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Protein

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

Gene

fabZ

Organism
Mannheimia haemolytica M42548
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.UniRule annotationSAAS annotation

Catalytic activityi

A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H2O.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei57UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processLipid A biosynthesisUniRule annotationSAAS annotation, Lipid biosynthesis, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZUniRule annotation (EC:4.2.1.59UniRule annotation)
Alternative name(s):
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydrataseUniRule annotation
Short name:
(3R)-hydroxymyristoyl-ACP dehydraseUniRule annotation
Beta-hydroxyacyl-ACP dehydrataseUniRule annotation
Gene namesi
Name:fabZUniRule annotationImported
ORF Names:MHH_c16060Imported
OrganismiMannheimia haemolytica M42548Imported
Taxonomic identifieri1316932 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeMannheimia
Proteomesi
  • UP000012987 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliM9X0D0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 144FabAInterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the thioester dehydratase family. FabZ subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK02372.
OrthoDBiPOG091H005Q.

Family and domain databases

HAMAPiMF_00406. FabZ. 1 hit.
InterProiView protein in InterPro
IPR013114. FabA_FabZ.
IPR010084. FabZ.
IPR029069. HotDog_dom_sf.
PfamiView protein in Pfam
PF07977. FabA. 1 hit.
SUPFAMiSSF54637. SSF54637. 1 hit.
TIGRFAMsiTIGR01750. fabZ. 1 hit.

Sequencei

Sequence statusi: Complete.

M9X0D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTENREPNI IEVTEIMDML PHRYPFLLVD RVTDYEEGKW LKAIKNVTFN
60 70 80 90 100
EPCFTGHFPG APIFPGVLIL EAMAQATGVL AVATYGKLSE DELYYFAAID
110 120 130 140 150
NARFKRPVVP GDQLQLEVEF LKEVRGITKF TGKAYVDGKL VCEADLMCAR

RK
Length:152
Mass (Da):17,207
Last modified:June 26, 2013 - v1
Checksum:i51BB227BD3613C7E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP005383 Genomic DNA. Translation: AGK02056.1.
RefSeqiWP_006248428.1. NC_021082.1.

Genome annotation databases

EnsemblBacteriaiAGK02056; AGK02056; MHH_c16060.
GeneIDi15339338.
KEGGimhx:MHH_c16060.
PATRICifig|1316932.3.peg.1567.

Similar proteinsi

Entry informationi

Entry nameiM9X0D0_MANHA
AccessioniPrimary (citable) accession number: M9X0D0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: November 22, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported