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M3W2W5

- M3W2W5_FELCA

UniProt

M3W2W5 - M3W2W5_FELCA

Protein
Submitted name:

Uncharacterized protein

Gene

TGM2

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (01 May 2013)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 calcium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei277 – 2771UniRule annotation
    Active sitei335 – 3351UniRule annotation
    Active sitei358 – 3581UniRule annotation
    Metal bindingi398 – 3981CalciumUniRule annotation
    Metal bindingi400 – 4001CalciumUniRule annotation
    Metal bindingi447 – 4471CalciumUniRule annotation
    Metal bindingi452 – 4521CalciumUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

    GO - Biological processi

    1. apoptotic cell clearance Source: Ensembl
    2. branching involved in salivary gland morphogenesis Source: Ensembl
    3. peptide cross-linking Source: InterPro
    4. positive regulation of cell adhesion Source: Ensembl
    5. salivary gland cavitation Source: Ensembl

    Keywords - Ligandi

    CalciumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:TGM2Imported
    OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
    Taxonomic identifieri9685 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
    ProteomesiUP000011712: Chromosome A3

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115156.
    KOiK05625.
    OMAiANGRDHH.
    OrthoDBiEOG7WT40M.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view]
    PANTHERiPTHR11590. PTHR11590. 1 hit.
    PfamiPF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
    SMARTiSM00460. TGc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    M3W2W5-1 [UniParc]FASTAAdd to Basket

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    MAEELVLERC DLELEANGRD HHTADLCREK LVVRRGQAFR LTLHFEGRNY    50
    EASVDRLTFS VTTGPAPSEE AGTRARFPLS DAVEEGAWTA EVVGQQDSAL 100
    SLQLSTPPNA PIGLYRLSLE ASTGYQGSSF VLGHFILLFN PWCPGDAVYL 150
    DSDEERHEYI LTQHGFIYQG LATFIKNIPW NFGQFEDGIL DICLTLLDMN 200
    PKFLRDAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGIS 250
    PMFWIGSVDI LRRWKSSGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN 300
    YNSAHDQNSN LLIEYFRNEF GEIQGDKSEM IWNFHCWVES WMSRPDLQPG 350
    YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD 400
    VVDWIRQDDG SMHKSINHSL VVGLKISTKS VGRDERQDIT HTYKYPEGSP 450
    EEREAFKRAN HLNKLTEKED TGMAMRIRVS QSMSMGSDFD VFAYITNNTS 500
    EEHTCRLLLC ARTVSYNGIL GPECGTKDLL NLSLAPFSEK SIPLRILYEK 550
    YCDCLTESNL IKVRGLLTEP AVNSYLLAER DIYLENPEIK IRILGEPKQK 600
    RKLVAEVSLR NPLTTPLSDC IFTVEGAGLT EEQKVVEIPD PVEAGEDAKV 650
    RVDLLPLHVG RHKLVVNFES DKLKAVKGFR NVIVGPA 687
    Length:687
    Mass (Da):77,162
    Last modified:May 1, 2013 - v1
    Checksum:i3E8AF10B929170CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AANG02187171 Genomic DNA. No translation available.
    RefSeqiXP_003983523.1. XM_003983474.2.

    Genome annotation databases

    EnsembliENSFCAT00000004809; ENSFCAP00000004444; ENSFCAG00000004808.
    GeneIDi101098215.
    KEGGifca:101098215.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AANG02187171 Genomic DNA. No translation available.
    RefSeqi XP_003983523.1. XM_003983474.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSFCAT00000004809 ; ENSFCAP00000004444 ; ENSFCAG00000004808 .
    GeneIDi 101098215.
    KEGGi fca:101098215.

    Organism-specific databases

    CTDi 7052.

    Phylogenomic databases

    GeneTreei ENSGT00740000115156.
    KOi K05625.
    OMAi ANGRDHH.
    OrthoDBi EOG7WT40M.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    3.90.260.10. 1 hit.
    InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
    IPR013783. Ig-like_fold.
    IPR014756. Ig_E-set.
    IPR002931. Transglutaminase-like.
    IPR008958. Transglutaminase_C.
    IPR013808. Transglutaminase_CS.
    IPR001102. Transglutaminase_N.
    [Graphical view ]
    PANTHERi PTHR11590. PTHR11590. 1 hit.
    Pfami PF00927. Transglut_C. 2 hits.
    PF01841. Transglut_core. 1 hit.
    PF00868. Transglut_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
    SMARTi SM00460. TGc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49309. SSF49309. 2 hits.
    SSF81296. SSF81296. 1 hit.
    PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AbyssinianImported.
    2. "Sequence assembly of the Felis catus genome version 6.2."
      Hillier L.W., Warren W., Obrien S., Wilson R.K.
      Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AbyssinianImported.
    3. Ensembl
      Submitted (MAR-2013) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: breed AbyssinianImported.

    Entry informationi

    Entry nameiM3W2W5_FELCA
    AccessioniPrimary (citable) accession number: M3W2W5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2013
    Last sequence update: May 1, 2013
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3