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M3W5Q0

- M3W5Q0_FELCA

UniProt

M3W5Q0 - M3W5Q0_FELCA

Protein
Submitted name:

Uncharacterized protein

Gene

PCSK1

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 11 (01 Oct 2014)
      Sequence version 1 (01 May 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase activity Source: Ensembl

    GO - Biological processi

    1. peptide biosynthetic process Source: Ensembl
    2. peptide hormone processing Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:PCSK1Imported
    OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
    Taxonomic identifieri9685 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
    ProteomesiUP000011712: Chromosome A1

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S8 family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117689.
    KOiK01359.
    OMAiNNPGWKK.
    OrthoDBiEOG7BW0JD.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProiIPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view]
    PANTHERiPTHR10795. PTHR10795. 1 hit.
    PfamiPF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view]
    PRINTSiPR00723. SUBTILISIN.
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    M3W5Q0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERRAWTLQC TAFALFCAWY ALNSVKAKRQ FVNEWAAEIP GGPEAASAIA    50
    EELGYDLLGQ IGSLENHYLF KHKNHPRRSR RSAFHITKRL SDDDRVIWAE 100
    QQYEKERSKR SVLRDSALNL FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP 150
    VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY 200
    DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE 250
    ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEF GVKQGRQGKG 300
    SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST 350
    LATSYSSGDY TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP 400
    NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV 450
    DLADPRTWTS VPEKKECVVK DNEFEPRALK GNGEVIIEIP TRACEEQENA 500
    IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE RDTSPNGFKN 550
    WDFMSVHTWG ENPIGTWTLR ITDMSGRMQN EGRIVNWKLI FHGTSSQPEH 600
    MKQPRVYTSY NTVQNDRRGV EKMVDLGEEQ PTQENPKKNP LMSKSPSGDS 650
    TGDRRNELAE AAPSEAMLRL LQSAFNKNSP PKQSPKKPPS AKLNIPYETF 700
    YEALEKLNKP SQLKESEDSL YNDYVDVFYN TKPYKHRDDR LLQALVDILR 750
    EEN 753
    Length:753
    Mass (Da):84,460
    Last modified:May 1, 2013 - v1
    Checksum:i7D53EF813AB1BF56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AANG02175695 Genomic DNA. No translation available.
    AANG02175696 Genomic DNA. No translation available.
    AANG02175697 Genomic DNA. No translation available.
    RefSeqiXP_003981208.1. XM_003981159.2.

    Genome annotation databases

    EnsembliENSFCAT00000006332; ENSFCAP00000005882; ENSFCAG00000006327.
    GeneIDi101082627.
    KEGGifca:101082627.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AANG02175695 Genomic DNA. No translation available.
    AANG02175696 Genomic DNA. No translation available.
    AANG02175697 Genomic DNA. No translation available.
    RefSeqi XP_003981208.1. XM_003981159.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSFCAT00000006332 ; ENSFCAP00000005882 ; ENSFCAG00000006327 .
    GeneIDi 101082627.
    KEGGi fca:101082627.

    Organism-specific databases

    CTDi 5122.

    Phylogenomic databases

    GeneTreei ENSGT00750000117689.
    KOi K01359.
    OMAi NNPGWKK.
    OrthoDBi EOG7BW0JD.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProi IPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view ]
    PANTHERi PTHR10795. PTHR10795. 1 hit.
    Pfami PF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view ]
    PRINTSi PR00723. SUBTILISIN.
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AbyssinianImported.
    2. "Sequence assembly of the Felis catus genome version 6.2."
      Hillier L.W., Warren W., Obrien S., Wilson R.K.
      Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AbyssinianImported.
    3. Ensembl
      Submitted (MAR-2013) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: breed AbyssinianImported.

    Entry informationi

    Entry nameiM3W5Q0_FELCA
    AccessioniPrimary (citable) accession number: M3W5Q0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2013
    Last sequence update: May 1, 2013
    Last modified: October 1, 2014
    This is version 11 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3