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Protein

S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Gene

queA

Organism
Hydrogenobaculum sp. HO
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).UniRule annotationSAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.UniRule annotationSAAS annotation

Pathwayi: tRNA-queuosine biosynthesis

This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseImported, TransferaseUniRule annotationSAAS annotationImported
Biological processQueuosine biosynthesisUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciHSP547144:G1HFG-503-MONOMER
UniPathwayiUPA00392

Names & Taxonomyi

Protein namesi
Recommended name:
S-adenosylmethionine:tRNA ribosyltransferase-isomeraseUniRule annotationSAAS annotation (EC:2.4.99.17UniRule annotationSAAS annotation)
Alternative name(s):
Queuosine biosynthesis protein QueAUniRule annotation
Gene namesi
Name:queAUniRule annotation
ORF Names:HydHO_0495Imported
OrganismiHydrogenobaculum sp. HOImported
Taxonomic identifieri547144 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeHydrogenobaculum
Proteomesi
  • UP000011725 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the QueA family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK07568
OrthoDBiPOG091H00ZG

Family and domain databases

HAMAPiMF_00113 QueA, 1 hit
InterProiView protein in InterPro
IPR003699 QueA
IPR036100 QueA_sf
PANTHERiPTHR30307 PTHR30307, 1 hit
PfamiView protein in Pfam
PF02547 Queuosine_synth, 1 hit
SUPFAMiSSF111337 SSF111337, 1 hit
TIGRFAMsiTIGR00113 queA, 1 hit

Sequencei

Sequence statusi: Complete.

M1RCK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDISLFDYDL PEELIAKYPV NPRHSAKLMV LDRKSSNITH STFWHIDEFL
60 70 80 90 100
EEGDLLIFND TKVLPARLLG KKKGIENSNV EILLLRHLEN EKWEALVGGK
110 120 130 140 150
NIKPGLVIEI SDDFEAIIHS QIEKSKFLVL LKAKNQNQIE AINKYGKIPI
160 170 180 190 200
PPYLGRDEEP IDKEFYQTVF AKKEFSVAAP TASLHFSKEL LEKLKKKVNI
210 220 230 240 250
DFVTLHVSYG TFKPVTVQNI EEHKVDEEYI EVSESLIKNI KKTKEMGKRV
260 270 280 290 300
IAVGTTVTRA LETAIDKPYF GFTDLYIKPG FKFKVLDGLI TNFHLPKSSL
310 320 330 340
LILVSAFCNT KNLNGREFIL KAYKEAVKHK YRFYSYGDGM LIF
Length:343
Mass (Da):39,359
Last modified:May 1, 2013 - v1
Checksum:i476C3F8AA94734A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004347 Genomic DNA Translation: AGG14826.1
RefSeqiWP_015419115.1, NC_020411.1

Genome annotation databases

EnsemblBacteriaiAGG14826; AGG14826; HydHO_0495
KEGGihho:HydHO_0495
PATRICifig|547144.3.peg.502

Similar proteinsi

Entry informationi

Entry nameiM1RCK6_9AQUI
AccessioniPrimary (citable) accession number: M1RCK6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2013
Last sequence update: May 1, 2013
Last modified: May 23, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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