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Protein
Submitted name:

Dopamine receptor D2a

Gene
N/A
Organism
Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine receptor D2aImported
OrganismiXiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)Imported
Taxonomic identifieri8083 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaeXiphophorus
Proteomesi
  • UP000002852 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 57HelicalSequence analysisAdd BLAST24
Transmembranei69 – 91HelicalSequence analysisAdd BLAST23
Transmembranei107 – 129HelicalSequence analysisAdd BLAST23
Transmembranei150 – 170HelicalSequence analysisAdd BLAST21
Transmembranei190 – 217HelicalSequence analysisAdd BLAST28
Transmembranei394 – 414HelicalSequence analysisAdd BLAST21
Transmembranei434 – 453HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi8083.ENSXMAP00000008963.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 450G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST402

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00890000139331.
InParanoidiM4A3B9.
OMAiRNWSRPF.
OrthoDBiEOG091G06VI.

Family and domain databases

InterProiView protein in InterPro
IPR001922. Dopamine_D2_rcpt.
IPR000929. Dopamine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00567. DOPAMINED2R.
PR00242. DOPAMINER.
PR00237. GPCRRHODOPSN.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

M4A3B9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFGQYAYN DSFNDNGTWH FNETEQEQRH PYNYYAMLLT LLIFVIVFGN
60 70 80 90 100
VLVCMAVSRE KALQTTTNYL IVSLAVADLL VATLVMPWVV YLEVVGEWRF
110 120 130 140 150
SKIHCDIFVT LDVMMCTASI LNLCAISIDR YTAVAMPMLY NTRYSSRRRV
160 170 180 190 200
TVMISVVWVL SFAISCPLLF GLNNTATRDA SLCVIANPAF VVYSSIVSFY
210 220 230 240 250
VPFIITLLVY VQIYVVLRKR RKRVNTKPKR RVCQPADTDV ATSLRDKCTH
260 270 280 290 300
PEDVRLCTMI VKSNGSLPAN KKRVIFIKEA ATDGDDLELD ELNNSGSSHR
310 320 330 340 350
QRHQTHSALG DTPATSHQQL MPNKANASPT STPPTPPEDG HKAEKNGEPK
360 370 380 390 400
EALADPAPVV AKAFQTQALP NGKTQTSVKN MSKRKISQQK EKKATQMLAI
410 420 430 440 450
VLGVFIICWL PFFITHILNT HCTKCKVPAE MYNAFTWLGY VNSAVNPIIY
460
TTFNIEFRKA FIKILHC
Length:467
Mass (Da):52,598
Last modified:May 1, 2013 - v1
Checksum:iCB4F4C2ED218D9F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGAJ01010637 Genomic DNA. No translation available.
AGAJ01010638 Genomic DNA. No translation available.
AGAJ01010639 Genomic DNA. No translation available.
RefSeqiXP_005801112.1. XM_005801055.1.

Genome annotation databases

EnsembliENSXMAT00000008977; ENSXMAP00000008963; ENSXMAG00000008934.
GeneIDi102228885.

Similar proteinsi

Entry informationi

Entry nameiM4A3B9_XIPMA
AccessioniPrimary (citable) accession number: M4A3B9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: October 25, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported