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M4XVY6 (M4XVY6_PASHA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 9. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. SAAS SAAS020634 RuleBase RU000544 HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. SAAS SAAS020633 HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity SAAS SAAS020633 HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding87 – 904ATP By similarity HAMAP-Rule MF_00124

Sites

Active site881Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1821Zinc By similarity HAMAP-Rule MF_00124
Metal binding1851Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
M4XVY6 [UniParc].

Last modified May 29, 2013. Version 1.
Checksum: EC4EF4BD670FC89E

FASTA19321,906
        10         20         30         40         50         60 
MAKLYFYYSS MNAGKSTTLL QSSYNYQERG MNTLVYTAAI DDRFGVGKVN SRIGISQEAN 

        70         80         90        100        110        120 
LFTADTNLFA EIKALHSNKA LHCILIDEAQ FLTKTQVYQL SDVVDKLKIP VLCYGLRTDF 

       130        140        150        160        170        180 
QAELFEGSKY LLAWADELEE LKTICDCGKK AHFVVRLNEK GEAIKDGEQI QIGGNDRYLS 

       190 
VCRYHYKQKL GKL 

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References

[1]"Complete Closed Genome Sequences of Mannheimia haemolytica Serotypes A1 and A6, Isolated from Cattle."
Harhay G.P., Koren S., Phillippy A.M., McVey D.S., Kuszak J., Clawson M.L., Harhay D.M., Heaton M.P., Chitko-McKown C.G., Smith T.P.
Genome Announc. 1:E00188-13(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: USDA-ARS-USMARC-185 EMBL AGI35284.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP004753 Genomic DNA. Translation: AGI35284.1.
RefSeqYP_007668792.1. NC_020834.1.

3D structure databases

ProteinModelPortalM4XVY6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAGI35284; AGI35284; D648_12800.
GeneID15007825.
KEGGmht:D648_12800.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameM4XVY6_PASHA
AccessionPrimary (citable) accession number: M4XVY6
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: April 16, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)