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N0CJ65 (N0CJ65_9ACTO) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 7. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
ORF Names:SFUL_761 EMBL AGK75745.1
OrganismStreptomyces fulvissimus DSM 40593 [Complete proteome] EMBL AGK75745.1
Taxonomic identifier1303692 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length511 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617 HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196 HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2101N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2081ATP By similarity HAMAP-Rule MF_00407
Binding site2151ATP By similarity HAMAP-Rule MF_00407
Binding site2301ATP By similarity HAMAP-Rule MF_00407
Binding site2591ATP By similarity HAMAP-Rule MF_00407
Binding site2991ATP By similarity HAMAP-Rule MF_00407
Binding site3771ATP By similarity HAMAP-Rule MF_00407
Binding site3831ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
N0CJ65 [UniParc].

Last modified June 26, 2013. Version 1.
Checksum: 0F52184B683C4F4C

FASTA51154,632
        10         20         30         40         50         60 
MLLAELAQVS LEVAATSARS KKVALLAALF RDAGPDDVPV VIPYLAGRLP QGRIGVGWRS 

        70         80         90        100        110        120 
LGDPVEPASE PTLTVTGVDA ELTALAAVSG SGSQALRRER LRALFAAATA DEQHFLRALL 

       130        140        150        160        170        180 
TGEVRQGALD AVAADALARA AEAPPADVRR AVMLAGSLQE VARTLLAEGP GALAAFRLTV 

       190        200        210        220        230        240 
GRPVQPMLAH TAASVTEAVD KLGPCAVEEK LDGIRVQVHR DGDRVRAFTR TLDDITDRLP 

       250        260        270        280        290        300 
ELVTAVAALE TGRFILDGEV IALGDDGRPR PFQETAARVG SRRDVAAAAA GVPIVPVFFD 

       310        320        330        340        350        360 
ALSADGEDLL DLPYTERHTA LARLVPEHLR VRRALVPEAG DADARRAAEA FLAETLERGH 

       370        380        390        400        410        420 
EGVVVKDLAA AYSAGRRGAS WLKVKPVHTL DLVVLAAEWG SGRRTGKLSN LHLGARRPDG 

       430        440        450        460        470        480 
TFAMLGKTFK GLTDALLEWQ TEKLRELATG EDGHVVTVRP ELVVEIAYDG LQRSTRYPAG 

       490        500        510 
VTLRFARVLR YREDKTAQEA DTVETVLSRQ R 

« Hide

References

[1]"Complete genome sequence of Streptomyces fulvissimus."
Myronovskyi M., Tokovenko B., Manderscheid N., Petzke L., Luzhetskyy A.
Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DSM 40593 EMBL AGK75745.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP005080 Genomic DNA. Translation: AGK75745.1.
RefSeqYP_007929630.1. NC_021177.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAGK75745; AGK75745; SFUL_761.
GeneID15400544.
KEGGsfi:SFUL_761.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01971.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameN0CJ65_9ACTO
AccessionPrimary (citable) accession number: N0CJ65
Entry history
Integrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: February 19, 2014
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)