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Protein

Transmembrane channel-like protein

Gene

TMC6

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane channel-like proteinUniRule annotation
Gene namesi
Name:TMC6Imported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei290 – 310HelicalUniRule annotationAdd BLAST21
Transmembranei380 – 402HelicalUniRule annotationAdd BLAST23
Transmembranei422 – 443HelicalUniRule annotationAdd BLAST22
Transmembranei455 – 478HelicalUniRule annotationAdd BLAST24
Transmembranei599 – 622HelicalUniRule annotationAdd BLAST24
Transmembranei672 – 689HelicalUniRule annotationAdd BLAST18

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000013240.

Family & Domainsi

Sequence similaritiesi

Belongs to the TMC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG410IH09. Eukaryota.
ENOG410XR0Y. LUCA.
GeneTreeiENSGT00760000119171.
InParanoidiM3YPI2.
OMAiNIQESEW.
OrthoDBiEOG091G04K4.

Family and domain databases

InterProiView protein in InterPro
IPR012496. TMC.
PfamiView protein in Pfam
PF07810. TMC. 1 hit.

Sequencei

Sequence statusi: Complete.

M3YPI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQPLNFVLH VPETPEDHGQ EPSPYDESDV HDSFHQLIQE QSRWVAEEGL
60 70 80 90 100
ELQERERGAG APQTTGSGSR IPPGPEDAGA PSTATLRILA SMPSRTIGRS
110 120 130 140 150
RGAIISQYYN RTVQLRRRVS RPELRGVGRS ARPSLRLYDL ELDPAALEEE
160 170 180 190 200
EKRLLLVKEL QGLTVAQRDH MLRGMPLGLA EKRCLRSVPV GLGRLQTHCR
210 220 230 240 250
GGGGLGGGYP LGGVRSIPGP TLMPPVSPER RAGPQGGSGG AGLAGVGSSP
260 270 280 290 300
AVAGSETPAS CNSSLTRPCA LPPGGPCGRE AESLPYNMPL AYLFTVGVAF
310 320 330 340 350
FITCITLVYS MSRSFGESYR VGSASGVHAV TVFCSWDHKV TQRRASRLQC
360 370 380 390 400
DNIRTHLKEL LAERQRRQGP RSACGRLRHV AVLGLVWLLC LGTTVGCTMA
410 420 430 440 450
VYAFSELMIK SPVSADQEGA LLALPVVVCL LNLGAPYLFR CLAALERQDS
460 470 480 490 500
PVLEVYLAIC RNLIFKMAIL GILCYHWLGR RVGTLKDQCW ENFVGQELYR
510 520 530 540 550
LTVLDFIFVL LDTLFGELVW RLISEKKLKR REKPEFDIAG NVLELIYGQT
560 570 580 590 600
LTWLGVLFCP LLPAVQIIKL LLIFYVKKTS LMANCQAPRR PWLASHMSTV
610 620 630 640 650
FVSLLCFPSF LGAAVFLCYA VWQVKPSSTC GPFRTLDTMY EAGKVWVRRL
660 670 680 690 700
EAAGPRVSWL PWVHRYLVEN TFPIYLVSAL LLAVIYLNIQ VVKGQRRVIC
710 720 730 740
LLKEQISNEG EDKVFLINRL HSVYERKERS RAGRSQETER LVDHPDAW
Length:748
Mass (Da):82,908
Last modified:May 1, 2013 - v1
Checksum:i48094F49FEA9680E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01025197 Genomic DNA. No translation available.
AEYP01025198 Genomic DNA. No translation available.
AEYP01025199 Genomic DNA. No translation available.
AEYP01025200 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMPUT00000013452; ENSMPUP00000013240; ENSMPUG00000013339.

Similar proteinsi

Entry informationi

Entry nameiM3YPI2_MUSPF
AccessioniPrimary (citable) accession number: M3YPI2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: June 7, 2017
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported