HLA-DR15

Functionⁱ

GO - Biological processⁱ

antigen processing and presentation Source: InterPro
immune response Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MHC class II antigenImported
Gene namesⁱ	Name:HLA-DR15Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Subcellular locationⁱ

GO - Cellular component

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	M9P8M8.
SMRⁱ	M9P8M8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	8 – 82	MHC_II_betaInterPro annotationAdd BLAST		75

Phylogenomic databases

eggNOGⁱ	ENOG410IWG3. Eukaryota. ENOG410YI0S. LUCA.

eggNOGⁱ

ENOG410IWG3. Eukaryota.
ENOG410YI0S. LUCA.

Family and domain databases

Gene3Dⁱ	3.10.320.10. 1 hit.
InterProⁱ	View protein in InterPro IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00969. MHC_II_beta. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000328. MHC_II_b_N. 1 hit.
SMARTⁱ	View protein in SMART SM00921. MHC_II_beta. 1 hit.
SUPFAMⁱ	SSF54452. SSF54452. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

M9P8M8-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
RFLWQPKREC HFFNGTERVR FLDRYFYNQE ESVRFDSDVG EFRAVTELGR 
        60         70         80 
PDAEYWNSQK DILEQARAAV DTYCRHNYGV VESFTVQRR

Length:89

Mass (Da):10,834

Last modified:June 26, 2013 - v1

Checksum:ⁱB0DADC7D8884DEA9

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1
Non-terminal residueⁱ	89	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	JQ824717 Genomic DNA. Translation: AFZ94258.1.
UniGeneⁱ	Hs.534322. Hs.696211. Hs.736560.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
M9P8M8	P01911 D7RIH8 X5DNQ0 B7VU65 Q06653 UPI0000110A9A Q8HWN3 A0A2D1BYB4 A0A2I4PZW1 A0A2H4G2R1 +105	Homo sapiens (Human)	266	UniRef100_P01911	Cluster: HLA class II histocompatibility antigen, DRB1-15 beta chain	116

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
M9P8M8	Q9GIY3 Q31646 Q6LBW7 H9C8X6 Q9TQ61 S0F2K8 S4T707 D7R0U4 F1C3G9 D7R0W0 +1198	Homo sapiens (Human) Colobus angolensis palliatus (Peters' Angolan colobus) Macaca mulatta (Rhesus macaque) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Macaca nemestrina (Pig-tailed macaque) Pan troglodytes troglodytes Pan troglodytes (Chimpanzee) Gorilla gorilla (western gorilla) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Pan troglodytes verus And more	266	UniRef90_Q9GIY3	Cluster: HLA class II histocompatibility antigen, DRB1-14 beta chain	1,209

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
M9P8M8	Q9GIY3 Q31646 Q6LBW7 H9C8X6 Q9TQ61 S0F2K8 S4T707 D7R0U4 F1C3G9 D7R0W0 +1618	Homo sapiens (Human) Colobus angolensis palliatus (Peters' Angolan colobus) Macaca mulatta (Rhesus macaque) Macaca nemestrina (Pig-tailed macaque) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Pan troglodytes verus Pan troglodytes (Chimpanzee) Pan troglodytes troglodytes Galago moholi (South African galago) (South African lesser bushbaby) Gorilla gorilla (western gorilla) And more	266	UniRef50_Q9GIY3	Cluster: HLA class II histocompatibility antigen, DRB1-14 beta chain	1,629

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	JQ824717 Genomic DNA. Translation: AFZ94258.1.
UniGeneⁱ	Hs.534322. Hs.696211. Hs.736560.

3D structure databases

ProteinModelPortalⁱ	M9P8M8.
SMRⁱ	M9P8M8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IWG3. Eukaryota. ENOG410YI0S. LUCA.

eggNOGⁱ

ENOG410IWG3. Eukaryota.
ENOG410YI0S. LUCA.

Family and domain databases

Gene3Dⁱ	3.10.320.10. 1 hit.
InterProⁱ	View protein in InterPro IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00969. MHC_II_beta. 1 hit.
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000328. MHC_II_b_N. 1 hit.
SMARTⁱ	View protein in SMART SM00921. MHC_II_beta. 1 hit.
SUPFAMⁱ	SSF54452. SSF54452. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	M9P8M8_HUMAN
Accessionⁱ	M9P8M8Primary (citable) accession number: M9P8M8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 26, 2013
	Last sequence update:	June 26, 2013
	Last modified:	January 31, 2018
	This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - M9P8M8 (M9P8M8_HUMAN)

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MHC class II antigen

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Plasma Membrane

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

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Annotation systems

Supporting data

UniProtKB - M9P8M8 (M9P8M8_HUMAN)

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MHC class II antigen

HLA-DR15

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ