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M3W2W5

- M3W2W5_FELCA

UniProt

M3W2W5 - M3W2W5_FELCA

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Protein
Submitted name: Uncharacterized protein
Gene
TGM2
Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 calcium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei277 – 2771 By similarityUniRule annotation
Active sitei335 – 3351 By similarityUniRule annotation
Active sitei358 – 3581 By similarityUniRule annotation
Metal bindingi398 – 3981Calcium By similarityUniRule annotation
Metal bindingi400 – 4001Calcium By similarityUniRule annotation
Metal bindingi447 – 4471Calcium By similarityUniRule annotation
Metal bindingi452 – 4521Calcium By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: Ensembl

GO - Biological processi

  1. apoptotic cell clearance Source: Ensembl
  2. branching involved in salivary gland morphogenesis Source: Ensembl
  3. peptide cross-linking Source: InterPro
  4. positive regulation of cell adhesion Source: Ensembl
  5. salivary gland cavitation Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TGM2Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
ProteomesiUP000011712: Chromosome A3

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00740000115156.
KOiK05625.
OMAiANGRDHH.
OrthoDBiEOG7WT40M.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

M3W2W5-1 [UniParc]FASTAAdd to Basket

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MAEELVLERC DLELEANGRD HHTADLCREK LVVRRGQAFR LTLHFEGRNY    50
EASVDRLTFS VTTGPAPSEE AGTRARFPLS DAVEEGAWTA EVVGQQDSAL 100
SLQLSTPPNA PIGLYRLSLE ASTGYQGSSF VLGHFILLFN PWCPGDAVYL 150
DSDEERHEYI LTQHGFIYQG LATFIKNIPW NFGQFEDGIL DICLTLLDMN 200
PKFLRDAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR WDNNYGDGIS 250
PMFWIGSVDI LRRWKSSGCQ RVKYGQCWVF AAVACTVLRC LGIPTRVVTN 300
YNSAHDQNSN LLIEYFRNEF GEIQGDKSEM IWNFHCWVES WMSRPDLQPG 350
YEGWQALDPT PQEKSEGTYC CGPVPVRAIK EGDLSTKYDA PFVFAEVNAD 400
VVDWIRQDDG SMHKSINHSL VVGLKISTKS VGRDERQDIT HTYKYPEGSP 450
EEREAFKRAN HLNKLTEKED TGMAMRIRVS QSMSMGSDFD VFAYITNNTS 500
EEHTCRLLLC ARTVSYNGIL GPECGTKDLL NLSLAPFSEK SIPLRILYEK 550
YCDCLTESNL IKVRGLLTEP AVNSYLLAER DIYLENPEIK IRILGEPKQK 600
RKLVAEVSLR NPLTTPLSDC IFTVEGAGLT EEQKVVEIPD PVEAGEDAKV 650
RVDLLPLHVG RHKLVVNFES DKLKAVKGFR NVIVGPA 687
Length:687
Mass (Da):77,162
Last modified:May 1, 2013 - v1
Checksum:i3E8AF10B929170CF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AANG02187171 Genomic DNA. No translation available.
RefSeqiXP_003983523.1. XM_003983474.2.

Genome annotation databases

EnsembliENSFCAT00000004809; ENSFCAP00000004444; ENSFCAG00000004808.
GeneIDi101098215.
KEGGifca:101098215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AANG02187171 Genomic DNA. No translation available.
RefSeqi XP_003983523.1. XM_003983474.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSFCAT00000004809 ; ENSFCAP00000004444 ; ENSFCAG00000004808 .
GeneIDi 101098215.
KEGGi fca:101098215.

Organism-specific databases

CTDi 7052.

Phylogenomic databases

GeneTreei ENSGT00740000115156.
KOi K05625.
OMAi ANGRDHH.
OrthoDBi EOG7WT40M.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProi IPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view ]
PANTHERi PTHR11590. PTHR11590. 1 hit.
Pfami PF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000459. TGM_EBP42. 1 hit.
SMARTi SM00460. TGc. 1 hit.
[Graphical view ]
SUPFAMi SSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEi PS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  2. "Sequence assembly of the Felis catus genome version 6.2."
    Hillier L.W., Warren W., Obrien S., Wilson R.K.
    Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AbyssinianImported.
  3. Ensembl
    Submitted (MAR-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: breed AbyssinianImported.

Entry informationi

Entry nameiM3W2W5_FELCA
AccessioniPrimary (citable) accession number: M3W2W5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: July 9, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi