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M4HSQ4

- M4HSQ4_STREE

UniProt

M4HSQ4 - M4HSQ4_STREE

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, HMPREF1038_01112
Organism
Streptococcus pneumoniae gamPNI0373
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei561 – 5611 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:HMPREF1038_01112Imported
OrganismiStreptococcus pneumoniae gamPNI0373Imported
Taxonomic identifieri697283 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000011868: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M4HSQ4-1 [UniParc]FASTAAdd to Basket

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MSLQKLENYS NKSVVQEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST    50
QEDYQGLNRL VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN 100
IDQDYLGKLS TTIKLVAEKE NAVEILEHLN VVPVLTAHPT QVQRKSMLDL 150
TNHIHSLLRK YRDVKLGLIN KDKWYNDLRR YIEIIMQTDM IREKKLKVTN 200
EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP ITMGMWIGGD 250
RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 300
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET 350
ANDFYKDLIA IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD 400
SSVYEACVAE LLKSAGIHSR YSELSEEEKC DLLLKELEED PRILSATHAE 450
KSELLAKELA IFKTARVLKD KLGDDVIRQT IISHATNLSD MLELAILLKE 500
VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK KWIDSRNNYQ 550
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 600
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV 650
SAAINRMITQ KKSDTNTPNR YEAIMDQVVD RSYDIYRDLV FGNEHFYDYF 700
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY 750
GVGSSFKEFI NKNPENIAIL RDMYQNWPFF QSLLSNVDMV LSKSNMNIAF 800
EYAKLCEDEQ VKAIYEIILN EWQVTKNVIL AIEGHDELLA DNPYLKASLD 850
YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG 898
Length:898
Mass (Da):103,324
Last modified:May 29, 2013 - v1
Checksum:i6353A9CA9CCACFFD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001845 Genomic DNA. Translation: AFS43162.1.
RefSeqiYP_006743286.1. NC_018630.1.

Genome annotation databases

EnsemblBacteriaiAFS43162; AFS43162; HMPREF1038_01112.
GeneIDi13694404.
KEGGispng:HMPREF1038_01112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001845 Genomic DNA. Translation: AFS43162.1 .
RefSeqi YP_006743286.1. NC_018630.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFS43162 ; AFS43162 ; HMPREF1038_01112 .
GeneIDi 13694404.
KEGGi spng:HMPREF1038_01112.

Phylogenomic databases

KOi K01595.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GamPNI0373Imported.

Entry informationi

Entry nameiM4HSQ4_STREE
AccessioniPrimary (citable) accession number: M4HSQ4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2013
Last sequence update: May 29, 2013
Last modified: June 11, 2014
This is version 9 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi