ID   N0CTR6_STRMI            Unreviewed;       636 AA.
AC   N0CTR6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   ORFNames=SFUL_4680 {ECO:0000313|EMBL:AGK79576.1};
OS   Streptomyces microflavus DSM 40593.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1303692 {ECO:0000313|EMBL:AGK79576.1, ECO:0000313|Proteomes:UP000013304};
RN   [1] {ECO:0000313|EMBL:AGK79576.1, ECO:0000313|Proteomes:UP000013304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40593 {ECO:0000313|EMBL:AGK79576.1,
RC   ECO:0000313|Proteomes:UP000013304};
RA   Myronovskyi M., Tokovenko B., Manderscheid N., Petzke L., Luzhetskyy A.;
RT   "Complete genome sequence of Streptomyces fulvissimus.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC       {ECO:0000256|ARBA:ARBA00009348}.
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DR   EMBL; CP005080; AGK79576.1; -; Genomic_DNA.
DR   RefSeq; WP_015610899.1; NC_021177.1.
DR   AlphaFoldDB; N0CTR6; -.
DR   KEGG; sfi:SFUL_4680; -.
DR   PATRIC; fig|1303692.3.peg.4694; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_430157_0_0_11; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000013304; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd00110; LamG; 1.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006558; LamG-like.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   Pfam; PF13385; Laminin_G_3; 1.
DR   SMART; SM00282; LamG; 1.
DR   SMART; SM00560; LamGL; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           41..636
FT                   /note="exo-alpha-sialidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004106015"
FT   DOMAIN          442..618
FT                   /note="Laminin G"
FT                   /evidence="ECO:0000259|PROSITE:PS50025"
SQ   SEQUENCE   636 AA;  66336 MW;  2D290CD15F27A94F CRC64;
     MRFPGRPPHP RRRRTRPLTA ALTLTLAATA LTAPASPAAA AVPAAVTTPF KAGTEGYRCF
     RIPALVTTPS GALLAFAEGR VATCSDIGHN DIVMRKSTDG GRSWGPLKVV AGAADEDAHG
     NPAPVVDTAT GRVSLLYATG GWSGTPSAPV RGPRSLRVVH SVDDGAGWTA GAPLPHLKPA
     DRAWISTGPG HGIQLARGPH RGRLVVPGDY TTTGGRAGGQ LYVSDDGGLT WALGAHADVD
     RATSAFPAEL SVAETTGGGV YVNARSSARC GTNDHRTAAT SADGGNTFAA PFSPVPGLDT
     PPVSGSLLRL HAKELGAAQD RLLFSAPSRL GPHTLEDRRE LAIRSSYDEG RSWRTVGTVV
     TPGRSGYSDL ALVPGGAIGV LYETAGNIPH SDIAFTSFTE GQMDAAQREL RLPRTSDTGP
     GQYGNHAVVH GGAQLGTRNS GKAMTFDGQD DYLRLVSCSD SLRLGAGDFT LTAWFRHTAT
     TGALPIVWGY GMGSGVQQFW LRAEPGQGRI RAAIDTGTAY AEAKTTSSYN DGQWHHTVVK
     RQSGRLTLSV DGGQEFGAAA PAGSISPPAE FSVHIGARPD FPNQPAGVTE LFRGGLDDIR
     IYGRGLTAQE AAQVKAGALD VANEEERVRL GFSSIW
//