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O00088

- GLNA_AGABI

UniProt

O00088 - GLNA_AGABI

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Protein

Glutamine synthetase

Gene
glnA
Organism
Agaricus bisporus (White button mushroom)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
OrganismiAgaricus bisporus (White button mushroom)
Taxonomic identifieri5341 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 354354Glutamine synthetasePRO_0000153149Add
BLAST

Interactioni

Subunit structurei

Homooctamer By similarity.

Structurei

3D structure databases

ProteinModelPortaliO00088.
SMRiO00088. Positions 8-354.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OMAiIIVETTC.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O00088-1 [UniParc]FASTAAdd to Basket

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MANTYHNDLL APYLSLDQGD KIQAEYVWID GDGGLRCKTT TVSKKVTDIG    50
QLRIWDFDGS STNQAPGHDS DVYLRPAAIF KDPFRGGDNI LVLAETYNND 100
GTPNRTNHRH HAKKVFDEAK EHEPWFGLEQ EYTLFDADDQ PYGWPKGGFP 150
GPQGPYYCGA GTGKVFARDL IEAHYRACLY AGINISGINA EVMPSQWEFQ 200
VGPCEGISMG DHLWMARYLL VRIAEQWGVK VSFHPKPLKG EWNGAGCHTN 250
FSTKAMREAG GMKFIEDAIE KLAKRHDEHI AVYGEDNDLR LTGRHETGHI 300
SNFSSGVANR GASIRVPRHV ASQGYGYLED RRPASNIDPY RVTSIIAETT 350
ILDK 354
Length:354
Mass (Da):39,533
Last modified:July 1, 1997 - v1
Checksum:i93CDA55EC287B8A2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y12704 Genomic DNA. Translation: CAA73235.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y12704 Genomic DNA. Translation: CAA73235.1 .

3D structure databases

ProteinModelPortali O00088.
SMRi O00088. Positions 8-354.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OMAi IIVETTC.

Family and domain databases

Gene3Di 3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of the glnA gene encoding glutamine synthetase from the edible mushroom Agaricus bisporus."
    Kersten M.A.S.H., Mueller Y., Op den Camp H.J.M., Vogels G.D., van Griensven L.J.L.D., Visser J., Schaap P.J.
    Mol. Gen. Genet. 256:179-186(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Horst H39.

Entry informationi

Entry nameiGLNA_AGABI
AccessioniPrimary (citable) accession number: O00088
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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