Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

3-phytase B

Gene

phyB

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of inorganic orthophosphate from phytate.

Catalytic activityi

Myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80NucleophileBy similarity1
Active sitei358Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BRENDAi3.1.3.26. 517.
3.1.3.8. 517.

Names & Taxonomyi

Protein namesi
Recommended name:
3-phytase B (EC:3.1.3.8)
Alternative name(s):
3 phytase B
Myo-inositol hexakisphosphate phosphohydrolase B
Myo-inositol-hexaphosphate 3-phosphohydrolase B
Gene namesi
Name:phyB
ORF Names:AN1685
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome VII
  • UP000005890 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000002397620 – 4633-phytase BAdd BLAST444

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi26N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi41N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi103N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi203N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi226N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi331N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi335N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi372N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi162425.CADANIAP00008327.

Structurei

3D structure databases

ProteinModelPortaliO00093.
SMRiO00093.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000189493.
InParanoidiO00093.
OMAiFSHDNDM.
OrthoDBiEOG092C1SWD.

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
InterProiView protein in InterPro
IPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
PfamiView protein in Pfam
PF00328. His_Phos_2. 1 hit.
PIRSFiPIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiView protein in PROSITE
PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O00093-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFFTVALSL YYLLSRVSTQ APVVQNHSCN TADGGYQCFP NVSHVWGQYS
60 70 80 90 100
PYFSIEQESA ISEDVPHGCE VTFVQVLSRH GARYPTESKS KAYSGLIEAI
110 120 130 140 150
QKNATSFWGQ YAFLESYNYT LGADDLTIFG ENQMVDSGAK FYRRYKNLAR
160 170 180 190 200
KNTPFIRASG SDRVVASAEK FINGFRKAQL HDHGSKRATP VVNVIIPEID
210 220 230 240 250
GFNNTLDHST CVSFENDERA DEIEANFTAI MGPPIRKRLE NDLPGIKLTN
260 270 280 290 300
ENVIYLMDMC SFDTMARTAH GTELSPFCAI FTEKEWLQYD YLQSLSKYYG
310 320 330 340 350
YGAGSPLGPA QGIGFTNELI ARLTQSPVQD NTSTNHTLDS NPATFPLDRK
360 370 380 390 400
LYADFSHDNS MISIFFAMGL YNGTQPLSMD SVESIQEMDG YAASWTVPFG
410 420 430 440 450
ARAYFELMQC EKKEPLVRVL VNDRVVPLHG CAVDKFGRCT LDDWVEGLNF
460
ARSGGNWKTC FTL
Length:463
Mass (Da):51,816
Last modified:May 1, 2007 - v2
Checksum:i1D6BC0B0DA14F0D9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti19T → A in AAB96871 (PubMed:9349716).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U59803 Genomic DNA. Translation: AAB96871.1.
AACD01000026 Genomic DNA. Translation: EAA64805.1.
BN001307 Genomic DNA. Translation: CBF85365.1.
RefSeqiXP_659289.1. XM_654197.1.

Genome annotation databases

EnsemblFungiiCADANIAT00008327; CADANIAP00008327; CADANIAG00008327.
EAA64805; EAA64805; AN1685.2.
GeneIDi2874708.
KEGGiani:AN1685.2.

Entry informationi

Entry nameiPHYB_EMENI
AccessioniPrimary (citable) accession number: O00093
Secondary accession number(s): C8VNT4, Q5BCP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: May 1, 2007
Last modified: October 25, 2017
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families