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M3W2W5

- M3W2W5_FELCA

UniProt

M3W2W5 - M3W2W5_FELCA

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Protein
Submitted name:

Uncharacterized protein

Gene

TGM2

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771UniRule annotation
Active sitei335 – 3351UniRule annotation
Active sitei358 – 3581UniRule annotation
Metal bindingi398 – 3981CalciumUniRule annotation
Metal bindingi400 – 4001CalciumUniRule annotation
Metal bindingi447 – 4471CalciumUniRule annotation
Metal bindingi452 – 4521CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. apoptotic cell clearance Source: Ensembl
  2. branching involved in salivary gland morphogenesis Source: Ensembl
  3. negative regulation of endoplasmic reticulum calcium ion concentration Source: Ensembl
  4. peptide cross-linking Source: InterPro
  5. positive regulation of cell adhesion Source: Ensembl
  6. positive regulation of mitochondrial calcium ion concentration Source: Ensembl
  7. salivary gland cavitation Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM2Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
ProteomesiUP000011712: Chromosome A3

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
InParanoidiM3W2W5.
KOiK05625.
OMAiANGRDHH.
OrthoDBiEOG7WT40M.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M3W2W5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEELVLERC DLELEANGRD HHTADLCREK LVVRRGQAFR LTLHFEGRNY
60 70 80 90 100
EASVDRLTFS VTTGPAPSEE AGTRARFPLS DAVEEGAWTA EVVGQQDSAL
110 120 130 140 150
SLQLSTPPNA PIGLYRLSLE ASTGYQGSSF VLGHFILLFN PWCPGDAVYL
160 170 180 190 200
DSDEERHEYI LTQHGFIYQG LATFIKNIPW NFGQFEDGIL DICLTLLDMN
210 220 230 240 250
PKFLRDAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGIS
260 270 280 290 300
PMFWIGSVDI LRRWKSSGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN
310 320 330 340 350
YNSAHDQNSN LLIEYFRNEF GEIQGDKSEM IWNFHCWVES WMSRPDLQPG
360 370 380 390 400
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD
410 420 430 440 450
VVDWIRQDDG SMHKSINHSL VVGLKISTKS VGRDERQDIT HTYKYPEGSP
460 470 480 490 500
EEREAFKRAN HLNKLTEKED TGMAMRIRVS QSMSMGSDFD VFAYITNNTS
510 520 530 540 550
EEHTCRLLLC ARTVSYNGIL GPECGTKDLL NLSLAPFSEK SIPLRILYEK
560 570 580 590 600
YCDCLTESNL IKVRGLLTEP AVNSYLLAER DIYLENPEIK IRILGEPKQK
610 620 630 640 650
RKLVAEVSLR NPLTTPLSDC IFTVEGAGLT EEQKVVEIPD PVEAGEDAKV
660 670 680
RVDLLPLHVG RHKLVVNFES DKLKAVKGFR NVIVGPA
Length:687
Mass (Da):77,162
Last modified:May 1, 2013 - v1
Checksum:i3E8AF10B929170CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AANG02187171 Genomic DNA. No translation available.
RefSeqiXP_003983523.1. XM_003983474.2.

Genome annotation databases

EnsembliENSFCAT00000004809; ENSFCAP00000004444; ENSFCAG00000004808.
GeneIDi101098215.
KEGGifca:101098215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AANG02187171 Genomic DNA. No translation available.
RefSeqi XP_003983523.1. XM_003983474.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSFCAT00000004809 ; ENSFCAP00000004444 ; ENSFCAG00000004808 .
GeneIDi 101098215.
KEGGi fca:101098215.

Organism-specific databases

CTDi 7052.

Phylogenomic databases

GeneTreei ENSGT00760000119108.
InParanoidi M3W2W5.
KOi K05625.
OMAi ANGRDHH.
OrthoDBi EOG7WT40M.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  2. "Sequence assembly of the Felis catus genome version 6.2."
    Hillier L.W., Warren W., Obrien S., Wilson R.K.
    Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  3. Ensembl
    Submitted (MAR-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: breed AbyssinianImported.

Entry informationi

Entry nameiM3W2W5_FELCA
AccessioniPrimary (citable) accession number: M3W2W5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: October 29, 2014
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3