Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Sialidase A (Neuraminidase A)

Gene

HMPREF1038_01674

Organism
Streptococcus pneumoniae gamPNI0373
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase A (Neuraminidase A)Imported
Gene namesi
ORF Names:HMPREF1038_01674Imported
OrganismiStreptococcus pneumoniae gamPNI0373Imported
Taxonomic identifieri697283 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000011868: Chromosome

Subcellular locationi

Secretedcell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Family & Domainsi

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.

Sequencei

Sequence statusi: Complete.

M4HWF7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYFRNRDID IERISMNRSV QERKCRYSIR KLSVGAVSMI VGAVVFGTSP
60 70 80 90 100
VLAQEGASEQ PLANETQLSG ESSTLTDTEK SQPSSETELS GNKQEQERKD
110 120 130 140 150
KQEEKIPRDY YARDLENVET VIEKEDVETN ASNDQRVDLS SELDKLKKLE
160 170 180 190 200
NATVHMEFKP DAKAPAFYNL FSVSSATKKD EYFTMAVYNN TATLEGRGSD
210 220 230 240 250
GKQFYNNYND APLKVKPGQW NSVTFTVEKP TAELPNGRVR LYVNGVLSRT
260 270 280 290 300
SLKSGNFIKD MPDVTHVQIG ATKRANNTVW GSNLQIRNLT VYNRALTPEE
310 320 330 340 350
VQKRSQLFKR SDLEKKLPEG AALTEKTDIF ESGRNGKPNK DGIKSYRIPA
360 370 380 390 400
LLKTDKGTLI AGADERRLHS SDWGDIGMVI RRSEDNGKTW GDRVTITNLR
410 420 430 440 450
DNPKASDPSI GSPVNIDMVL VQDPETKRIF SIYDMFPEGK GIFGMSSQKE
460 470 480 490 500
EAYKEIDGKT YQILYREGEK GAYTIRENGT VYTPDGKATD YRVVVDPVKP
510 520 530 540 550
AYSDKGDLYK GDQLLGNIYF TTNKTSPFRI AKDSYLWMSY SDDDGKTWSA
560 570 580 590 600
PQDITPMVKA DWMKFLGVGP GTGIVLRNGP HKGRILIPVY TTNNVSHLNG
610 620 630 640 650
SQSSRVIYSD DHGKTWHAGE AVNDNRQVDG QKIHSSTMNN KRAQNTESTV
660 670 680 690 700
VQLNNGDVKL FMRGLTGDLQ VATSKDGGVT WEKDIKRYPQ VKDVYVQMSA
710 720 730 740 750
IHTMHNGKEY IILSNAGGPN RENGMVHLAR VEENGELTWL KHNPIQKGEF
760 770 780 790 800
AYNSLQELGN GEYGILYEHT EKGQNAYTLS FRKFNWDFLS KDLISPTEAK
810 820 830 840 850
VKRTREMGKG VIGLEFDSEV LVNKAPTLQL ANGKTATFLT QYDSKTLLFA
860 870 880 890 900
VDKEDIGQEI IGIAKGSIES MHNLPVNLAG ARVPGGVNGS KAAVHEVPEF
910 920 930 940 950
TGGVNGTEPA VHEIAEYKGS DSLVTLTTKE DYTYKAPLAQ QALPETGNKE
960 970
SDLLASLGLT AFFLGLFTLG KKREQ
Length:975
Mass (Da):108,499
Last modified:May 29, 2013 - v1
Checksum:i6595B71E80C25A58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001845 Genomic DNA. Translation: AFS43698.1.
RefSeqiYP_006743822.1. NC_018630.1.

Genome annotation databases

EnsemblBacteriaiAFS43698; AFS43698; HMPREF1038_01674.
GeneIDi13694985.
KEGGispng:HMPREF1038_01674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001845 Genomic DNA. Translation: AFS43698.1.
RefSeqiYP_006743822.1. NC_018630.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAFS43698; AFS43698; HMPREF1038_01674.
GeneIDi13694985.
KEGGispng:HMPREF1038_01674.

Phylogenomic databases

KOiK01186.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GamPNI0373Imported.

Entry informationi

Entry nameiM4HWF7_STREE
AccessioniPrimary (citable) accession number: M4HWF7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: January 7, 2015
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.