GPGAAQTLNG 200
    SAALLNSHHA AAPAVSLVNN GPAALLPLPK PAAPGTVIQT PPFVGAAAPP 250
    APAAPSPPAA PAPAAPAAAP PPPPPAPATL ARPPGHPAGP PTAAPAVPPP 300
    AAAQNGGSAG AAPAPAPAAG GPAGVSGQPG PGAAAAAPAP GVKAESPKRV 350
    VQAAPPAAQT LAASGPASTA ASMVIGPTMQ GALPSPAAVP PPAPGTPTGL 400
    PKGAAGAVTQ SLSRTPTATT SGIRATLTPT VLAPRLPQPP QNPTNIQNFQ 450
    LPPGMVLVRS ENGQLLMIPQ QALAQMQAQA HAQPQTTMAP RPATPTSAPP 500
    VQISTVQAPG TPIIARQVTP TTIIKQVSQA QTTVQPSATL QRSPGVQPQL 550
    VLGGAAQTAS LGTATAVQTG TPQRTVPGAT TTSSAATETM ENVKKCKNFL 600
    STLIKLASSG KQSTETAANV KELVQNLLDG KIEAEDFTSR LYRELNSSPQ 650
    PYLVPFLKRS LPALRQLTPD SAAFIQQSQQ QPPPPTSQAT TALTAVVLSS 700
    SVQRTAGKTA ATVTSALQPP VLSLTQPTQV GVGKQGQPTP LVIQQPPKPG 750
    ALIRPPQVTL TQTPMVALRQ PHNRIMLTTP QQIQLNPLQP VPVVKPAVLP 800
    GTKALSAVSA QAAAAQKNKL KEPGGGSFRD DDDINDVASM AGVNLSEESA 850
    RILATNSELV GTLTRSCKDE TFLLQAPLQR RILEIGKKHG ITELHPDVVS 900
    YVSHATQQRL QNLVEKISET AQQKNFSYKD DDRYEQASDV RAQLKFFEQL 950
    DQIEKQRKDE QEREILMRAA KSRSRQEDPE QLRLKQKAKE MQQQELAQMR 1000
    QRDANLTALA AIGPRKKRKV DCPGPGSGAE GSGPGSVVPG SSGVGTPRQF 1050
    TRQRITRVNL RDLIFCLENE RETSHSLLLY KAFLK 1085
    Length:1,085
    Mass (Da):110,114
    Last modified:December 7, 2004 - v2
    Checksum:iBC2F5B5F143DB145
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti105 – 11713PGPPS…PLVPA → GRGLLQQRGGRES in AAC50901. (PubMed:8942982)CuratedAdd
    BLAST
    Sequence conflicti136 – 1361S → A in CAA72189. (PubMed:9192867)Curated
    Sequence conflicti136 – 1361S → A in AAC50901. (PubMed:8942982)Curated
    Sequence conflicti186 – 1872Missing in CAA72189. (PubMed:9192867)Curated
    Sequence conflicti186 – 1872Missing in AAC50901. (PubMed:8942982)Curated
    Sequence conflicti235 – 26632Missing in AAC50901. (PubMed:8942982)CuratedAdd
    BLAST
    Sequence conflicti295 – 2951P → L in AAC50901. (PubMed:8942982)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti651 – 6511P → L.
    Corresponds to variant rs6089604 [ dbSNP | Ensembl ].
    VAR_052258

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y11354 mRNA. Translation: CAA72189.1.
    AY623115 Genomic DNA. Translation: AAT38111.1.
    AL109911, AL137077 Genomic DNA. Translation: CAI19182.1.
    AL137077, AL109911 Genomic DNA. Translation: CAI11045.1.
    CH471077 Genomic DNA. Translation: EAW75407.1.
    U75308 mRNA. Translation: AAC50901.1.
    CCDSiCCDS33500.1.
    RefSeqiNP_003176.2. NM_003185.3.
    UniGeneiHs.18857.

    Genome annotation databases

    EnsembliENST00000252996; ENSP00000252996; ENSG00000130699.
    GeneIDi6874.
    KEGGihsa:6874.
    UCSCiuc002ybs.3. human.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Web resourcesi

    NIEHS-SNPs

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Y11354 mRNA. Translation: CAA72189.1 .
    AY623115 Genomic DNA. Translation: AAT38111.1 .
    AL109911 , AL137077 Genomic DNA. Translation: CAI19182.1 .
    AL137077 , AL109911 Genomic DNA. Translation: CAI11045.1 .
    CH471077 Genomic DNA. Translation: EAW75407.1 .
    U75308 mRNA. Translation: AAC50901.1 .
    CCDSi CCDS33500.1.
    RefSeqi NP_003176.2. NM_003185.3.
    UniGenei Hs.18857.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1H3O X-ray 2.30 A/C 872-945 [» ]
    2P6V X-ray 2.00 A 575-679 [» ]
    ProteinModelPortali O00268.
    SMRi O00268. Positions 583-679, 872-919.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112737. 37 interactions.
    DIPi DIP-35350N.
    IntActi O00268. 8 interactions.
    MINTi MINT-236922.
    STRINGi 9606.ENSP00000252996.

    PTM databases

    PhosphoSitei O00268.

    Proteomic databases

    MaxQBi O00268.
    PaxDbi O00268.
    PRIDEi O00268.

    Protocols and materials databases

    DNASUi 6874.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000252996 ; ENSP00000252996 ; ENSG00000130699 .
    GeneIDi 6874.
    KEGGi hsa:6874.
    UCSCi uc002ybs.3. human.

    Organism-specific databases

    CTDi 6874.
    GeneCardsi GC20M060529.
    H-InvDB HIX0015971.
    HIX0174705.
    HGNCi HGNC:11537. TAF4.
    HPAi CAB031484.
    HPA008599.
    MIMi 601796. gene.
    neXtProti NX_O00268.
    PharmGKBi PA36312.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG237595.
    HOGENOMi HOG000154502.
    HOVERGENi HBG058585.
    InParanoidi O00268.
    KOi K03129.
    OMAi VVMNSHH.
    PhylomeDBi O00268.
    TreeFami TF316520.

    Enzyme and pathway databases

    Reactomei REACT_1655. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
    REACT_1851. RNA Polymerase II Transcription Initiation.
    REACT_2089. RNA Polymerase II Promoter Escape.
    REACT_22107. RNA Polymerase II Pre-transcription Events.
    REACT_6233. Transcription of the HIV genome.
    REACT_6253. RNA Polymerase II HIV Promoter Escape.
    REACT_6332. HIV Transcription Initiation.
    REACT_834. RNA Polymerase II Transcription Initiation And Promoter Clearance.

    Miscellaneous databases

    ChiTaRSi TAF4. human.
    EvolutionaryTracei O00268.
    GeneWikii TAF4.
    GenomeRNAii 6874.
    NextBioi 26837.
    PROi O00268.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi O00268.
    Bgeei O00268.
    CleanExi HS_TAF4.
    Genevestigatori O00268.

    Family and domain databases

    Gene3Di 1.10.20.10. 1 hit.
    InterProi IPR009072. Histone-fold.
    IPR007900. TAF4.
    IPR003894. TAFH_NHR1.
    [Graphical view ]
    Pfami PF05236. TAF4. 1 hit.
    PF07531. TAFH. 1 hit.
    [Graphical view ]
    SMARTi SM00549. TAFH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47113. SSF47113. 1 hit.
    PROSITEi PS51119. TAFH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells."
      Mengus G., May M., Carre L., Chambon P., Davidson I.
      Genes Dev. 11:1381-1395(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. NIEHS SNPs program
      Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100."
      Tanese N., Saluja D., Vassallo M.F., Chen J.-L., Admon A.
      Proc. Natl. Acad. Sci. U.S.A. 93:13611-13616(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 105-1085, PARTIAL PROTEIN SEQUENCE.
    6. "TAF-like function of SV40 large T antigen."
      Damania B., Alwine J.C.
      Genes Dev. 10:1369-1381(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH SV40 LARGE T ANTIGEN.
    7. "Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction."
      Brand M., Yamamoto K., Staub A., Tora L.
      J. Biol. Chem. 274:18285-18289(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE TFTC-HAT COMPLEX WITH TAF5L; TAF6L; TADA3L; SUPT3H; TAF2; TAF5; TRRAP; GCN5L2 AND TAF10.
    8. "Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis."
      Cavusoglu N., Brand M., Tora L., van Dorsselaer A.
      Proteomics 3:217-223(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE TFTC-HAT COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
    9. "Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF."
      Dou Y., Milne T.A., Tackett A.J., Smith E.R., Fukuda A., Wysocka J., Allis C.D., Chait B.T., Hess J.L., Roeder R.G.
      Cell 121:873-885(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE MLL1/MLL COMPLEX.
    10. "A functional interaction between ATF7 and TAF12 that is modulated by TAF4."
      Hamard P.J., Dalbies-Tran R., Hauss C., Davidson I., Kedinger C., Chatton B.
      Oncogene 24:3472-3483(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH ATF7.
    11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    12. "The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs."
      Gangloff Y.-G., Werten S., Romier C., Carre L., Poch O., Moras D., Davidson I.
      Mol. Cell. Biol. 20:340-351(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 872-920 IN COMPLEX WITH TAF12.

    Entry informationi

    Entry nameiTAF4_HUMAN
    AccessioniPrimary (citable) accession number: O00268
    Secondary accession number(s): A6NGD9
    , Q5TBP6, Q99721, Q9BR40, Q9BX42
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: December 7, 2004
    Last modified: October 1, 2014
    This is version 157 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 20
      Human chromosome 20: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3