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Protein

Protein tweety homolog

Gene

TTYH2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable chloride channel.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionChloride channelUniRule annotation, Ion channel
Biological processIon transport, Transport
LigandChloride

Names & Taxonomyi

Protein namesi
Recommended name:
Protein tweety homologUniRule annotation
Gene namesi
Name:TTYH2Imported
Synonyms:BG00376Imported, Dmel\CG3638Imported, EG:33C11.3Imported
ORF Names:CG3638Imported, Dmel_CG3638Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0261444. CG3638.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 62HelicalUniRule annotationAdd BLAST24
Transmembranei83 – 100HelicalUniRule annotationAdd BLAST18
Transmembranei212 – 236HelicalUniRule annotationAdd BLAST25
Transmembranei243 – 266HelicalUniRule annotationAdd BLAST24
Transmembranei385 – 408HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0261444.
ExpressionAtlasiM9PGE0. differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the tweety family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000010182.
OrthoDBiEOG091G0IBL.

Family and domain databases

CDDicd07912. Tweety_N. 1 hit.
InterProiView protein in InterPro
IPR006990. Tweety.
PANTHERiPTHR12424. PTHR12424. 1 hit.
PfamiView protein in Pfam
PF04906. Tweety. 1 hit.

Sequencei

Sequence statusi: Complete.

M9PGE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQPSILVKI LHSIPHVNYT FRRVNDTFNP DSDVYLESLV ILASIPAGLL
60 70 80 90 100
IGSLLGLLLY LLTRCCDRRQ RKPSAQRCQS CSLVIITLMT CAAIGLGLYG
110 120 130 140 150
NDDFHNGLLQ AFGSGKSVEG LVLTLKRQTE SIKHDLETRM AGHKVEQLVE
160 170 180 190 200
KPHYNQTVVM LLIETSRLVT ENTSRAVASL DSMVHYFMKA KGSENDTSLM
210 220 230 240 250
GLLQLGEFYE SIRWPATLAF LTVLLLLCTV LVIGVARRSR CTLIFFSVSG
260 270 280 290 300
LFCIIICWLL AGVYLASSVA AGDFCMRPHD YMCRQVGMRS PYVDFLNCGT
310 320 330 340 350
PRNRFILRLN ESRDLVDRAR ESVEHMQRMS QETYPHIDIQ RTLNAMDNDL
360 370 380 390 400
EITLRNLTTL SATLDRRTID MHYEEALRGL CGGGLLGLSL MMVAGLLTSF
410 420 430 440 450
LLTILVYADS HAWIYLTKRP TLDADKSETA PLFPASNAPS ASISPTAPLS
460 470 480 490 500
TGTINRTLLH HQQASSGGGS GTLPGSGGGA GAGGGVGANG HNGVGPYRNG
510 520 530 540 550
SAGLRQGLAS PSSQSSHTSS TATYNNGTTS YHNSHQQHNN HLSGHHTLGR
560 570 580
LPSHHQQSAT YLPGPNNGKY ATLSKQCKTL ESNDFY
Length:586
Mass (Da):63,958
Last modified:June 26, 2013 - v1
Checksum:iA7911C018088A68B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AGB94970.1.
RefSeqiNP_001259124.1. NM_001272195.1.
UniGeneiDm.12259.

Genome annotation databases

EnsemblMetazoaiFBtr0330207; FBpp0303240; FBgn0261444.
GeneIDi31071.

Similar proteinsi

Entry informationi

Entry nameiM9PGE0_DROME
AccessioniPrimary (citable) accession number: M9PGE0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: November 22, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported