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Protein

V-type proton ATPase subunit H

Gene

ATP6V1H

Organism
Mustela putorius furo (European domestic ferret) (Mustela furo)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit HUniRule annotation
Gene namesi
Name:ATP6V1HImported
OrganismiMustela putorius furo (European domestic ferret) (Mustela furo)Imported
Taxonomic identifieri9669 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeMustelinaeMustela
Proteomesi
  • UP000000715 Componenti: Unassembled WGS sequence

Subcellular locationi

Interactioni

Subunit structurei

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.UniRule annotation

Protein-protein interaction databases

STRINGi9669.ENSMPUP00000010568.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini349 – 464V-ATPase_H_CInterPro annotationAdd BLAST116

Sequence similaritiesi

Belongs to the V-ATPase H subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2759. Eukaryota.
COG5231. LUCA.
GeneTreeiENSGT00390000003289.
InParanoidiM3YGW1.
OMAiRPIPWDG.
OrthoDBiEOG091G0NQW.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
1.25.40.150. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR004908. ATPase_V1-cplx_hsu.
IPR011987. ATPase_V1-cplx_hsu_C.
IPR038497. ATPase_V1-cplx_hsu_C_sf.
PANTHERiPTHR10698. PTHR10698. 1 hit.
PfamiView protein in Pfam
PF11698. V-ATPase_H_C. 1 hit.
PIRSFiPIRSF032184. ATPase_V1_H. 1 hit.
SUPFAMiSSF48371. SSF48371. 1 hit.

Sequencei

Sequence statusi: Complete.

M3YGW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKMDIRGAV DAAVPTNIIA AKAAEVRANK VNWQSYLQGQ MISAEDCEFI
60 70 80 90 100
QRFEMKRSPE EKQEMLQTEG SQCAKTFINL MTHISKEQTV QYILTMVDDM
110 120 130 140 150
LQENHQRVSI FFDYAKRSKN TAWSYFLPML NRQDLFTVHM AARIIAKLAA
160 170 180 190 200
WGKELMEGSD LNYYFNWIKT QLSSQKLRGS GVAVETGTVS SSDSSQYVQC
210 220 230 240 250
VAGCLQLMLR VNEYRFAWVE ADGVNCIMGV LSNKCGFQLQ YQMIFSIWLL
260 270 280 290 300
AFSPQMCEHL RRYNIIPVLS DILQESVKEK VTRIILAAFR NFLEKSTERE
310 320 330 340 350
TRQEYALAMI QCKVLKQLEN LEQQKYDDED ISEDIKFLLE KLGESVQDLS
360 370 380 390 400
SFDEYSSELK SGRLEWSPVH KSEKFWRENA VRLNEKNYEL LKILTKLLEV
410 420 430 440 450
SDDPQVLAVA AHDVGEYVRH YPRGKRVIEQ LGGKQLVMNH MHHEDQQVRY
460 470 480
NALLAVQKLM VHNWEYLGKQ LQSEQPQTAA ARS
Length:483
Mass (Da):55,898
Last modified:May 1, 2013 - v1
Checksum:i21CE24AE26C23E07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYP01070908 Genomic DNA. No translation available.
AEYP01070909 Genomic DNA. No translation available.
AEYP01070910 Genomic DNA. No translation available.
AEYP01070911 Genomic DNA. No translation available.
AEYP01070912 Genomic DNA. No translation available.
AEYP01070913 Genomic DNA. No translation available.
AEYP01070914 Genomic DNA. No translation available.
RefSeqiXP_004768878.1. XM_004768821.2.
XP_004768879.1. XM_004768822.2.

Genome annotation databases

EnsembliENSMPUT00000010738; ENSMPUP00000010568; ENSMPUG00000010647.
GeneIDi101686046.

Similar proteinsi

Entry informationi

Entry nameiM3YGW1_MUSPF
AccessioniPrimary (citable) accession number: M3YGW1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: March 28, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported