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Protein
Submitted name:

Glutamate ionotropic receptor NMDA type subunit 2B

Gene

GRIN2B

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate ionotropic receptor NMDA type subunit 2BImported
Gene namesi
Name:GRIN2BImported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome B4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 39HelicalSequence analysisAdd BLAST20
Transmembranei499 – 521HelicalSequence analysisAdd BLAST23
Transmembranei541 – 559HelicalSequence analysisAdd BLAST19
Transmembranei571 – 596HelicalSequence analysisAdd BLAST26
Transmembranei762 – 783HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

Expressioni

Gene expression databases

BgeeiENSFCAG00000013189

Interactioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000012231

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini372 – 740PBPeInterPro annotationAdd BLAST369
Domaini381 – 444Lig_chan-Glu_bdInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1053 Eukaryota
ENOG410XNUR LUCA
GeneTreeiENSGT00910000143978
InParanoidiM3WID6
KOiK05210
OMAiRNNYPEM
OrthoDBiEOG091G09KH

Family and domain databases

InterProiView protein in InterPro
IPR001828 ANF_lig-bd_rcpt
IPR019594 Glu/Gly-bd
IPR001508 Iono_rcpt_met
IPR001320 Iontro_rcpt
IPR018884 NMDAR2_C
IPR028082 Peripla_BP_I
PfamiView protein in Pfam
PF01094 ANF_receptor, 1 hit
PF00060 Lig_chan, 1 hit
PF10613 Lig_chan-Glu_bd, 1 hit
PF10565 NMDAR2_C, 1 hit
PRINTSiPR00177 NMDARECEPTOR
SMARTiView protein in SMART
SM00918 Lig_chan-Glu_bd, 1 hit
SM00079 PBPe, 1 hit
SUPFAMiSSF53822 SSF53822, 1 hit

Sequencei

Sequence statusi: Complete.

M3WID6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGSLIIEWV ELLCLQLGSL LSLAYTFYFI LIFFKFIYFE RGGWHGKKKR
60 70 80 90 100
ERIPSRLHTD SKEPTVVLDP MNCETMTWDE SSMFFQFGPS IEQQASVMLN
110 120 130 140 150
IMEEYDWYIF SIVTTYFPGY QDFVNKIRST IENSFVGWEL EEVLLLDMSL
160 170 180 190 200
DDGDSKIQNQ LKKLQSPIIL LYCTKEEATY IFEVANSVGL TGYGYTWIVP
210 220 230 240 250
SLVAGDTDTV PSEFPTGLIS VSYDEWDYGL PARVRDGIAI ITTAASDMLS
260 270 280 290 300
EHSFIPEPKS SCYNTHEKRI YQSNMLNRYL INVTFEGRNL SFSEDGYQMH
310 320 330 340 350
PKLVIILLNK ERKWERVGKW KDKSLQMKYY VWPRMCPETE EQEDDHLSIV
360 370 380 390 400
TLEEAPFVIV ESVDPLSGTC MRNTVPCQKR IVSENKTDEE PGYIKKCCKG
410 420 430 440 450
FCIDILKKIS KSVKFTYDLY LVTNGKHGKK INGTWNGMIG EVVMKRAYMA
460 470 480 490 500
VGSLTINEER SEVVDFSVPF IETGISVMVS RSNGTVSPSA FLEPFSADVW
510 520 530 540 550
VMMFVMLLIV SAVAVFVFEY FSPVGYNRCL ADGREPGGPS FTIGKAIWLL
560 570 580 590 600
WGLVFNNSVP VQNPKGTTSK IMVSVWAFFA VIFLASYTAN LAAFMIQEEY
610 620 630 640 650
VDQVSGLSDK KFQRPNDFSP PFRFGTVPNG STERNIRNNY AEMHAYMGKF
660 670 680 690 700
NQRGVDDALL SLKTGKLDAF IYDAAVLNYM AGRDEGCKLV TIGSGKVFAS
710 720 730 740 750
TGYGIAIQKD SGWKRQVDLA ILQLFGDGEM EELEALWLTG ICHNEKNEVM
760 770 780 790 800
SSQLDIDNMA GVFYMLGAAM ALSLITFICE HLFYWQFRHC FMGVCSGKPG
810 820 830 840 850
MVFSISRGIY SCIHGVAIEE RQSVMNSPTA TMNNTHSNIL RLLRTAKNMA
860 870 880 890 900
NLSGVNGSPQ SALDFIRRES SVYDISEHRR SFTHSDCKSY NNPPCEENLF
910 920 930 940 950
SDYISEVERT FGNLQLKDSN VYQDHYHHHH RPHSIGSASS IDGLYDCDNP
960 970 980 990 1000
PFTTQPRSIS KKPLDIGLPS SKHSQLSDLY GKFSFKSDRY SGHDDLIRSD
1010 1020 1030 1040 1050
VSDISTHTVT YGNIEGNAAK RRKQQYKDSL KKRPASAKSR REFDEIELAY
1060 1070 1080 1090 1100
RRRPPRSPDH KRYFRDKEGL RDFYLDQFRT KENSPHWEHV DLTDIYKEQG
1110 1120 1130 1140 1150
DDFKRDSVSG GGPCTNRSHL KHGAGDKHGV VSGVPAPWEK NLANVDWEDR
1160 1170 1180 1190 1200
SGGGNFCRSC PSKLHNYSAS VAGQNSGRQA CIRCEACKKA GNLYDISEDN
1210 1220 1230 1240 1250
SLQELDQPAA PVAVTSSAST TKYPQSPTNS KAQKKTRNKL RRQHSYDTFV
1260 1270 1280 1290 1300
DLQKEEAALA PRSVSLKDKG RFLDGSPYAH MFEMPAGEST FANNKSSVPT
1310 1320 1330 1340 1350
AGHHHHHNNP GGGYMLSKSL YPDRVTQNPF IPTFGDDQCL LHGSKSYFFR
1360 1370 1380 1390 1400
QPTVAGAPKA RPDFRALVTN KPVVSALHGA VPGRFQKDIC IGNQSNPCVP
1410 1420
NNKNPRAFNG SSNGHVYEKL SSIESDV
Length:1,427
Mass (Da):160,790
Last modified:February 28, 2018 - v2
Checksum:i24BBD0EA7D4595BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG03332876 Genomic DNA No translation available.
AANG03332877 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSFCAT00000013192; ENSFCAP00000012231; ENSFCAG00000013189
KEGGifca:101094356

Similar proteinsi

Entry informationi

Entry nameiM3WID6_FELCA
AccessioniPrimary (citable) accession number: M3WID6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: February 28, 2018
Last modified: March 28, 2018
This is version 44 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported