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Protein

Undecaprenyl-diphosphatase

Gene

uppP

Organism
Lactobacillus plantarum ZJ316
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.UniRule annotation

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processAntibiotic resistanceUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphataseUniRule annotation (EC:3.6.1.27UniRule annotation)
Alternative name(s):
Bacitracin resistance proteinUniRule annotation
Undecaprenyl pyrophosphate phosphataseUniRule annotation
Gene namesi
Name:uppPUniRule annotationImported
ORF Names:zj316_0045Imported
OrganismiLactobacillus plantarum ZJ316Imported
Taxonomic identifieri1284663 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000011825 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei46 – 64HelicalUniRule annotationAdd BLAST19
Transmembranei85 – 104HelicalUniRule annotationAdd BLAST20
Transmembranei110 – 131HelicalUniRule annotationAdd BLAST22
Transmembranei193 – 213HelicalUniRule annotationAdd BLAST21
Transmembranei219 – 245HelicalUniRule annotationAdd BLAST27
Transmembranei257 – 274HelicalUniRule annotationAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Structurei

3D structure databases

SMRiM4KJQ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

KOiK06153.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase. 1 hit.
InterProiView protein in InterPro
IPR003824. UppP.
PANTHERiPTHR30622. PTHR30622. 1 hit.
PfamiView protein in Pfam
PF02673. BacA. 1 hit.
TIGRFAMsiTIGR00753. undec_PP_bacA. 1 hit.

Sequencei

Sequence statusi: Complete.

M4KJQ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDIFKAVIL GIVEGITEFL PISSTGHLVL VDEFIKMQQS TQFTDMFNVV
60 70 80 90 100
IQLGAIMAVV VLYFHKLNPL SPRKDTTEKR NTWVLWSKVL LAVIPSVIVG
110 120 130 140 150
LPLNDWMDEH LMNWAVVSAT LIIYGVLFIV IENHNKRLTP RFANLQTLPY
160 170 180 190 200
TTALFIGCFQ LLSLIPGTSR SGATILGAIL IGTSRYVATE FSFFMAIPTM
210 220 230 240 250
FGASLLKLVK FFAHGGSLAG LQGAVLAVGV IVSFVVAYLS IRFLLDYIKK
260 270
NDFKAFGWYR IVLGVLVIGY FTLIH
Length:275
Mass (Da):30,552
Last modified:May 29, 2013 - v1
Checksum:iDCC524DD6CD57631
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004082 Genomic DNA. Translation: AGE37584.1.
RefSeqiWP_003645539.1. NC_020229.1.

Genome annotation databases

EnsemblBacteriaiAGE37584; AGE37584; zj316_0045.
KEGGilpt:zj316_0045.
PATRICifig|1284663.3.peg.44.

Similar proteinsi

Entry informationi

Entry nameiM4KJQ3_LACPN
AccessioniPrimary (citable) accession number: M4KJQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: September 27, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported