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Protein
Submitted name:

Hyperkinetic, isoform I

Gene

Hk

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • potassium channel regulator activity Source: FlyBase
  • voltage-gated potassium channel activity Source: FlyBase

GO - Biological processi

  • circadian sleep/wake cycle, sleep Source: FlyBase
  • flight behavior Source: FlyBase
  • positive regulation of circadian sleep/wake cycle, sleep Source: FlyBase
  • potassium ion transport Source: FlyBase
  • protein oligomerization Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-1296072. Voltage gated Potassium channels.
R-DME-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Hyperkinetic, isoform IImported
Gene namesi
Name:HkImported
Synonyms:CG17779Imported, CG2287Imported, CG32688Imported, CG34319Imported, Dm_X:51771Imported, Dmel\CG43388Imported, hkImported, lincRNA.975Imported
ORF Names:CG43388Imported, Dmel_CG43388Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0263220. Hk.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiM9NGY7.
PRIDEiM9NGY7.

Expressioni

Gene expression databases

BgeeiFBgn0263220.
ExpressionAtlasiM9NGY7. differential.

Structurei

3D structure databases

ProteinModelPortaliM9NGY7.
SMRiM9NGY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 377Aldo_ket_redInterPro annotationAdd BLAST316

Phylogenomic databases

eggNOGiKOG1575. Eukaryota.
COG0667. LUCA.
GeneTreeiENSGT00550000074567.
OrthoDBiEOG091G0KDN.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiView protein in InterPro
IPR005983. K_chnl_volt-dep_bsu_KCNAB.
IPR005399. K_chnl_volt-dep_bsu_KCNAB-rel.
IPR023210. NADP_OxRdtase_dom.
IPR036812. NADP_OxRdtase_dom_sf.
PfamiView protein in Pfam
PF00248. Aldo_ket_red. 1 hit.
PRINTSiPR01577. KCNABCHANNEL.
SUPFAMiSSF51430. SSF51430. 1 hit.
TIGRFAMsiTIGR01293. Kv_beta. 1 hit.

Sequencei

Sequence statusi: Complete.

M9NGY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCRAPIASLD CMEEFSGTGG HLDFGRSISL GSNPALPLRH GSTPTPGLRY
60 70 80 90 100
KNLGKSGLRI SNVGLGTWPV FSPGVSDDQA EAILKLAIES GINLFDISEA
110 120 130 140 150
HSETEIGKIL QRAGWKRTAY VITTKVYWST KSEERGLSRK HIIECVRASL
160 170 180 190 200
QRLQLQYIDI VIIHKADPMC PMEEVVRAMS YVIQQGWAMY WGTARWSQVE
210 220 230 240 250
IMEAYTNCRQ FNCITPIVEQ SEYHMFCREK CELYLPEMYN KIGVGLMAWG
260 270 280 290 300
PLSMALSDTQ NGDKLFLPKG SFKTKSFSWT EDEINRNAAL SPQGSWGKDR
310 320 330 340 350
IDEGRRHCDR LRDLAALAEK LGCSPTQLSI AWSLKHEPVQ CLLLGATSAE
360 370 380 390
QLHQSLQSLQ LLPRLSSSVM LELERILENK PVRPPMISTL ALR
Length:393
Mass (Da):44,089
Last modified:June 26, 2013 - v1
Checksum:iB44C08D6BD9C1A7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AFH07326.1.
RefSeqiNP_001245612.1. NM_001258683.2.
UniGeneiDm.4020.

Genome annotation databases

EnsemblMetazoaiFBtr0307881; FBpp0300315; FBgn0263220.
GeneIDi31955.

Similar proteinsi

Entry informationi

Entry nameiM9NGY7_DROME
AccessioniPrimary (citable) accession number: M9NGY7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2013
Last sequence update: June 26, 2013
Last modified: November 22, 2017
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported