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Protein
Submitted name:

PARK2 splice variant

Gene

PARK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ubiquitin-protein transferase activity Source: Ensembl

GO - Biological processi

  1. adult locomotory behavior Source: Ensembl
  2. cellular protein catabolic process Source: Ensembl
  3. cellular response to toxic substance Source: Ensembl
  4. dopamine metabolic process Source: Ensembl
  5. dopamine uptake involved in synaptic transmission Source: Ensembl
  6. learning Source: Ensembl
  7. negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway Source: Ensembl
  8. norepinephrine metabolic process Source: Ensembl
  9. positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway Source: Ensembl
  10. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  11. positive regulation of protein linear polyubiquitination Source: Ensembl
  12. protein localization to mitochondrion Source: Ensembl
  13. regulation of neurotransmitter secretion Source: Ensembl
  14. response to endoplasmic reticulum stress Source: Ensembl
  15. startle response Source: Ensembl
  16. synaptic transmission, glutamatergic Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PARK2 splice variantImported
Gene namesi
Name:PARK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. neuron projection Source: Ensembl
  2. nucleus Source: Ensembl
  3. protein complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiM4T2U2. baseline and differential.

Sequencei

Sequence statusi: Complete.

M4T2U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30 
MHMKCPQPQC RLEWCWNCGC EWNRVCMGDH WFDV
Length:34
Mass (Da):4,230
Last modified:May 29, 2013 - v1
Checksum:iD72F6133ABFC8592
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC357594 mRNA. Translation: AGH62056.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC357594 mRNA. Translation: AGH62056.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

ExpressionAtlasiM4T2U2. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "PARK2 alternative splice variant."
    D'Agata V., La Cognata V., Iemmolo R., Cavallaro S.
    Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Substantia nigraImported.

Entry informationi

Entry nameiM4T2U2_HUMAN
AccessioniPrimary (citable) accession number: M4T2U2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: March 4, 2015
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.