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Protein
Submitted name:

Aquaporin 2

Gene

AQP2

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aquaporin 2Imported
Gene namesi
Name:AQP2Imported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei44 – 63HelicalSequence analysisAdd BLAST20
Transmembranei90 – 111HelicalSequence analysisAdd BLAST22
Transmembranei131 – 153HelicalSequence analysisAdd BLAST23
Transmembranei165 – 184HelicalSequence analysisAdd BLAST20
Transmembranei206 – 228HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000014416.

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0223. Eukaryota.
COG0580. LUCA.
GeneTreeiENSGT00760000119223.
InParanoidiM3YSV6.
OMAiLLGIHYT.
OrthoDBiEOG091G166T.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiView protein in InterPro
IPR023271. Aquaporin-like.
IPR034294. Aquaporin_transptr.
IPR000425. MIP.
IPR022357. MIP_CS.
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiView protein in Pfam
PF00230. MIP. 1 hit.
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiView protein in PROSITE
PS00221. MIP. 1 hit.

Sequencei

Sequence statusi: Complete.

M3YSV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PAHSMWELRS IAFSRAVFAE FLATLLFVFF GLGSALNWPQ ALPSVLQIAM
60 70 80 90 100
AFGLGIGTLV QALGHISGAH INPAVTVACL VGCHVSFLRA AFYVAAQLLG
110 120 130 140 150
AVAGAALLHE ITPPDIRGDL AVNALSNNTT AGQAVTVELF LTLQLVLCIF
160 170 180 190 200
ASTDERRGDN LGTPALSIGF SVALGHLLGI HYTGCSMNPA RSLAPAVVTG
210 220 230 240 250
KFDDHWVFWI GPLVGAVLGS LLYNYVLFPP AKSLAERLAV LKGQEPDADW
260 270
EEREVRRRQS VELHSPQSPP RGSKA
Length:275
Mass (Da):29,258
Last modified:May 1, 2013 - v1
Checksum:i3914499F034B0FAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01095544 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMPUT00000014648; ENSMPUP00000014416; ENSMPUG00000014526.

Similar proteinsi

Entry informationi

Entry nameiM3YSV6_MUSPF
AccessioniPrimary (citable) accession number: M3YSV6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: March 28, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported