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O00088

- GLNA_AGABI

UniProt

O00088 - GLNA_AGABI

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Protein

Glutamine synthetase

Gene

glnA

Organism
Agaricus bisporus (White button mushroom)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
OrganismiAgaricus bisporus (White button mushroom)
Taxonomic identifieri5341 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 354354Glutamine synthetasePRO_0000153149Add
BLAST

Interactioni

Subunit structurei

Homooctamer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO00088.
SMRiO00088. Positions 8-354.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

OMAiIIVETTC.

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O00088 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MANTYHNDLL APYLSLDQGD KIQAEYVWID GDGGLRCKTT TVSKKVTDIG
60 70 80 90 100
QLRIWDFDGS STNQAPGHDS DVYLRPAAIF KDPFRGGDNI LVLAETYNND
110 120 130 140 150
GTPNRTNHRH HAKKVFDEAK EHEPWFGLEQ EYTLFDADDQ PYGWPKGGFP
160 170 180 190 200
GPQGPYYCGA GTGKVFARDL IEAHYRACLY AGINISGINA EVMPSQWEFQ
210 220 230 240 250
VGPCEGISMG DHLWMARYLL VRIAEQWGVK VSFHPKPLKG EWNGAGCHTN
260 270 280 290 300
FSTKAMREAG GMKFIEDAIE KLAKRHDEHI AVYGEDNDLR LTGRHETGHI
310 320 330 340 350
SNFSSGVANR GASIRVPRHV ASQGYGYLED RRPASNIDPY RVTSIIAETT

ILDK
Length:354
Mass (Da):39,533
Last modified:July 1, 1997 - v1
Checksum:i93CDA55EC287B8A2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y12704 Genomic DNA. Translation: CAA73235.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y12704 Genomic DNA. Translation: CAA73235.1 .

3D structure databases

ProteinModelPortali O00088.
SMRi O00088. Positions 8-354.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

OMAi IIVETTC.

Family and domain databases

Gene3Di 3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of the glnA gene encoding glutamine synthetase from the edible mushroom Agaricus bisporus."
    Kersten M.A.S.H., Mueller Y., Op den Camp H.J.M., Vogels G.D., van Griensven L.J.L.D., Visser J., Schaap P.J.
    Mol. Gen. Genet. 256:179-186(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Horst H39.

Entry informationi

Entry nameiGLNA_AGABI
AccessioniPrimary (citable) accession number: O00088
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3