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Protein

Tubulin alpha chain

Gene

FOC1_g10015957

Organism
Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin alpha chainUniRule annotation
Gene namesi
ORF Names:FOC1_g10015957Imported
OrganismiFusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus)Imported
Taxonomic identifieri1229664 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaeFusariumFusarium oxysporum species complex
Proteomesi
  • UP000016928 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonSAAS annotation, MicrotubuleUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 247TubulinInterPro annotationAdd BLAST198
Domaini249 – 398Tubulin_CInterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the tubulin family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiEOG092C2JRV.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiView protein in InterPro
IPR002452. Alpha_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
PANTHERiPTHR11588. PTHR11588. 1 hit.
PfamiView protein in Pfam
PF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
PRINTSiPR01162. ALPHATUBULIN.
PR01161. TUBULIN.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEiView protein in PROSITE
PS00227. TUBULIN. 1 hit.

Sequencei

Sequence statusi: Complete.

N4TU63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGEILHLHL GQAGTQLGNS AWELYLLEHG LGPDGRPDPN APDIGDPGSF
60 70 80 90 100
ETFFTETSSG KHVPRSLFVD LDPSPIDEIR TGEYRNLFHP ELLISGKEDA
110 120 130 140 150
ANNYARGHYT IGKEMVDNVI DRIRRVADNC QSLQGFLIFH SFGGGTGSGF
160 170 180 190 200
GALLLERLST EYGKKSKLEF AVYPAPRTST AVVEPYNAVL STHSTIENSD
210 220 230 240 250
CTFLVDNEAV YDICRRNLDI PRPSYEHLNR LIAQVVSSIT SSLRFDGALN
260 270 280 290 300
VDLNEFQTNL VPYPRIHYPL ISYAPVISSA KSEHESFKVQ ELTFQCFEPN
310 320 330 340 350
NQMVVCDPRN GKYMAVALLY RGDVVPRDCN AAIAALKAKA SFNLVEWCPT
360 370 380 390 400
GFKLGINYQK PMAVPAAPEA GGLAPVKRSV SMLSNTTAIA EAWSRLDYKF
410 420 430 440 450
DLMHSKRAFV HWYVGEGMEE GEFTEAREDL AALEKDYEEV AADSFEPEEE

LEY
Length:453
Mass (Da):50,379
Last modified:June 26, 2013 - v1
Checksum:i2F773933BD767149
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB731261 Genomic DNA. Translation: ENH61150.1.

Genome annotation databases

EnsemblFungiiENH61150; ENH61150; FOC1_g10015957.

Similar proteinsi

Entry informationi

Entry nameiN4TU63_FUSC1
AccessioniPrimary (citable) accession number: N4TU63
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: October 25, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported