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O00088 (GLNA_AGABI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine synthetase

Short name=GS
EC=6.3.1.2
Alternative name(s):
Glutamate--ammonia ligase
Gene names
Name:glnA
OrganismAgaricus bisporus (White button mushroom)
Taxonomic identifier5341 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

Subunit structure

Homooctamer By similarity.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the glutamine synthetase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
Gene Ontology (GO)
   Biological_processglutamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamate-ammonia ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Glutamine synthetase
PRO_0000153149

Sequences

Sequence LengthMass (Da)Tools
O00088 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: 93CDA55EC287B8A2

FASTA35439,533
        10         20         30         40         50         60 
MANTYHNDLL APYLSLDQGD KIQAEYVWID GDGGLRCKTT TVSKKVTDIG QLRIWDFDGS 

        70         80         90        100        110        120 
STNQAPGHDS DVYLRPAAIF KDPFRGGDNI LVLAETYNND GTPNRTNHRH HAKKVFDEAK 

       130        140        150        160        170        180 
EHEPWFGLEQ EYTLFDADDQ PYGWPKGGFP GPQGPYYCGA GTGKVFARDL IEAHYRACLY 

       190        200        210        220        230        240 
AGINISGINA EVMPSQWEFQ VGPCEGISMG DHLWMARYLL VRIAEQWGVK VSFHPKPLKG 

       250        260        270        280        290        300 
EWNGAGCHTN FSTKAMREAG GMKFIEDAIE KLAKRHDEHI AVYGEDNDLR LTGRHETGHI 

       310        320        330        340        350 
SNFSSGVANR GASIRVPRHV ASQGYGYLED RRPASNIDPY RVTSIIAETT ILDK 

« Hide

References

[1]"Molecular characterization of the glnA gene encoding glutamine synthetase from the edible mushroom Agaricus bisporus."
Kersten M.A.S.H., Mueller Y., Op den Camp H.J.M., Vogels G.D., van Griensven L.J.L.D., Visser J., Schaap P.J.
Mol. Gen. Genet. 256:179-186(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Horst H39.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y12704 Genomic DNA. Translation: CAA73235.1.

3D structure databases

ProteinModelPortalO00088.
SMRO00088. Positions 8-354.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OMAIIVETTC.

Family and domain databases

Gene3D3.30.590.10. 1 hit.
InterProIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMSSF54368. SSF54368. 1 hit.
PROSITEPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLNA_AGABI
AccessionPrimary (citable) accession number: O00088
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 1, 1997
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families