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Protein
Submitted name:

Uncharacterized protein

Gene

PCSK1

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: Ensembl

GO - Biological processi

  1. peptide biosynthetic process Source: Ensembl
  2. peptide hormone processing Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PCSK1Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
ProteomesiUP000011712 Componenti: Chromosome A1

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation
Contains peptidase S8 domain.SAAS annotation
Contains peptidase Sdomain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00750000117358.
InParanoidiM3W5Q0.
KOiK01359.
OMAiNNPGWKK.
OrthoDBiEOG7BW0JD.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR022005. Proho_convert.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF12177. Proho_convert. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M3W5Q0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERRAWTLQC TAFALFCAWY ALNSVKAKRQ FVNEWAAEIP GGPEAASAIA
60 70 80 90 100
EELGYDLLGQ IGSLENHYLF KHKNHPRRSR RSAFHITKRL SDDDRVIWAE
110 120 130 140 150
QQYEKERSKR SVLRDSALNL FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP
160 170 180 190 200
VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY
210 220 230 240 250
DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE
260 270 280 290 300
ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEF GVKQGRQGKG
310 320 330 340 350
SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST
360 370 380 390 400
LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP
410 420 430 440 450
NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV
460 470 480 490 500
DLADPRTWTS VPEKKECVVK DNEFEPRALK GNGEVIIEIP TRACEEQENA
510 520 530 540 550
IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN
560 570 580 590 600
WDFMSVHTWG ENPIGTWTLR ITDMSGRMQN EGRIVNWKLI FHGTSSQPEH
610 620 630 640 650
MKQPRVYTSY NTVQNDRRGV EKMVDLGEEQ PTQENPKKNP LMSKSPSGDS
660 670 680 690 700
TGDRRNELAE AAPSEAMLRL LQSAFNKNSP PKQSPKKPPS AKLNIPYETF
710 720 730 740 750
YEALEKLNKP SQLKESEDSL YNDYVDVFYN TKPYKHRDDR LLQALVDILR

EEN
Length:753
Mass (Da):84,460
Last modified:April 30, 2013 - v1
Checksum:i7D53EF813AB1BF56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG02175695 Genomic DNA. No translation available.
AANG02175696 Genomic DNA. No translation available.
AANG02175697 Genomic DNA. No translation available.
RefSeqiXP_003981208.1. XM_003981159.3.

Genome annotation databases

EnsembliENSFCAT00000006332; ENSFCAP00000005882; ENSFCAG00000006327.
GeneIDi101082627.
KEGGifca:101082627.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG02175695 Genomic DNA. No translation available.
AANG02175696 Genomic DNA. No translation available.
AANG02175697 Genomic DNA. No translation available.
RefSeqiXP_003981208.1. XM_003981159.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000006332; ENSFCAP00000005882; ENSFCAG00000006327.
GeneIDi101082627.
KEGGifca:101082627.

Organism-specific databases

CTDi5122.

Phylogenomic databases

GeneTreeiENSGT00750000117358.
InParanoidiM3W5Q0.
KOiK01359.
OMAiNNPGWKK.
OrthoDBiEOG7BW0JD.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR022005. Proho_convert.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF12177. Proho_convert. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  2. "Sequence assembly of the Felis catus genome version 6.2."
    Hillier L.W., Warren W., Obrien S., Wilson R.K.
    Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  3. Ensembl
    Submitted (FEB-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: breed AbyssinianImported.

Entry informationi

Entry nameiM3W5Q0_FELCA
AccessioniPrimary (citable) accession number: M3W5Q0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 30, 2013
Last sequence update: April 30, 2013
Last modified: March 31, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.